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3 211 (0,195s) •

Project

Rational design of drug delivery systems based on tailored biodegradable polymers using an iterative in silico and experimental approach (GA22-07164S)

) synthesis and characterization of tunable biodegradable polymers, ii) experimental drug–polymer compatibility screening, iii) in silico drug–polymer compatibility prediction as tools fo...

Pharmacology and pharmacy

  • 2022 - 2024
    • •
  • 8 862 tis. Kč
    • •
  • 8 352 tis. Kč
    • •
  • GA ČR
Project

Poly(2-oxazoline)s In silico adjustment of their properties for development of drug-specific delivery systems (GA25-15646S)

to function as versatile platforms for drug delivery systems (DDS). Among these, poly(2-oxazoline)s (POx) have emerged as a promising polymer class due to their biocompatibility, adjustable properties, and adaptability in drug<...

Physical chemistry

  • 2025 - 2027
    • •
  • 12 470 tis. Kč
    • •
  • 11 423 tis. Kč
    • •
  • GA ČR
Project

Polymer conjugates of drugs targeted with specific oligopeptides (GA204/05/2255)

and biological properties of an anti-angiogenic oligopeptide-targeted polymer drug delivery systém intended for site-specific tumor therapy. The proposed polymer drug delivery of the polymer drug...

CD - Makromolekulární chemie

  • 2005 - 2007
    • •
  • 5 421 tis. Kč
    • •
  • 5 421 tis. Kč
    • •
  • GA ČR
Project

Branched and hyperbranched polymer carriers of drugs for local therapy (IAA400500806)

and biological properties of biodegradable branched and hyperbranched polymer anticancer drug drugdelivery system is a versatile system allowing combine passive or active drug targeting to the solid tumor. Increased molecu...

CD - Makromolekulární chemie

  • 2008 - 2011
    • •
  • 6 448 tis. Kč
    • •
  • 6 448 tis. Kč
    • •
  • AV ČR
Project

Novel Generation of Polymer Drug Carrier Systems for Site-specific Therapy (IAA4050201)

in healthy parts of the body. The proposed properties of the drug can be achieved using a synthetic water-soluble polymer carrier which, thanks to his macromolecular character, protectrs the drug form metabolism and fast e...

CD - Makromolekulární chemie

  • 2002 - 2006
    • •
  • 11 639 tis. Kč
    • •
  • 4 846 tis. Kč
    • •
  • AV ČR
Project

Targeted polymer theranostics for advanced site-specific inflammation treatment (GJ19-00956Y)

. The inflammation-targeted polymer theranostics with controlled drug release should improve properties of linear, micelle-forming and star polymer theranostics intended for long-termed therapy and/or simultaneous diagnosis...

Polymer science

  • 2019 - 2022
    • •
  • 5 451 tis. Kč
    • •
  • 4 830 tis. Kč
    • •
  • GA ČR
Project

*Nanofiber membranes utilization for controlled release of active compounds (FR-TI1/436)

, for drugs by incorporation required substances into the polymer solution before electro spinning. Large specific surface of nanofiber polymers considerably increases material and its functionalization by proteolytic enzy...

JP - Průmyslové procesy a zpracování

  • 2009 - 2012
    • •
  • 13 648 tis. Kč
    • •
  • 8 515 tis. Kč
    • •
  • MPO
Project

Tumor-microenvironment responsive nanomedicines as multistage drug delivery systems for experimental therapy of hematologic malignancies (GA19-01417S)

of the described tailored polymer-drug systems is mediated by their highly-pronounced passive linear polymers and increased therapeutic effect of the combination of drug properties of the tailored polymer...

Hematology

  • 2019 - 2021
    • •
  • 7 703 tis. Kč
    • •
  • 7 616 tis. Kč
    • •
  • GA ČR
Project

Nanofibrous drug delivery systems for local cancer treatment (GA16-04863S)

and drug incorporation. The internal structure of nanofibers and polymer-drugThe proposed project aims at the systematic development of the local drug delivery system based on nanofibrous polymer carrier ...

CD - Makromolekulární chemie

  • 2016 - 2018
    • •
  • 7 647 tis. Kč
    • •
  • 7 029 tis. Kč
    • •
  • GA ČR
Project

STIMULI RESPONSIVE NANOCARRIERS FOR HIGHLY EFFICIENT POLYMER THERAPEUTICS (GCP207/12/J030)

polymer-based anti-cancer nanomedicines intended for efficient site-specific therapy are designed as carriers for a combination of cytotoxic drugs and fluorescent or ESR labels versatile system is based on passive drug tar...

CD - Makromolekulární chemie

  • 2012 - 2015
    • •
  • 6 608 tis. Kč
    • •
  • 6 608 tis. Kč
    • •
  • GA ČR
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