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3 073 (0,076s) •

Project

Genetic and epigenetic predictive biomarkers of treatment success for angiogenesis inhibitors in colorectal carcinoma (NV16-32198A)

, validated predictive biomarkers are seeked for. This project aims to bring new biomarkers for potentially predictive biomarkers to antiVEGF (bevacizumab) treatment, chosen based on online cancer genome ...

FD - Onkologie a hematologie

  • 2016 - 2019
    • •
  • 9 824 tis. Kč
    • •
  • 8 867 tis. Kč
    • •
  • MZ
Project

Identification of new diagnostic/predictive biomarkers and compounds applicable to personalized treatments of multidrug resistant tumors (LTC19020)

The aim of this project is identification and validation of new prognostic and predictive molecular biomarkers of multidrug resistence in solid tumors. New molecular biomarkers will be characterized in detail by analysis o...

Human genetics

  • 2019 - 2022
    • •
  • 3 936 tis. Kč
    • •
  • 3 936 tis. Kč
    • •
  • MŠMT
Project

Identification of novel biomarkers panels in selected malignancies (FR-TI3/666)

biomarkers for earlier detection and prediction of prognosis in oncological diseases will then assess the specificity and sensitivity of every single biomarker in relation to diagnosis or prognosis prediction. Fif...

FD - Onkologie a hematologie

  • 2011 - 2014
    • •
  • 26 530 tis. Kč
    • •
  • 20 138 tis. Kč
    • •
  • MPO
Project

Mapping of glioma heterogeneity and infiltration extend by MR imaging biomarkers (LTC20027)

The objectives of this INTER-COST project are to verify whether segmentation of gliomas based on different MRI biomarkers match each other and the results can mark analysis of multiparametric MRI is able to provide predictive spatia...

Clinical neurology

  • 2020 - 2023
    • •
  • 4 489 tis. Kč
    • •
  • 4 489 tis. Kč
    • •
  • MŠMT
Project

Study of prognostic and predictive biomarkers in the treatment of pancreatic cancer (NV16-28375A)

The motive of this multidisciplinary research project is to obtain new knowledge in the field of predictive and prognostic biomarkers of pancreatic cancer. Partial aim is also to evaluate the mechanism of action of validated bio...

FD - Onkologie a hematologie

  • 2016 - 2019
    • •
  • 10 698 tis. Kč
    • •
  • 10 469 tis. Kč
    • •
  • MZ
Project

Plasma EBV-DNA as a biomarker of treatment for EBV-positive Hodgkin's lymphoma and its predictive value for outcome (NR9166)

By means of new biological predictive marker individualize therapy of Hodgkin's lymphoma aiming at reduction of treatment toxicity without jeopardizing the effectiveness. Plasma EBV-DNA as a non-invasive biomarker in EBV-positive Ho...

FD - Onkologie a hematologie

  • 2007 - 2009
    • •
  • 3 470 tis. Kč
    • •
  • 3 449 tis. Kč
    • •
  • MZ
Project

Development of microRNA-based biomarkers for diagnostics of cancer chemoresistance (TH04010303)

The goal of the project is identification of new generation of microRNA-based biomarkers and their use for early diagnosis of certain types of cancer and prediction represent a unique group of biomarkers with a great diagno...

Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])

  • 2019 - 2021
    • •
  • 9 748 tis. Kč
    • •
  • 5 630 tis. Kč
    • •
  • TA ČR
Project

Study of apoptosis inhibitors as diagnostic and predictive tumor biomarkers in lung cancer (NR7860)

Analysis of expression of apoptosis inhibitors by molecular and biochemical methods in tumor tissue, lung parenchyma, biopsy and cytological samples and sputum from lung cancer patients and study of their significance as tumor biomarkers in ...

FD - Onkologie a hematologie

  • 2004 - 2008
    • •
  • 9 173 tis. Kč
    • •
  • 8 553 tis. Kč
    • •
  • MZ
Project

Human urinary exosomes - the source of new biomarkers for the diagnosis and follow-up of kidney diseases (NV15-31662A)

The project will study new diagnostic and predictive biomarkers in urinary and expression analysis of microRNAs will be used to determine specific biomarkers. These biomarkers will be measured in patients during va...

FE - Ostatní obory vnitřního lékařství

  • 2015 - 2019
    • •
  • 7 500 tis. Kč
    • •
  • 7 441 tis. Kč
    • •
  • MZ
Project

Candidate biomarkers of resistance to retinoids in children with high-risk neuroblastoma (NV15-34621A)

help to identify useful predictive biomarkers of the patient’s response candidate biomarkers (PBX1, HOXC9, NF1, HMGI-C and HMGA2) associated with the resistance to retinoids in neuroblastoma cells. Endogenous expression of...

FG - Pediatrie

  • 2015 - 2018
    • •
  • 7 309 tis. Kč
    • •
  • 7 309 tis. Kč
    • •
  • MZ
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