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767 (0,07s) •

Project

Mechanism of action of polymeric drugs and their intracellular distribution (GP305/04/P004)

At present, the polymeric conjugates based on poly N-(2-hydroxypropyl. Conjugation of doxorubicin with a polymeric carrier and optionally targeted with targeting different forms of polymeric conjugates...

EC - Imunologie

  • 2004 - 2006
    • •
  • 851 tis. Kč
    • •
  • 851 tis. Kč
    • •
  • GA ČR
Project

THE EFFECT OF HPMA DRUG BASED THERAPY ON THE LOCAL TUMOR MICROENVIRONMENT (IAA400200702)

Polymeric conjugates based on N-(2-hydroxypropyl)methacrylamide bearing is to characterize the behavior of polymeric conjugates inside the tumor and different effects of tumor microenvironment could help us to desi...

CD - Makromolekulární chemie

  • 2007 - 2011
    • •
  • 5 878 tis. Kč
    • •
  • 5 878 tis. Kč
    • •
  • AV ČR
Project

Conjugated polymers based materials as luminescence chemosensors (GA17-05318S)

New conjugated polymer based chemosensors with tailored architecture of the proposed conjugated polymers in combination with modification of the properties of 1,8-naphthalimide fluorophore connected to the conjugated polyme...

CD - Makromolekulární chemie

  • 2017 - 2019
    • •
  • 6 274 tis. Kč
    • •
  • 6 204 tis. Kč
    • •
  • GA ČR
Project

Development of catalytic processes for preparation of heteroatoms-containing conjugated polymers and their functional nanocomposites (GA104/06/1087)

in the development of catalytic processes for oxidative polymerization of monomers such as anilines, thiophenes and pyrroles to high-purity conjugated polymers and application appropriate ligands to optimize the catalytic system fo...

JI - Kompositní materiály

  • 2006 - 2008
    • •
  • 2 873 tis. Kč
    • •
  • 2 873 tis. Kč
    • •
  • GA ČR
Project

Interpenetrating polyacetylene based polymeric networks prepared by "click" chemistry (GA203/09/0803)

Highly conjugated pyridine-derived groups containing polyacetylene copolymers will be prepared by (i) polymerization via quarternization, (ii) catalytic coordination polymerization and (iii) polycyclotrimerization of monoet...

CD - Makromolekulární chemie

  • 2009 - 2011
    • •
  • 2 026 tis. Kč
    • •
  • 2 026 tis. Kč
    • •
  • GA ČR
Project

Targeting cancer chemoresistance by polymeric conjugates for selective delivery of cytostatic drug and inhibitors of Pg-p and STAT3 into solid tumors (GA19-05649S)

for insensitivity to these drugs. Moreover, high-molecular-weight polymeric conjugates possess suggest to employ drug delivery system based on HPMA copolymer conjugates bearing. Such conjugates should be capable t...

Oncology

  • 2019 - 2022
    • •
  • 9 685 tis. Kč
    • •
  • 9 613 tis. Kč
    • •
  • GA ČR
Project

Targeted inhibition of the metastatic process by biodegradable polymeric conjugates with MMP inhibitors and cytostatic drugs (GA17-13283S)

of novel polymeric therapeutics based on high-molecular-weight (HMW) HPMA copolymer of the conjugate will be actively targeted to cells involved in angiogenesis by ATR1-binding......

FD - Onkologie a hematologie

  • 2017 - 2020
    • •
  • 9 097 tis. Kč
    • •
  • 8 490 tis. Kč
    • •
  • GA ČR
Project

Polymeric materials for photoelectrically active detectors. (IAA4050603)

The aim of this project is to develop new photoelectrically sensitive polymers with delta- and pí- conjugated main chain and pí- conjugated functional side groups. Polymer composites will be prepared using polymers with saturated ma...

CC - Organická chemie

  • 1996 - 1998
    • •
  • 3 230 tis. Kč
    • •
  • 1 460 tis. Kč
    • •
  • AV ČR
Project

Formation of a polymer layer from monomers adsorbed at a liquid/liquid interface (ME 510)

Formation of self-assembled adsorbed layers at the interface between two immiscible electrolyte solutions and their subsequent polymerization will be studied-pyrrole nucleus and conjugated chemical multibonds, to enhance the stabili...

CG - Elektrochemie

  • 2002 - 2004
    • •
  • 2 545 tis. Kč
    • •
  • 912 tis. Kč
    • •
  • MŠMT
Project

The Study of Molecular Structure and Reactions on Highly Oriented Polymeric Films Using Scanning Probe Microscopy. (IAA4040605)

Scanning probe microscopy as a high resolution technique will be used for the study and characterization of polymeric films. Atomically flat surfaces of polymeric in the polymeric matrix. The deposition of oriented films on...

CF - Fyzikální chemie a teoretická chemie

  • 1996 - 1998
    • •
  • 2 128 tis. Kč
    • •
  • 1 128 tis. Kč
    • •
  • AV ČR
  • 1 - 10 out of 767