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106 (0,064s) •

Project

Hippocampal involvement in neocortical epilepsy networks Implications for surgical planning (NU21J-08-00081)

of patients with focal epilepsy, whose hippocampal formation is likely involved in seizures (Focal Cortical Dysplasia IIIa, dual pathology with hippocampal sclerosis hippocampal resection were more likely to have ...

Clinical neurology

  • 2021 - 2024
    • •
  • 6 706 tis. Kč
    • •
  • 6 706 tis. Kč
    • •
  • MZ
Project

Damage of interneurons within the hippocampus and dentate gyrus after status epilepticus in developing rats (GA304/04/0464)

Temporal lobe epilepsy represents majority of therapy-resistant epilepsies in patients. Many cases start during childhood. This epilepsy is characterized morphologically by hippocampanal sclerosis affecting mostly dentate gyrus and hippo...

EA - Morfologické obory a cytologie

  • 2004 - 2006
    • •
  • 2 715 tis. Kč
    • •
  • 2 715 tis. Kč
    • •
  • GA ČR
Project

The role of neurodegeneration in pathogenesis, manifestations and prognosis of MTLE/HS - in vivo, ex vivo and in vitro perspective (NU22-04-00366)

epilepsy with hippocampal sclerosis (MTLE/HS) from three world-class epilepsy centers...

Neurosciences (including psychophysiology)

  • 2022 - 2025
    • •
  • 10 693 tis. Kč
    • •
  • 10 693 tis. Kč
    • •
  • MZ
Project

Neuropathological analysis of human epileptic brain tissue correlation with proton magnetic resonance spectroscopy. (NF7411)

Brain tissue from temporal lobectomies of refractory epileptic patients will be analysed using advanced histological, immunohistochemical, and fluorescent techniques. The project will be focused on detecting abnormalities of inhibitory GABAergic syst...

FH - Neurologie, neurochirurgie, neurovědy

  • 2003 - 2005
    • •
  • 4 304 tis. Kč
    • •
  • 3 970 tis. Kč
    • •
  • MZ
Project

Proton Magnetic Resonance Spectroscopy Correlation with Neuropathological Findings in Patients with Mesial Temporal Lobe Epilepsy (GP309/02/D076)

MRIfinding of hippocampal sclerosis. This problem can only be solved by thorough...

FH - Neurologie, neurochirurgie, neurovědy

  • 2002 - 2005
    • •
  • 846 tis. Kč
    • •
  • 846 tis. Kč
    • •
  • GA ČR
Project

Cytokines in relationship to immunoglobulin production in multiple sclerosis. (IZ2777)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1995 - 1997
    • •
  • 1 155 tis. Kč
    • •
  • 1 155 tis. Kč
    • •
  • MZ
Project

Hippocampal impairment in schizophrenia proton magnetic resonance spectroscopy study and dermatoglyphic analysis (NF6794)

By means of magnetic resonance spectroscopy and dermatoglyphic analysis we will elucidate the relationship between prenatal events pior the end of the second trimester of gestation and hippocampal impairment in schizophrenia. We will compare...

FH - Neurologie, neurochirurgie, neurovědy

  • 2001 - 2003
    • •
  • 2 316 tis. Kč
    • •
  • 2 285 tis. Kč
    • •
  • MZ
Project

Reaction of hippocampal neuronal population on stereotactic radiotherapy of extratemporal brain metastases The influence on the neurocognitive function and maintanance of quality of life (NV18-03-00469)

proved bad impact of conventional whole brain irradiation on hippocampal N-acetylaspartate concentrations and parallel decline in verbal memory. Decrease in hippocampal focusing on hippocampal changes and neurocognitive im...

Oncology

  • 2018 - 2023
    • •
  • 7 086 tis. Kč
    • •
  • 6 999 tis. Kč
    • •
  • MZ
Project

The development of lower urinary tract dysfunction in remittent form of multiple sclerosis on dependency of neurological treatment. (NR8188)

The prospective study of development of lower urinary tract dysfunction in patients treated by drugs of the first choice for remittent stadium of multiple sclerosis (interferons) and the patients treated by combine immunosuppressives.......

FH - Neurologie, neurochirurgie, neurovědy

  • 2004 - 2006
    • •
  • 1 999 tis. Kč
    • •
  • 1 569 tis. Kč
    • •
  • MZ
Project

Osteoporosis in multiple sclerosis patients the impact of corticosteroids and immobility on its development, possibilities and therapy (NF6780)

Osteodensitometric and laboratory examinations of multiple sclerosis patientsfollowed in MS Center will be carried out to determine the exte of osteopenia and osteoporosis to establish the impact of steroid therapy on increased bone fragilit...

FH - Neurologie, neurochirurgie, neurovědy

  • 2001 - 2003
    • •
  • 2 748 tis. Kč
    • •
  • 2 712 tis. Kč
    • •
  • MZ
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