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9 (0,221s) •

Project

Telomere biology of trypanosomatids contrasting features point to diverse strategies (GA23-04769S)

Although our knowledge of telomere biology in trypanosomatids is relatively advanced (at least in the main model species, T. brucei), recent studies in a wider range of related species, including our own published and preliminary results show a numbe...

Cell biology

  • 2023 - 2025
    • •
  • 12 512 tis. Kč
    • •
  • 12 303 tis. Kč
    • •
  • GA ČR
Project

RNA editing in non-model flagellates (GA22-01026S)

Armed with new tools to analyze canonical and non-canonical RNA editing at the level of singular events, we will study this process in non-model trypanosomatids and other euglenozoans. In addition, we propose to scrutinize the structure of kinetoplas...

Biochemistry and molecular biology

  • 2022 - 2024
    • •
  • 9 432 tis. Kč
    • •
  • 8 906 tis. Kč
    • •
  • GA ČR
Project

Trypanosomatid biochemistry an insight from the neglected groups (LUASK22033)

Family Trypanosomatidae is a species-rich group of protists parasitizing a wide range of hosts. Several genera are pathogenic to vertebrates, animals, and plants and, thus, they are attractive for research and we have acquired a substantial ...

Biochemistry and molecular biology

  • 2022 - 2025
    • •
  • 3 101 tis. Kč
    • •
  • 3 101 tis. Kč
    • •
  • MŠMT
Project

Phlebotomus orientalis salivary proteins and the host antibody response (GA13-05292S)

Sand flies (Diptera: Phlebotominae) are bloodfeeding insects and vectors of Leishmania parasites (Kinetoplastida: Trypanosomatidae), the causative agents of leishmaniases. During bloodfeeding, sand flies inject saliva into the host skin. The...

EG - Zoologie

  • 2013 - 2016
    • •
  • 6 935 tis. Kč
    • •
  • 6 935 tis. Kč
    • •
  • GA ČR
Project

Viruses of trypanosomatids maintenance and transmission (GA24-10009S)

The current proposal aims to investigate diverse viruses of trypanosomatids, but the main focus of the project will be on Leishmania RNA viruses (LRVs), which are implicated in the control of leishmaniasis severity. The disease remains a public healt...

Infectious Diseases

  • 2024 - 2026
    • •
  • 7 781 tis. Kč
    • •
  • 7 556 tis. Kč
    • •
  • GA ČR
Project

Vývoj a pohlavní rozmnožování Leishmania donovani v různých druzích flebotomů. (GA13-07500S)

Leishmaniases are human diseases transmitted by sand flies (Diptera: Psychodidae) with a wide spectrum of clinical manifestations; visceral disease caused by Leishmania donovani (Kinetoplastida: Trypanosomatidae) being even fatal. The proje...

EG - Zoologie

  • 2013 - 2016
    • •
  • 7 199 tis. Kč
    • •
  • 7 199 tis. Kč
    • •
  • GA ČR
Project

Catalase to be or not to be in two hosts (GA21-09283S)

Parasitism is an extremely successful lifestyle that involves a variety of strategies to utilize one or more hosts. In this grant proposal, we propose to investigate a medically important group of trypanosomatids (Leishmaniinae), which includes both ...

Microbiology

  • 2021 - 2023
    • •
  • 8 731 tis. Kč
    • •
  • 8 402 tis. Kč
    • •
  • GA ČR
Project

Hidden in the honeycomb Microsporidian and trypanosomatid parasites in bees identified by metabarcoding approach (GA25-16047S)

We aim to investigate the diversity of microsporidian and trypanosomatid parasites in bees, with a focus on wild species, an area that has been overlooked in previous research. We will combine microscopic and cultivation methods with modern molecular...

Parasitology

  • 2025 - 2027
    • •
  • 12 506 tis. Kč
    • •
  • 12 506 tis. Kč
    • •
  • GA ČR
Project

Vliv hmyzího přenašeče na projevy onemocnění působeného Leishmania infantum (GA206/09/0777)

Leishmaniases are vector-borne diseases with a wide spectrum of clinical forms. Their causative agents, protozoans of the genus Leishmania (Kinetoplastida: Trypanosomatidae), are transmitted by phlebotomine sand flies (Diptera: Psychodidae)....

EG - Zoologie

  • 2009 - 2012
    • •
  • 4 477 tis. Kč
    • •
  • 4 477 tis. Kč
    • •
  • GA ČR
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