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3 (0,087s)

Project

Labelling of monoclonal antibodies with At-211 for targeted cancer therapy (KJB4048302)

Radionuclide AT-211 is one of a few promising alpha emitters for targeted therapy of tumours, which cannot be treated by other methods. Cyclotron U-120M that are capable to produce At-211 in sufficient amount and quality. The propos...

CH - Jaderná a kvantová chemie, fotochemie

  • 2003 - 2005
  • 1 656 tis. Kč
  • 1 336 tis. Kč
  • AV ČR
Project

Thermoresponsive polymeric drug delivery systems for local radiotherapy (IAA400480616)

Thermoresponsive polymers are prospective systems for medical applications. One of them might be radiotherapy of joint inflammations or tumours with a thermoresponsive polymer labelled with a suitable radionuclide. These polymers are namely well solu...

CD - Makromolekulární chemie

  • 2006 - 2008
  • 3 965 tis. Kč
  • 3 965 tis. Kč
  • AV ČR
Project

Preparation of new radiopharmaceuticals based on monoclonal and recombinant antibodies and peptides labelled by alpha and beta radionuclides (IBS1048301)

A. Choice of approppriate monoclonal antibodies (MABs) and their scFv fragments. The following MABs and their fragments will be examined in the first step: TU-20, an antibody against neuron-specific tubuline, MEM-97, an antibody specific for leukocyt...

CH - Jaderná a kvantová chemie, fotochemie

  • 2003 - 2005
  • 7 375 tis. Kč
  • 3 731 tis. Kč
  • AV ČR
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