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8 (0,048s) •

Project

Acute Stroke Study of Optimized tPA Dosing in Correlation with Artery Status (NS10106)

Subject: The subject of this study is to provide information on the safety and activity of added intravenous tPA dosage as guided by artery status on transcranial sequential dose levels (15 patients per group) of intravenous tPA in ...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2008 - 2011
    • •
  • 2 607 tis. Kč
    • •
  • 2 507 tis. Kč
    • •
  • MZ
Project

In vitro cultivation of Treponema pallidum a new tool to study genetics and pathogen-host interaction of the agent of syphilis (GA23-07021S)

including T. pallidum subspecies pallidum (TPA), the causative agent of syphilis. In 2018, a first report on long-term in vitro multiplication system for TPA using of treponemes and introduce methods of genetic manipulations to

Microbiology

  • 2023 - 2025
    • •
  • 11 047 tis. Kč
    • •
  • 10 951 tis. Kč
    • •
  • GA ČR
Project

plasminogen activator (tPA) and clinical data (NV19-04-00560)

by tissue-type plasminogen activator (tPA) and by plasminogen activator inhibitor-1 (PAI-1). Thus, tPA/PAI-1 axis arbitrates the extracellular pro-BDNF/BDNF ratio will measure pro-BDNF/BDNF and tPA/PAI-1 ratios in serum an...

Neurosciences (including psychophysiology)

  • 2019 - 2023
    • •
  • 6 924 tis. Kč
    • •
  • 6 924 tis. Kč
    • •
  • MZ
Project

Whole genome sequencing in genome and transcriptome analyses of Treponema pathogens (GAP302/12/0574)

The genus Treponema comprises several human uncultivable pathogenic species and subspecies including causative agent of syphilis (T. pallidum ssp. pallidum,TPA), yaws (T. pallidum ssp. pertenue, TPE), endemic syphilis (T. pallidum ssp. endem...

EE - Mikrobiologie, virologie

  • 2012 - 2016
    • •
  • 10 673 tis. Kč
    • •
  • 10 673 tis. Kč
    • •
  • GA ČR
Project

Development of a new typing scheme for syphilis spirochete, Treponema pallidum subsp. pallidum, preferentially targeting proteome differences (NV17-31333A)

Treponema pallidum subsp. pallidum (TPA) is the causative agent of syphilis. More than 10 million of new syphilis cases are diagnosed annually. Two different typing systems were established for molecular characterization of TPA clin...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2017 - 2020
    • •
  • 11 950 tis. Kč
    • •
  • 11 793 tis. Kč
    • •
  • MZ
Project

Studies on acute stimulation and desquamation of the pulmonary vascular endothelium in isolated perfused rat lungs (GA306/99/0649)

thrombomodulin, tissue plasminogen activator (tPA) and its inhibitor (PAI), ansoluble...

ED - Fyziologie

  • 1999 - 2000
    • •
  • 460 tis. Kč
    • •
  • 460 tis. Kč
    • •
  • GA ČR
Project

Determination of tumor mRNA in patients with colorectal carcinoma as a screening and prognostic method using reverse-transcriptase polymerase chain reaction RT-PCR and comparison with traditional tumor markers. (NR7894)

, cytokeratin markers TPA, TPS, thimidinkinasis Tk....

FJ - Chirurgie včetně transplantologie

  • 2004 - 2006
    • •
  • 1 743 tis. Kč
    • •
  • 1 729 tis. Kč
    • •
  • MZ
Project

Study of molecular mechanisms causing v-Myb suppression using proteomics-based approach (GA301/03/1055)

and/or apoptosis in response to extracellular stimuli such as phorbol esters (TPA...

EB - Genetika a molekulární biologie

  • 2003 - 2005
    • •
  • 3 327 tis. Kč
    • •
  • 3 327 tis. Kč
    • •
  • GA ČR
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