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10 955 (0,153s) •

Project

Complexes of selected transition metals with plant-derived compounds with anti-NF-kappa B and pro-PPAR dual activities (GF21-38204L)

effect during exposure of HUVEC cells to TNFα. In vivo anti-inflammatory effects problem.Promising approach to manage inflammatory processes is the modulation of activity of pro-inflammatory tran...

Inorganic and nuclear chemistry

  • 2021 - 2023
    • •
  • 9 028 tis. Kč
    • •
  • 9 028 tis. Kč
    • •
  • GA ČR
Project

Anti-inflammatory properties of bioactive compounds isolated from Cannabis sativa L. (GA22-20860S)

a unique group of compounds showing numerous health beneficial biological effects, including the anti-inflammatory one. At the same time, the low-grade inflammation cannabis plants, and investigate their single and combine...

Food and beverages

  • 2022 - 2024
    • •
  • 12 342 tis. Kč
    • •
  • 11 490 tis. Kč
    • •
  • GA ČR
Project

Natural bioactive compounds encapsulated in glucan microparticles as biomaterials suitable in the treatment of inflammatory bowel diseases (NV16-27522A)

amplification of anti-inflammatory effect as well. Based on previous in vivo and clinical of utilization the glucan microparticles as vectors of these anti-inflammatory compoundsInflammatory Bowe...

FR - Farmakologie a lékárnická chemie

  • 2016 - 2019
    • •
  • 10 350 tis. Kč
    • •
  • 10 350 tis. Kč
    • •
  • MZ
Project

Role of prenylation and glycosylation patterns in anti-inflammatory activity and metabolism of natural phenolic compounds (GA23-04655S)

of prenylated and/or glycosylated phenols, monitor their effect on the colon microbiota, their metabolism in intestinal models and test pro- and antioxidant, anti-inflammatory in a wide range of foods and medicinal plants....

Plant sciences, botany

  • 2023 - 2025
    • •
  • 13 963 tis. Kč
    • •
  • 13 963 tis. Kč
    • •
  • GA ČR
Project

Changes of expression of pro-inflammatory enzymes caused by isoquinoline alkaloids during differentiation of promyelocytes into neutrophils (GP303/06/P193)

This project is designed to study possible mechanisms of anti-inflammatory effects and to detect side effects of sanguinarine, chelerythrine, berberine, protopine, and colchicine, all alkaloids displaying anti<...

CE - Biochemie

  • 2006 - 2008
    • •
  • 1 044 tis. Kč
    • •
  • 1 044 tis. Kč
    • •
  • GA ČR
Project

Anti-inflammatory activity of extracts isolated from selected Indonesian plants and their effect on opportunistic parasitoses (GAP505/11/1163)

Main aim of proposed project is the identification of biological active compounds with potential anti-inflamatory and antiparasitic effect from plant diet of wild orang-utans at Sumatra and Kalimantan. Selected compounds will be tes...

EF - Botanika

  • 2011 - 2015
    • •
  • 12 797 tis. Kč
    • •
  • 12 797 tis. Kč
    • •
  • GA ČR
Project

Anti-inflammatory effects of novel lipokines of fatty acid esters of hydroxy fatty acids family in obesity (GJ17-10088Y)

acid with anti-inflammatory and anti-diabetic properties was discovered. Our hypothesis is that novel FAHFAs derived from omega-3 PUFA, with anti-inflammatory and exert beneficial metabolic effects

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2017 - 2019
    • •
  • 5 609 tis. Kč
    • •
  • 5 609 tis. Kč
    • •
  • GA ČR
Project

The influence of anti-inflamatory agents in combination with mesenchymal stem cells on the development of traumatic spinal cord lesions in the rat (GP13-15031P)

that the combination of cell transplantation and anti-inflammatory agents could be a more effective injury using anti-inflammatory agents. Subsequently, we would like to transplant the entire personal int...

FH - Neurologie, neurochirurgie, neurovědy

  • 2013 - 2015
    • •
  • 2 740 tis. Kč
    • •
  • 2 740 tis. Kč
    • •
  • GA ČR
Project

Production of Dendrobium candidum biomass in vitro and study its biological activity (LH12164)

The project aims are: a) production of Dendrobium candidum biomass by callus and cell cultures b) assess anti-inflammatory (cyclooxygenase-1 and -2 and 5-lipoxygense inhibition) and anti-oxidative activity (by DPPH and ORAC...

EI - Biotechnologie a bionika

  • 2012 - 2013
    • •
  • 1 440 tis. Kč
    • •
  • 1 440 tis. Kč
    • •
  • MŠMT
Project

Determining the molecular aspects of spinal cord injury, regeneration, stem cell therapy and treatment with anti-inflammatory compounds (LH12024)

To assess the molecular mechanisms underlying spinal cord injury and regeneration after cell therapy and/or anti-inflammatory treatment. To determine the levels of cytokines and growth factors and molecular markers associated with S...

FH - Neurologie, neurochirurgie, neurovědy

  • 2012 - 2015
    • •
  • 3 179 tis. Kč
    • •
  • 3 179 tis. Kč
    • •
  • MŠMT
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