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9 (0,091s) •

Project

The Role of Skp1-Cullin1-F-box Complex in Protein Ubiquitination and Degradation during Bovine Preimplantation Development (GP13-24730P)

of two basic subtypes of ubiquitin-ligases; SCF (Skp1-Cul1-Fbox) complex; during preimplantation development. The SCF-complex role during degradation of maternal proteins of SCF-complex will be identified. The gained resul...

EB - Genetika a molekulární biologie

  • 2013 - 2018
    • •
  • 2 709 tis. Kč
    • •
  • 2 709 tis. Kč
    • •
  • GA ČR
Project

The role of SCF-FBXO28 ubiquitin ligase in cancer progression (GA18-27408S)

will focus on E3 ubiquitin ligase SCF-FBXO28. Recently, we identified proteins ARHGEF6/7 we will describe signaling pathways regulating SCF-FBXO28-dependent......

Cell biology

  • 2018 - 2022
    • •
  • 8 559 tis. Kč
    • •
  • 7 833 tis. Kč
    • •
  • GA ČR
Project

Advanced single crystalline film scintillators based on the complex oxide compounds energy transfer engineering for performance optimization (GF24-14580L)

The aim is to develop efficient single crystalline film (SCF) scintillators based on the Ce, Tb and Eu doped multicomponent (Lu,Gd,Tb)3Al5O12 garnets, (Lu,Gd resolution. The unique approach is to compare SCF with the single crystal ...

Condensed matter physics (including formerly solid state physics, supercond.)

  • 2024 - 2026
    • •
  • 5 281 tis. Kč
    • •
  • 5 148 tis. Kč
    • •
  • GA ČR
Project

Red blood cells in cyprinid fish (GA16-21024S)

) and stem cell factor (SCF, or Kit ligand, Kitl). We have chosen zebrafish (Danio rerio...

EB - Genetika a molekulární biologie

  • 2016 - 2020
    • •
  • 6 972 tis. Kč
    • •
  • 5 991 tis. Kč
    • •
  • GA ČR
Project

Development of SUBCHANFLOW (SCF) model for Sub-Channel Thermohydraulic Analysis of the reactor core and its validation by the code to code method. (TK01010170)

The aim is to develop a computational model for the sub-channel thermohydraulic analysis of the VVER 1000 reactor (type JE Temelín) including its validation by comparison with the results of simulation of normal operation, abnormal operation and sele...

Nuclear related engineering; (nuclear physics to be 1.3);

  • 2018 - 2020
    • •
  • 8 121 tis. Kč
    • •
  • 4 626 tis. Kč
    • •
  • TA ČR
Project

Multidisciplinary study of aqueous solutions of branched polyelectrolytes (GA203/07/0659)

In this project, we propose a complex study of solutions of branched polyelectrolytes (both quenched and annealed) in aqueous media by a combination of computer simulations (molecular and Langevin dynamics, Monte Carlo, mean-field SCF) and e...

CD - Makromolekulární chemie

  • 2007 - 2009
    • •
  • 3 061 tis. Kč
    • •
  • 3 061 tis. Kč
    • •
  • GA ČR
Project

Molecular Dynamics Simulations of Annealed Polyelectrolytes (KJB401110701)

The aim of the project is to study weak polyelectrolytes (PEs) using molecular dynamics (MD) simulations. Weak PEs have peculiar properties and many applications in industry and technology. They are an essential part of biological systems, since most...

CD - Makromolekulární chemie

  • 2007 - 2009
    • •
  • 998 tis. Kč
    • •
  • 998 tis. Kč
    • •
  • AV ČR
Project

Conformational behavior and (co)self-assembly of new double-hydrophilic and amphiphilic block polyelectrolytes. Thermodynamic and kinetic aspects. (GAP106/12/0143)

data will be interpreted with help of computer simulations (MC, MD and SCF...

CD - Makromolekulární chemie

  • 2012 - 2016
    • •
  • 12 762 tis. Kč
    • •
  • 12 762 tis. Kč
    • •
  • GA ČR
Project

Role of RECQ5 DNA helicase in maintenance of genomic stability (GA204/09/0565)

the biological function of the interaction between RECQ5 and SKP1, scaffold component of SCF...

EB - Genetika a molekulární biologie

  • 2009 - 2013
    • •
  • 8 570 tis. Kč
    • •
  • 8 570 tis. Kč
    • •
  • GA ČR
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