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258 (0,102s) •

Project

Morphological and functional analysis of pituitary adenomas structure prediction and postoperative changes in nasal airflow and olfactory function (NW24-08-00324)

to enlighten postoperative anatomical changes of the nasal cavity and changes of the air circulation in the nasal cavity. Detailed knowledge of these changes can improve surgical......

Neurosciences (including psychophysiology)

  • 2024 - 2027
    • •
  • 11 705 tis. Kč
    • •
  • 11 705 tis. Kč
    • •
  • MZ
Project

Molecular and cellular mechanisms in ethiopathogenesis of nasal polyposis (NS10054)

molecules in nasal polyps. Expression of Toll-like receptors as potential markers for identifying etiological environmental factors in nasal polyps. Changes in expression of chemokine and cytokine receptors in nasal polyps...

FF - ORL, oftalmologie, stomatologie

  • 2008 - 2011
    • •
  • 2 140 tis. Kč
    • •
  • 2 140 tis. Kč
    • •
  • MZ
Project

IMMUNO - INFLAMMATORY MECHANISMS IN PATHOGENESIS OF NASAL POLYPOSIS (NR8517)

Activated mucosal immune cells in nasal polyps. Role of growth factors, cytokines and chemokines in NP. Innate immune mechanisms in pathogensis of nasal polyposis. Role of non-endothelial expression of ICAMs in nasal polypo...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2005 - 2007
    • •
  • 2 279 tis. Kč
    • •
  • 2 279 tis. Kč
    • •
  • MZ
Project

Nasal microbiome and molecular immune mechanisms in the prevention and pathogenesis of nasal polyps and chronic rhinitis; relation to olfactory disorders and allergies (NU22-09-00493)

Chronic rhinosinusitis (CRS) and CRS with nasal polyps (CRSwNP) represent a frequent and recurrent chronic inflammatory affection in the ENT practice possibly linked to their pathogenesis: nasal microbiome, olfactory dysfunctions, <...

Otorhinolaryngology

  • 2022 - 2025
    • •
  • 9 234 tis. Kč
    • •
  • 9 234 tis. Kč
    • •
  • MZ
Project

The study of the syndrome of aspirin intorelance as a risk factor in patients with nasal polyps. (IZ4051)

The goal of the study is to identify by challenge test among the patients with nasal polyposis the ones with incomplete syndrome of aspirin intolerance. These patients are likely to be threatened with bronchial asthma.They will be examined b...

FF - ORL, oftalmologie, stomatologie

  • 1997 - 1999
    • •
  • 1 124 tis. Kč
    • •
  • 867 tis. Kč
    • •
  • MZ
Project

Optimization of cystic fibrosis patient-derived cellular models to asses restoration of CFTR function in patients with cystic fibrosis (NU23-07-00079)

emerged in recent years, namely human nasal epithelial cells cultures differentiated in air-liquid interface (ALI) and nasal organoids. The proposed project aims to set nasal epithelial cells monolayers, nasal and...

Paediatrics

  • 2023 - 2026
    • •
  • 15 195 tis. Kč
    • •
  • 15 195 tis. Kč
    • •
  • MZ
Project

The Diagnostics of Extraesophageal Reflux with the Restech System in Patients with Chronic Rhinosinusitis (NT13500)

different patient groups (1. CHR without nasal polyposis, without asthma bronchiale or ASA syndrome, 2. CHR with nasal polyposis, without asthma bronchiale or ASA syndrome, 3. CHR with nasal polyposis and asthma bronchiale...

FF - ORL, oftalmologie, stomatologie

  • 2012 - 2015
    • •
  • 2 626 tis. Kč
    • •
  • 2 469 tis. Kč
    • •
  • MZ
Project

Intranasal vaccination in prevention of autoimmune diseases (NS10340)

Mechanisms of induction of mucosal protective immunity by intranasal administration of autoantigens using bioptic material of human nasal mucosa and mouse models of type 1. diabetes and ulcerative colitis. Role of NALT (Nasal associ...

EC - Imunologie

  • 2009 - 2011
    • •
  • 2 561 tis. Kč
    • •
  • 2 561 tis. Kč
    • •
  • MZ
Project

Development of various formulations containing bacteriophages associated with the production of nasal spray used in the prevention of MRSA. (EG21_374/0027103)

-nasal spray used to prevent infections caused by MRSA. At the same time...

Pharmacology and pharmacy

  • 2021 - 2024
    • •
  • 9 047 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MPO
Project

Interaction of the pertussis agent with ciliated epithelia of nasal mucosa (GX25-18104X)

infection in immunodeficient MyD88 KO mice, in which B. pertussis proliferates on nasal experiments on mice and primary human nasal ciliated epithelial cells to identify bacterial virulence factors that suppress innate defense mech...

Microbiology

  • 2025 - 2029
    • •
  • 50 000 tis. Kč
    • •
  • 50 000 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 258