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3 266 (0,215s) •

Project

Jiří Kolář Prometheus's Liver – Hybrid Scholarly Edition (GA22-04611S)

unaddressed versions. In the edition’s digital part genetic criticism methodsThe aim of the project is to prepare a critical edition of Jiří Kolář’s book of poetry Prometheova játra (1950) for publication as part of the KH...

Specific literatures

  • 2022 - 2024
    • •
  • 3 441 tis. Kč
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  • 3 441 tis. Kč
    • •
  • GA ČR
Project

Correction of mutations underlying Fanconi anemia by prime editing - a novel therapeutical strategy for patients with inherited bone marrow failure syndromes (NW24-08-00388)

mutation is corrected by gene editing, represents an attractive treatment strategy patients, however, its potential is limited mainly due to the genetic background of the disease, which prevents using traditional editing s...

Hematology

  • 2024 - 2027
    • •
  • 9 868 tis. Kč
    • •
  • 9 868 tis. Kč
    • •
  • MZ
Project

Scholarly Editing From Plan to Publication (GA14-31160S)

of edition, all in connection with conceptions, as represented by the manuals Editor with the concept of genetic criticism and theories that consider the social functions of scholarly editing. The result of the project wil...

AJ - Písemnictví, mas–media, audiovize

  • 2014 - 2018
    • •
  • 1 263 tis. Kč
    • •
  • 1 263 tis. Kč
    • •
  • GA ČR
Project

The role of Trypanosoma brucei RNA binding proteins in mitochondrial transcript processing. (IAA500960705)

/deletion RNA editing. Much research has focused on the core RNA editing machinery. Preliminary data suggest a role in RNA editing and perhaps in other RNA processing the functional genetic tools available in Trypa...

EB - Genetika a molekulární biologie

  • 2007 - 2010
    • •
  • 4 911 tis. Kč
    • •
  • 4 911 tis. Kč
    • •
  • AV ČR
Project

In vitro toxicological comparison of extracts of stressed transgenic and non-transgenic crops (LTC20015)

The aims of this project are: i) High-throughput screening of plant extracts comparing transgenic plant and its counterpart in order to a) evaluate the approaches which were used for genetic manipulation/edition from the toxicologi...

Food and beverages

  • 2020 - 2023
    • •
  • 4 117 tis. Kč
    • •
  • 4 117 tis. Kč
    • •
  • MŠMT
Project

Genetic sources of antiviral resistance in the domestic chicken (QL24010315)

interactions. The ultimate goal is the genetic modification of the chicken genome in vivo and the biotechnological exploitation of the variants found; for this reason, genetic editing......

Husbandry

  • 2024 - 2028
    • •
  • 38 737 tis. Kč
    • •
  • 28 295 tis. Kč
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  • MZe
Project

Genomic approaches towards the improvement of pod shatter resistance in Brassica napus (8JCH1031)

and genome editing (PRC-CZ) • analysis of Czech genetic resources of rapeseed, evaluation and identification of genes associated with target features, exchange of genetic resources pyramiding technology using MAS approach ...

GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming

  • 2019 - 2021
    • •
  • 296 tis. Kč
    • •
  • 296 tis. Kč
    • •
  • MŠMT
Project

Genetic and epigenetic consequences of chromosome editing in Arabidopsis thaliana model plant (GA22-04364S)

Approaches for targeted genome editing are utilized in the plant research with the aim to select prospective phenotypic traits. Using CRISPR/Cas9 system, stable translocations of ends of chromosome arms were introduced in Arabidopsis thalian...

Biochemistry and molecular biology

  • 2022 - 2024
    • •
  • 4 809 tis. Kč
    • •
  • 4 809 tis. Kč
    • •
  • GA ČR
Project

CRISPR-Cas barley genome editing prospective tool for modern breeding (GA17-07805S)

Drought is a major environmental stress factor, which has begun to negatively affect yield of cereal crops. Method of stable genetic barley transformation will be used for novel, very efficient and easy-to-design genome editing by C...

GE - Šlechtění rostlin

  • 2017 - 2021
    • •
  • 7 016 tis. Kč
    • •
  • 6 969 tis. Kč
    • •
  • GA ČR
Project

Cellular and molecular-genetic characterization of selected hereditary defects of erythropoiesis (NV19-07-00412)

This project aims to establish genetic background, etiology and pathogenesis. We propose several approaches (CRISPR/Cas9 editing, induced pluripotent stem cells, zebrafish and mouse model) to unravel the molecular-genetic m...

Hematology

  • 2019 - 2023
    • •
  • 14 136 tis. Kč
    • •
  • 14 046 tis. Kč
    • •
  • MZ
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