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12 (0,127s) •

Project

The smoking cessation and hormonal homeostasis oriented to neuroactive steroids (NS10215)

The influence of smoking on the biosynthesis of steroids is still not fully described. We will run the metabolic analysis covering almost all known metabolic steps of the steroidogenesis. Nicotine metabolites inhibit the 3alpha-hydroxysteroi...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2009 - 2011
    • •
  • 4 441 tis. Kč
    • •
  • 4 441 tis. Kč
    • •
  • MZ
Project

Locally active enzymes of steroidogenesis and their influencing by selected endogenous and exogenous factors. (IZ4289)

The stufy of influence of selected enzymes of steroid metabolism, namely: 11beta-hydroxysteroid dehydrogenase, extrahepatal 5alfa-reductase, aromatase and 7alfa-hydroxylase. The study will be performed by some endogenous and exogenous factors.......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1997 - 1999
    • •
  • 1 840 tis. Kč
    • •
  • 1 315 tis. Kč
    • •
  • MZ
Project

In vitro models for study of endocrine disruption - effects of traditional and new types of persistent organic pollutants (GP525/05/P160)

, retinoid) and steroidogenesis. The methods can be used to study important pollutants...

DN - Vliv životního prostředí na zdraví

  • 2005 - 2007
    • •
  • 702 tis. Kč
    • •
  • 702 tis. Kč
    • •
  • GA ČR
Project

Cellular and molecular methods for assessment of endocrine disruption (1K04006)

The project supports the stay of Czech scientist in the USA with the aims to obtain new experiences with molecular biological techniques in ecotoxicology, to study endocrine disruption mechanisms, to bring the knowledge and support research in CR......

DN - Vliv životního prostředí na zdraví

  • 2004 - 2004
    • •
  • 765 tis. Kč
    • •
  • 452 tis. Kč
    • •
  • MŠMT
Project

The role of microbiota in the regulation of extra-adrenal steroidogenesis and local metabolism of glucococorticoids during stress (GA18-02993S)

revealed that additional organs express enzymes of steroidogenesis of GCs and enzymes...

Physiology (including cytology)

  • 2018 - 2020
    • •
  • 10 028 tis. Kč
    • •
  • 9 602 tis. Kč
    • •
  • GA ČR
Project

Effect of Hemodialysis and Renal Transplantation on Reproduction Function in Men with Chronic Renal Insufficiency (NS10431)

The male infertility factor accounts for about the 20% to 50% share in overall infertility in couples. In men with chronic renal insufficiency, affection of gonadal functions occurs ? both spermiogenesis and steroidogenesis, as well as of se...

FJ - Chirurgie včetně transplantologie

  • 2009 - 2011
    • •
  • 2 517 tis. Kč
    • •
  • 2 507 tis. Kč
    • •
  • MZ
Project

Function of the nuclear receptor NHR-25/FTZ-F1 in Caenorhabditis elegans development (KJB5022303)

and steroidogenesis in mouse. We have shown the requrement of NHR-25 for C. elegans embryogenesis, in steroidogenesis. Defining the mode of NHR-25 action addresses some fundamental problems......

EB - Genetika a molekulární biologie

  • 2003 - 2005
    • •
  • 1 167 tis. Kč
    • •
  • 1 043 tis. Kč
    • •
  • AV ČR
Project

Prediction of termination of pregnancy in women with serious hepatopathies (NT12211)

components of steroidogenesis and synthesis of bile acids in pregnancy using...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2011 - 2015
    • •
  • 7 549 tis. Kč
    • •
  • 7 549 tis. Kč
    • •
  • MZ
Project

Neuroendocrine regulation of ovulation and spermiation in Cypriniformes (GP13-39438P)

The proposed project is focused on hypothalamic regulation of reproduction in Cypriniformes. Research interest will be devoted to elucidation of GnRH and Dopamine induced release of FSH and LH during reproduction period in Cypriniformes. Special atte...

GL - Rybářství

  • 2013 - 2017
    • •
  • 2 850 tis. Kč
    • •
  • 2 850 tis. Kč
    • •
  • GA ČR
Project

Study of the genetic background of the polycystic ovary syndrome (GA301/04/1085)

The polycystic ovary syndrome (PCOS) is the most common endocrinopathy of the women of reproductive age and is major cause of anovulatory infertility and hirsutism. The genetic background of disturbances in steroidogenesis and insulin resist...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2004 - 2006
    • •
  • 4 460 tis. Kč
    • •
  • 4 454 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 12