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2 028 (0,117s)

Project

"Tailoring" therapy of chronic viral hepatitis B and C interferonem alfa (IZ4234)

Optimalization of interferon alpha therapy ("tailoring"therapy) in patients with chronic hepatitis B and C using monitoring viremia and detection of hepatitis C virus serotype.......

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1997 - 1999
  • 1 981 tis. Kč
  • 1 378 tis. Kč
  • MZ
Project

The hepatitis C transmission in kidney transplants. (IZ3646)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1996 - 1998
  • 811 tis. Kč
  • 811 tis. Kč
  • MZ
Project

Comparison of efficacy of combination and induction treatment of chronic viral hepatitis C controlled multicentre randomised study (NI6015)

The author submits a controlled randomised study. Its objective is to verify the effectiveness of 2 new therapeutic schedules in the treatment of chronic viral hepatitis C. The study is supported by the Committee of the Czech Hepato...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2000 - 2002
  • 2 717 tis. Kč
  • 2 716 tis. Kč
  • MZ
Project

Noninvasive hepatitis C virus detection in liver and brain by 31 MR spectroscopy (NR7853)

The project objective is the correlation between clinical and MR data of the liver and brain in patients with hepatitis C and thus make a contribution to clinical evaluation of those patients and to an appropriate treatment plan pro...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2004 - 2006
  • 2 386 tis. Kč
  • 2 221 tis. Kč
  • MZ
Project

Role of the host-dependent factors in prediction of antiviral treatment response in chronic hepatitis C (NT11235)

We shall validate the significance of the polymorphism -764G/C in the interferon gamma gene promoter and polymorphisms in IL28B gene in prediction of treatment response in chronic hepatitis C with peginterferon alpha and ri...

FE - Ostatní obory vnitřního lékařství

  • 2010 - 2015
  • 5 558 tis. Kč
  • 5 522 tis. Kč
  • MZ
Project

Fuctional diversity of hepatitis C virus quasispecies evaluated by high-throughput analysis of IRES elements activities - implications for the therapy (GA301/07/0607)

Hepatitis C has been recognised during past years as one of the most important viral infectious diseases with estimated number of the infected individuals reaching which can further develop to liver cirrhosis and hepatocellular carc...

EB - Genetika a molekulární biologie

  • 2007 - 2009
  • 5 344 tis. Kč
  • 5 344 tis. Kč
  • GA ČR
Project

Disorder of Porphyprin Metabolism in Patients on regular Hemodialysis and its Association with chronic Hepatitis C virus Infection. (IZ3652)

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1996 - 1997
  • 530 tis. Kč
  • 514 tis. Kč
  • MZ
Project

Diagnosis of chronic hepatitis C virus infection by polymerase chain reaction. (IZ2263)

9F - 9

  • 1994 - 1996
  • 389 tis. Kč
  • 532 tis. Kč
  • MZ
Project

Immunohistochemical detection of predictive factors of response to interferon therapy in patients with chronic hepatitis C (NR7814)

Hepatitis C virus (HCV) related alteration of signalling pathways and proteins (Jak-Stat, ERK1/2, NF-kB, MAP, etc.) regulated/activated by interferon (IFN) may lead to resistance to IFN treatment of patients with HCV infection. HCV ...

EB - Genetika a molekulární biologie

  • 2004 - 2006
  • 1 733 tis. Kč
  • 1 618 tis. Kč
  • MZ
Project

Heme Catabolic Pathway in Chronic Hepatitis C (NT13092)

Heme oxygenase (HMOX), an enzyme induced in response to oxidative stress, catalyzes degradation of pro-oxidative heme to carbon monoxide (CO), iron and biliverdin, which is reduced to bilirubin by biliverdin reductase A (BVRA). Hepatic expre...

FP - Ostatní lékařské obory

  • 2012 - 2015
  • 4 323 tis. Kč
  • 4 323 tis. Kč
  • MZ
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