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13 (0,096s) •

Project

Synthetic multiepitopic vaccine agains boreliosis intended for veterinary applications (TA01011165)

adjuvans (liposomes, oil adjuvans, alum, synthetic immunomodulators). Selection...

FP - Ostatní lékařské obory

  • 2011 - 2014
    • •
  • 30 472 tis. Kč
    • •
  • 23 463 tis. Kč
    • •
  • TA ČR
Project

Immunostimulatory substances and adjuvants for prophylaxix of farm animals diseases (RE0930950129)

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 1993 - 1995
    • •
  • 880 tis. Kč
    • •
  • 1 760 tis. Kč
    • •
  • MZe
Project

The induction of antiviral immune response after intranasal aplicaton of nanoparticles based vaccine (LTAUSA19003)

The aim of this study is to develop of chitosan-nanoparticles based vaccine against cytomegalovirus for intranasal application and investigation of the immune response on model animals (mice and nonhuman primates) after application in combination wit...

Cell biology

  • 2020 - 2022
    • •
  • 3 012 tis. Kč
    • •
  • 3 012 tis. Kč
    • •
  • MŠMT
Project

Kinetic profiling of glycosidases for synthesis of glycoconjugates (7AMB13FR014)

Synthetic glycoconjugates are attractive: i. as new immunostimulaing adjuvans with a potential in e.g. future anticancer therapy and, ii. in tuberculosis research due to their presence in mycobacterial cell walls. The aim of this project is ...

CE - Biochemie

  • 2013 - 2014
    • •
  • 108 tis. Kč
    • •
  • 108 tis. Kč
    • •
  • MŠMT
Project

Development of new generation of antitumor immunotherapeutics (TA02010760)

of cells involved in the innate anti-cancer immunity and as adjuvans for vaccines...

CC - Organická chemie

  • 2012 - 2015
    • •
  • 28 480 tis. Kč
    • •
  • 17 170 tis. Kč
    • •
  • TA ČR
Project

Improvement of vaccination efficacy by cholinergic anti-inflammatory pathway (LH11023)

The main object of the proposed project is primary investigation. Importance of the cholinergic anti-inflammatory pathway modulation during vaccination process will be researched. The project will investigate whether the compound HI-6 is able to pote...

EC - Imunologie

  • 2011 - 2014
    • •
  • 2 800 tis. Kč
    • •
  • 2 800 tis. Kč
    • •
  • MŠMT
Project

Targeted chemotherapy towards diseases caused by endoparasites (LD15081)

The aims of the project are to investigate the utilization of some silymarin flavonolignans as adjuvans during the treatment of the parasitic diseases and to prepare potential new hybrid drugs with decreased adverse effects. Next aim is to c...

CC - Organická chemie

  • 2015 - 2017
    • •
  • 1 322 tis. Kč
    • •
  • 1 322 tis. Kč
    • •
  • MŠMT
Project

REcombinant TEchnologies for MEDicine (TN02000122)

Establishment of a centre of competence to achieve application potential in the field of recombinant drug preparation through the integration of research centres built within OP RDI/RDE. Building of research platform for the development of the Czech ...

Industrial biotechnology

  • 2023 - 2028
    • •
  • 520 278 tis. Kč
    • •
  • 348 909 tis. Kč
    • •
  • TA ČR
Project

Recombinant E. coli O83 as a live vector for mucosal vaccines (GA523/03/0186)

Bordetella pertussis, which is a potent mucosal adjuvans. The advantage of thisapproachis...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2003 - 2005
    • •
  • 2 588 tis. Kč
    • •
  • 2 588 tis. Kč
    • •
  • GA ČR
Project

Rational design of novel immunomodulators - potential vaccine adjuvans - based on TLR4 ligands (GA15-11776S)

SMIP -small-molecule immunomodulators, their importance lays in the interaction with pathogen recognition receptors (PRR). One of the most important families of PRR is the Toll-like family of receptors. Crystal structure of TLR4, with attached ligand...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2015 - 2017
    • •
  • 3 403 tis. Kč
    • •
  • 3 403 tis. Kč
    • •
  • GA ČR
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