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14 (0,152s) •

Project

NMR study of interaction of cisplatined G/T mismatched DNA substrate with protein MutS (GP202/08/P416)

The DNA mismatch repair (MMR) system corrects mispaired or unpaired bases as well as other DNA lesions, thus  plays a critical role in sensitizing both prokaryotic and eukaryotic cells to the clinically potent anticancer drug cisplatin by

BO - Biofyzika

  • 2008 - 2010
    • •
  • 750 tis. Kč
    • •
  • 750 tis. Kč
    • •
  • GA ČR
Project

Telomere homeostasis as potential biomarker of risk, prognosis and progression in gynaecologic tumours. (NU21-03-00145)

(MMR) emerges as an important player in telomere homeostasis and genomic stability. Since OvC has also MMR deficiency in its etiology, addressing telomere homeostasis......

Oncology

  • 2021 - 2024
    • •
  • 10 438 tis. Kč
    • •
  • 10 438 tis. Kč
    • •
  • MZ
Project

Ensuring of Preparation for the next period 2014+ (ED5.1.00/05.0333)

of OP 2014 +, both by MMR - NOK, and the European Commission....

AE - Řízení, správa a administrativa

  • 2013 - 2014
    • •
  • 76 000 tis. Kč
    • •
  • 11 400 tis. Kč
    • •
  • MŠMT
Project

Epigenetic gene silencing in colorectal cancer- a potential biomarker for early diagnosis and efficacy of chemotherapy (GPP304/11/P715)

). As a significant proportion of CRCs develop through DNA mismatch repair (MMR) deficiency, we aim to explore whether epigenetic alterations in MMR genes could be present......

EB - Genetika a molekulární biologie

  • 2011 - 2013
    • •
  • 3 012 tis. Kč
    • •
  • 3 012 tis. Kč
    • •
  • GA ČR
Project

Advanced car make and model recognition (FW01010336)

The aim of the project is research and development of algorithms for the new generation of the vehicle Make and Model Recognition (MMR) system. In particular, the new system will be independent of car license plate detection, recognition wil...

Automation and control systems

  • 2020 - 2021
    • •
  • 7 500 tis. Kč
    • •
  • 4 118 tis. Kč
    • •
  • TA ČR
Project

RESEARCH CENTER FOR A RESILIENT, SMART, INNOVATIVE AND SUSTAINABLE SOCIETY (TQ12000017)

(MMR, 2021) and further support the creation and implementation of cohesion policy...

Public administration

  • 2024 - 2029
    • •
  • 154 783 tis. Kč
    • •
  • 123 811 tis. Kč
    • •
  • TA ČR
Project

WIM LATIN AMERICA (EG20_321/0025242)

The project is focused on innovation and gaining experience with the design and operation of a WIM system for export while exporting, focusing mainly on the Latin American environment and the development of SW modules. The aim is to innovate the syst...

Electrical and electronic engineering

  • 2021 - 2023
    • •
  • 7 321 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MPO
Project

Behavioral approaches to evidence-based decision-making in the Smart Cities Concept (TQ01000548)

pieces of information and facts” (MMR, 2021). The project aims to use mixed methods...

Public administration

  • 2023 - 2026
    • •
  • 6 736 tis. Kč
    • •
  • 5 389 tis. Kč
    • •
  • TA ČR
Project

Molecular and genetic biomarkers of ovarian cancer pathogenesis and resistance (NT14056)

and multifactorial regulation of gene expression will be performed. A role of MMR genes...

EB - Genetika a molekulární biologie

  • 2013 - 2015
    • •
  • 6 853 tis. Kč
    • •
  • 6 853 tis. Kč
    • •
  • MZ
Project

Clinically manifest mumps in the vaccinated population – genotyping of the causative virus and patient’s serological profile. (NT14059)

Although mumps vaccine is part of the routine childhood immunization schedule, mumps cases or outbreaks have been reported repeatedly. The reasons behind the re-emergence of the disease are not clear. One of the factors may be MMR vaccine fa...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2013 - 2015
    • •
  • 4 780 tis. Kč
    • •
  • 4 780 tis. Kč
    • •
  • MZ
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