All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”
EN
ČeštinaEnglish

Filters

11 667 (0,091s) •

Project

Synthesis of compounds affecting mitochondrial enzymes as potential drugs for Alzheimer disease (LD14009)

and in vitro tested on University of St. Andrews. Furthermore, the molecular modellingThe main aim of the project is synthesis, in vitro evaluation, molecular modelling and structure-activity relationship determin...

CC - Organická chemie

  • 2014 - 2015
    • •
  • 1 364 tis. Kč
    • •
  • 1 364 tis. Kč
    • •
  • MŠMT
Project

Flavonoid derivatives as standards for in vitro colon models (LUC25026)

The aim of the project is to 1. Synthetize a library of commercially unavailable flavonoids 2. Prepare sulfated and glucuronidated metabolites of both flavonoids and their break-down products 3. Enzymatically produce depsides derived from the mos...

Biochemistry and molecular biology

  • 2025 - 2028
    • •
  • 7 860 tis. Kč
    • •
  • 7 860 tis. Kč
    • •
  • MŠMT
Project

In vitro 3-dimensional liver models to study cyanotoxin-induced chronic hepatotoxicity and liver diseases. (GA19-19143S)

of 3D liver in vitro models derived from normal or transformed liver stem will iimprove in vitro liver models for chronic hepatotoxicity assessment and will provide in the liver tissue and thus allow more reliable...

Public and environmental health

  • 2019 - 2023
    • •
  • 5 800 tis. Kč
    • •
  • 5 722 tis. Kč
    • •
  • GA ČR
Project

Selection of potential probiotic Lactobacillus strains for allergy-prevention What can we learn from in vitro studies? (7AMB15AT025)

strains in vitro (Austria); 2. To identify the molecular mechanisms required for induction of cytokines in vitro (Austria and Czech Republic); and 3. To investigate the correlationbetween the in vitro immune profiles of 2 ...

EC - Imunologie

  • 2015 - 2016
    • •
  • 122 tis. Kč
    • •
  • 122 tis. Kč
    • •
  • MŠMT
Project

Microenvironment of malignant melanoma as a factor of tumor aggressiveness (GA16-05534S)

in an in vitro model and in vivo in a porcine model....

EA - Morfologické obory a cytologie

  • 2016 - 2018
    • •
  • 9 848 tis. Kč
    • •
  • 8 801 tis. Kč
    • •
  • GA ČR
Project

Physiologically based prediction of pharmacokinetics prior to in vivo studies Focus on hepatic and renal drug elimination (1P05OC061)

possibilities of combined usage of in vitro methods and computational models in silico for prediction of pharmacokinetics in vivo...

FR - Farmakologie a lékárnická chemie

  • 2005 - 2008
    • •
  • 2 526 tis. Kč
    • •
  • 2 526 tis. Kč
    • •
  • MŠMT
Project

Adhesive properities of probiotics to the intestinal epithelium (LD14070)

MTX co-cultures. 2. To evaluate the adhesive properties in vitro. The newly validated in vitro model will be used to test the adhesive properties of rifampicinThe aim of the project is: 1. To validate the in vitro...

GM - Potravinářství

  • 2014 - 2015
    • •
  • 895 tis. Kč
    • •
  • 895 tis. Kč
    • •
  • MŠMT
Project

A new generation of in vitro intestinal barrier models for evaluating the effects of drugs and food ingredients (LUC25122)

CA23110 – International networking on in vitro colon models simulating gut microbiota be summarized as follows: - Creation of an advanced model of the physiological intestinal - Preparation of a pathological model...

Biochemistry and molecular biology

  • 2025 - 2028
    • •
  • 4 996 tis. Kč
    • •
  • 4 996 tis. Kč
    • •
  • MŠMT
Project

Phytoremediation modelling - "in vitro" biodegradations of chlorinated phenols and related compounds (OC 837.30)

The phytoremediation method can be recently considered as the very important in the environmental decontamination processes. The project solves biotransformations of exogenous substrates by enzymic systems of higher plants in model "in v...

CC - Organická chemie

  • 1999 - 2003
    • •
  • 4 894 tis. Kč
    • •
  • 2 165 tis. Kč
    • •
  • MŠMT
Project

Critical assessment of some current natural products with potential therapeutic applications in liver injuries in vivo and in vitro evaluation (NR9379)

. - The application of several different experimental animal models (in vivo) and cellular models (in vitro) will be adopted to study the liver injury produced by different insults whether chemical, immunological or surgica...

FR - Farmakologie a lékárnická chemie

  • 2007 - 2009
    • •
  • 2 843 tis. Kč
    • •
  • 2 787 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 11 667