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76 (0,211s)

Project

Structure and dynamics of 45S rDNA loci in Arabidopsis thaliana (LH15189)

The project aims: i) to describe the structure of both 45S rDNA chromosome loci, including the arrangement of active and inactive 45S rDNA variants, and to analyze proximal and distal borders of the 45S rDNA loci; ii) to fi...

EB - Genetika a molekulární biologie

  • 2015 - 2017
  • 1 972 tis. Kč
  • 1 972 tis. Kč
  • MŠMT
Project

Ribosomal stress, ribosomal DNA stability and cellular senescence role of PML (GA19-21325S)

ribosomopathies and cancer. rDNA repeats represent a most unstable component of eukaryotic genome. Mechanisms controlling the stability of rDNA regions in mammals cells are not understood. There is emerging evidence that rDNA

Human genetics

  • 2019 - 2023
  • 10 468 tis. Kč
  • 9 864 tis. Kč
  • GA ČR
Project

Dynamics and evolution of multigene ribosomal RNA loci in Triticeae (GA17-17564S)

Ribosomal RNA gene loci (rDNA) have been among extensively studied components the biological importance, detailed information on molecular organization of rDNA regions is missing, especially in plants. This is mainly due to structur...

EB - Genetika a molekulární biologie

  • 2017 - 2020
  • 5 128 tis. Kč
  • 4 489 tis. Kč
  • GA ČR
Project

The structure and the expression of ribosomal RNA genes in allotetraploid and their parental plant genomes (GP204/03/P104)

and positions of nucleosomes on tandemly repeated 5S rDNA sequences of Nicotiana sylvestris of 5S rDNA tandem units in N. tomentosiformis will be mapped. The sequence ontranscription of 5S rDNA genes will be verified by "n...

EB - Genetika a molekulární biologie

  • 2003 - 2005
  • 750 tis. Kč
  • 750 tis. Kč
  • GA ČR
Project

Molecular organization and evolution of the 45S rDNA locus in banana (Musa spp.) (IAA600380703)

We propose to analyze molecular organization of the 45S rDNA (ribosomal DNA of the 45S rDNA cluster in banana will be obtained and used to analyze insertion of repetitive DNA sequences within the rDNA array. rDNA l...

EF - Botanika

  • 2007 - 2010
  • 3 519 tis. Kč
  • 3 519 tis. Kč
  • AV ČR
Project

The influence of allopolyploidy on the evolution and expression of rDNA loci in plants (GA22-16826S)

). The ribosomal RNA genes (rDNA) are essential components of every cell playing the pivotal conservation rDNA exhibits striking diversity in position on chromosomes and locus numbers is preceded by interspecies hybridization) on

Plant sciences, botany

  • 2022 - 2024
  • 11 834 tis. Kč
  • 11 652 tis. Kč
  • GA ČR
Project

The impact of genomic shock associated with interspecific hybridization and polyploidization on evolution of rDNA loci in young invasive weeds. (GA206/09/1751)

Both genetic and epigenetic alterations in parental rDNA accompanying will be studied to answer following questions: (i) Are alterations in parental rDNA similar modification and chromatin packaging different in dominant and silent ...

EB - Genetika a molekulární biologie

  • 2009 - 2013
  • 3 819 tis. Kč
  • 3 819 tis. Kč
  • GA ČR
Project

Building Barbara McClintock’s legacy Evolution of ribosomal DNA in chromosomal context (GA25-16796S)

Ribosomal RNA genes (rDNAs) have long fascinated researchers, representing, rDNAs wield disproportionate influence, orchestrating crucial cellular processes with rDNAs dynamism in chromosomes has motivated us to re-open old...

Genetics and heredity (medical genetics to be 3)

  • 2025 - 2027
  • 15 123 tis. Kč
  • 14 802 tis. Kč
  • GA ČR
Project

Exploring the role of PML nucleolar compartment in rDNA maintenance in normal and cancer cells (GA23-07273S)

and alternative lengthening of telomeres. Genes coding human rDNA are placed on five evidence that rDNA instability is related to the development of aging disorders, including cancer progression. The project's primary goal is to cl...

Cell biology

  • 2023 - 2025
  • 6 870 tis. Kč
  • 6 870 tis. Kč
  • GA ČR
Project

Genetic and epigenetic features of rDNA intergenic spacers and their potential regulatory functions in the establishment of nucleolar dominance (GA17-11642S)

Though the epigenetic mechanisms of rDNA silencing are well known, it remains unclear how only one rDNA homeolog is chosen for inactivation in genetic hybrids to analyse rDNA intergenic spacer (IGS) variants with extraordin...

EB - Genetika a molekulární biologie

  • 2017 - 2019
  • 6 483 tis. Kč
  • 6 105 tis. Kč
  • GA ČR
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