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99 (0,281s)

Project

Plasticity of prostate cancer cells and chemotherapy resistance (7AMB16AT022)

1. Correlation of EMT fingerprint with chemotherapy resistance in prostate cancer 2. Analysis of novel molecular factors involved in EMT and chemotherapy resistance 3. Analysis of the role of miR-34a in EMT and chemotherapy resistance in

FD - Onkologie a hematologie

  • 2016 - 2017
  • 68 tis. Kč
  • 68 tis. Kč
  • MŠMT
Project

Use of MRI with transrectal ultrasonography fusion for detecting prostate cancer (NV15-27047A)

Prostate cancer is the most common malignancy in males in the Czech Republic. It can only be diagnosed by prostate biopsy; up to 30% of tumours, however, may imaging (mpMRI) has been used to improve prostate biopsy detectio...

FP - Ostatní lékařské obory

  • 2015 - 2019
  • 9 654 tis. Kč
  • 9 654 tis. Kč
  • MZ
Project

The study of sarcosine metabolism and its participation in prostate cancer development (GA16-18917S)

growth and aggressiveness of prostate cancer cells. Another aim is to identify a role of these enzymes and levels of sarcosine in prostate cancer cells under conditions analogous to treatment of prostate cancer patients. T...

CE - Biochemie

  • 2016 - 2018
  • 10 952 tis. Kč
  • 10 505 tis. Kč
  • GA ČR
Project

Laboratory and clinical testing of candidate markers for prostate cancer using samples from a complex cryobank of patients with long-term follow-up. (NV15-33910A)

Prostatic specific antigen (PSA) is not entirely reliable indicator of prostate with prostate cancer. By testing of stored samples we may find relatively quickly whether markers correlate with the presence or even with the ...

FD - Onkologie a hematologie

  • 2015 - 2018
  • 5 077 tis. Kč
  • 5 077 tis. Kč
  • MZ
Project

DD3, a New Tumor Marker For Gene Early Diagnostic Of Prostate Cancer (NR8918)

The aim of the study is to evaluate the meaning of the DD3 gene detection by means of RT PCR methodics for a timely diagnostics of prostate carcinoma in comparison with standardly used PSA determination. Data will be presented at our as well...

FD - Onkologie a hematologie

  • 2006 - 2008
  • 1 725 tis. Kč
  • 1 725 tis. Kč
  • MZ
Project

The Estrogen Stress Response in the Elderly Man and Its Possible Influence on the Development of the Benign Prostate Hyperplasia (BPH) and on the Prostate Cancer (CaP). (NB7613)

incidenceof their prostate disease involvement, as compared with the patients with lower therapy with estorgens in the elderly men have a prostate-protective implications......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2003 - 2005
  • 751 tis. Kč
  • 680 tis. Kč
  • MZ
Project

TRH-like peptides and the local prostatic hormonal network (NB6712)

The research of prostatic local autocrine/paracrine network formed by extrahypothalamic thyroliberine (TRH) immunoreactivity corresponded to TRH-like peptides and extrapituitary thyrotropin (TSH) immunoreactivity. The research of the relatio...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2001 - 2003
  • 4 178 tis. Kč
  • 3 778 tis. Kč
  • MZ
Project

Tumor markers, their determination and correlation with prostate carcinoma (NS10200)

Detailed analysis focused on individual tumour markers in correlation with prostate carcinoma in combination with new physiochemical methodology that accelerate and increase the sensitivity of their determination will performed.......

FD - Onkologie a hematologie

  • 2009 - 2011
  • 4 994 tis. Kč
  • 4 994 tis. Kč
  • MZ
Project

Role of S-phase kinase-associated protein 2 in biology of prostate cancer stem cells and tumor progression (NT13573)

1. Expression of Skp2 will be analyzed in various subpopulations of prostate pathways. 2. Importance of Skp2 in biology of cancer stem cells and prostate cancer in archive specimens of prostate cancer. 4. The obtained data ...

FD - Onkologie a hematologie

  • 2012 - 2015
  • 8 938 tis. Kč
  • 8 938 tis. Kč
  • MZ
Project

Tissue concentration of calcitonin in prostate as a marker of locally confined or disseminated prostatic cancer (IZ4058)

Prostatic tissue taken away by the radical prostatectomy should by homogenised and the level of calcitonin /ng/g/ and ploidity would be determined. Preoperativelly and in 6 month terms PSA, calcitonin, scintigraphy of bones should be perform...

FJ - Chirurgie včetně transplantologie

  • 1997 - 1999
  • 2 147 tis. Kč
  • 1 971 tis. Kč
  • MZ
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