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47 (0,119s) •

Project

High stored iron levels and endothelial dysfunction. (NA6124)

The aim of the study is to clarify if high stored iron levels do have any association with the progression of atherosclerosis in the aortic arch arteries measured by the endothelium dependent vasodilation of the brachial artery.......

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2000 - 2002
    • •
  • 2 133 tis. Kč
    • •
  • 2 132 tis. Kč
    • •
  • MZ
Project

Influence of some lymphocyte subpopulations and markers of thrombocyte activation to the clinical progress of preeclampsia (NR8906)

The objective of this project is to determine expression of some subpopulations of lymphocytes which influence the damage of endothelium and markers of thrombocyte activation and their influance om the degree of preeclampsia.......

FK - Gynekologie a porodnictví

  • 2006 - 2008
    • •
  • 1 804 tis. Kč
    • •
  • 1 703 tis. Kč
    • •
  • MZ
Project

Influence on preservating medias to the quality of corneal grafts after penetrating keratoplasty (NK7729)

Time factor significance of preservation medium - cell culture - enabling preservation of corneas for a longer period than in usual preservation medium - Optisol. Quality estimation of endothelial cells in corneas preserved in cell culture. Compariso...

FF - ORL, oftalmologie, stomatologie

  • 2003 - 2005
    • •
  • 2 295 tis. Kč
    • •
  • 2 051 tis. Kč
    • •
  • MZ
Project

The role of oxidative stress in pathogenesis of diabetic angiopathy and the possibilities of pharmacological intervention. (IZ4271)

The role of oxidative stress in development of early stages of vascular changes in diabetic patients will be determined together with the effect of glycosaminoglycan sulodexide treatment in patients with endothelium activation.......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1997 - 1999
    • •
  • 611 tis. Kč
    • •
  • 611 tis. Kč
    • •
  • MZ
Project

Posterior polymorphous corneal dystrophy molecular, cellilar and clinical characteristic (GA301/03/1040)

Posterior polymorphous corneal dystrophy (PPCD) is a disorder of the cornea with autosomal dominant inheritance clinically characterized by alterations of endothelium and Descemet's membrane. The severity of the disorder varies and can lead ...

FF - ORL, oftalmologie, stomatologie

  • 2003 - 2005
    • •
  • 3 600 tis. Kč
    • •
  • 3 600 tis. Kč
    • •
  • GA ČR
Project

Importance of the interaction of myeloperoxidase with the endothelial glycocalyx for leukocyte recruitment and vascular fuction (GCP305/12/J038)

endothelium functions. The objective is to characterize to which extent MPO modulates, and ultimately modulates endothelium permeability, recruitment of leukocytes......

EB - Genetika a molekulární biologie

  • 2012 - 2016
    • •
  • 4 488 tis. Kč
    • •
  • 4 488 tis. Kč
    • •
  • GA ČR
Project

Studies on acute stimulation and desquamation of the pulmonary vascular endothelium in isolated perfused rat lungs (GA306/99/0649)

Acute stimulation of the pulmonary endothelium in acute lung injury caused by various stimuli leads to the release of different mediators and soluble endothelial receptors. Endothelial shedding and formation of endothelial microparticles ver...

ED - Fyziologie

  • 1999 - 2000
    • •
  • 460 tis. Kč
    • •
  • 460 tis. Kč
    • •
  • GA ČR
Project

The role of mitochondrial bioenergetics in the resistance of quiescent cells to oxidative stress (GA16-22823S)

to the targeted loss of mitochondrial DNA and ETC activity in the endothelium. In this model, we will examine the sensitivity of angiogenic and quiescent endothelium to ROS......

EB - Genetika a molekulární biologie

  • 2016 - 2018
    • •
  • 7 062 tis. Kč
    • •
  • 7 008 tis. Kč
    • •
  • GA ČR
Project

Tissue and soluble endoglin and their importance in endothelial dysfunction and atherogenesis in vivo and in vitro (GA15-24015S)

Endoglin is a TGF-β receptor III, which is important for the function of endothelium, and its tissue and soluble form was detected in atherosclerosis. Endoglin role with respect to endothelial function/dysfunction and atherogenesis to affect...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2015 - 2017
    • •
  • 5 760 tis. Kč
    • •
  • 5 760 tis. Kč
    • •
  • GA ČR
Project

Assessment of the Prognosis and the Incidence of Complication in Sclerotic and Diabetic Angiopathy of Vessels of the Lower Limbs. (NA6408)

The authors will perform a complete clinical examination, a morphological and a functional assessment of the vascular wall, an examination of thrombolytic activity parameters, of fibrin degradation products, and of adhesive molecules. The groups of a...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2000 - 2002
    • •
  • 2 523 tis. Kč
    • •
  • 2 522 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 47