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594 (0,089s) •

Project

Role of free radicals in the regulation of lung inflammation induced by acute and chronic exposure to endotoxin (GA524/06/1197)

dust induced chronic lung inflammations. Reactive oxygen and nitrogen species (RONS epithelial cells. An important feature of chronic lung inflammation is redox sensitive antioxidant defence in lungs as a...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2006 - 2008
    • •
  • 3 101 tis. Kč
    • •
  • 3 101 tis. Kč
    • •
  • GA ČR
Project

Development of final dosage of fibrinolytic substance for aplication in thoracic surgery and pneumology and potencial use for lung fibrosis and empyemas (EG20_321/0024496)

fibrinolytic for use in lung medicine and thoracic surgery. Effective topical treatment for fibrotic lung processes, which are also expected to increase in connection with the COVID 19 pandemic and for chronic purulent inflamma...

Medical engineering

  • 2021 - 2023
    • •
  • 10 936 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MPO
Project

Molecular characteristics of cytokine network(s) in diffuse lung diseases and perspectives of its diagnostic application (NR9037)

Proposal focuses on characterisation of molecular events in diffuse lung diseases, with main interest to the genes involved in inflammatory and fibrotic processes. Study of expression profiles of cytokine gene networks using sensitive real t...

FC - Pneumologie

  • 2006 - 2009
    • •
  • 6 072 tis. Kč
    • •
  • 5 954 tis. Kč
    • •
  • MZ
Project

Non-invasive lung cancer diagnostics using proteomic biomarkers in exhaled breath condensate. (NV16-32318A)

diseases. Finding non-invasive methods for early detection of lung cancer on the background of underlying lung injury (inflammation, smoking, infections, etc.) would-invasive lung cancer screening technique. Toget...

FD - Onkologie a hematologie

  • 2016 - 2019
    • •
  • 11 186 tis. Kč
    • •
  • 11 186 tis. Kč
    • •
  • MZ
Project

Utilisation of measurements of CC16 protein in serum and lavage for the assessment of degree of inflammation in interstitial lung disease (NI5275)

Oriject directed at determination of serum and bronchoalveolar fluid level of pneumoprotein CC16 in patients with interstitial lung disease (sarcoidosis - different stages, Sjogren sy) and in healthy control subjects. Methods: ELISA, latex, ...

EC - Imunologie

  • 1999 - 2001
    • •
  • 274 tis. Kč
    • •
  • 273 tis. Kč
    • •
  • MZ
Project

Study of mediators of fibrotic processes in patients with diffuse lung diseases and their clinical application (NT11117)

1.The project will investigate mRNA & protein expression profile (EP) of selected molecules, related to pro-fibrotic processes in diffuse lung diseases (DLDs). 2. The EP of chemokines, cytokines and other regulatory molecules contributing of...

EC - Imunologie

  • 2010 - 2015
    • •
  • 9 746 tis. Kč
    • •
  • 9 746 tis. Kč
    • •
  • MZ
Project

Immuno-pathogenetic backing data for the fibro-genesis for interstitial pulmonary processes, biomarkers of fibro-genesis (NT13433)

We aim to reveal mechanisms of fibrogenesis in interstitial lung diseases (ILDs (Ashcroft score, myofibroblastic foci, inflammation, PAR-2, TSLP, TGF-beta, CD124, Ying- Yang 1) in lung biopsies of patients with ILDs, with m...

FC - Pneumologie

  • 2012 - 2014
    • •
  • 3 142 tis. Kč
    • •
  • 3 142 tis. Kč
    • •
  • MZ
Project

Functional heterogeneity of porcine mononuclear phagocytes during experimentally induced lung inflammation by Actinobacillus pleuropneumoniae (GPP502/10/P362)

in a model of experimentally induced lung inflammation after Actinobacillus...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2010 - 2012
    • •
  • 1 500 tis. Kč
    • •
  • 1 500 tis. Kč
    • •
  • GA ČR
Project

E. COLI O83 IN THE PREVENTION OF THE POLY-SENSITIZATION IN CONVENTIONAL AND GNOTOBIOTIC MOUSE MODEL OF POLLEN ALLERGY (8J20AT011)

to modulate allergic poly-sensitization and allergic lung inflammation (CZ, analysis to prevent allergic poly-sensitization and allergic lung inflammation (A, analysis......

Microbiology

  • 2020 - 2022
    • •
  • 156 tis. Kč
    • •
  • 156 tis. Kč
    • •
  • MŠMT
Project

Introduction of novel diagnostic and monitoring approaches to the early stages of chronic suppurative lung disease in children (NW25-07-00214)

Chronic suppurative lung disease (CSLD) encompasses a group of progressive respiratory tract disorders characterized by prolonged airway infection and inflammation dyskinesia indicate early origin of lung function and struc...

Paediatrics

  • 2025 - 2028
    • •
  • 9 934 tis. Kč
    • •
  • 9 934 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 594