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A role of hereditary mutations of the PALB2 gene in breast, ovarian and pancreatic cancer development in the Czech Republic (NT14006)
The subject of this project is analysis of the PALB2 gene role in a pathogenesis of breast, ovarian and pancreatic carcinoma in the Czech Republic. We and hypermethylation of promoter region will be studied in samples with identified PAL...
FD - Onkologie a hematologie
- 2013 - 2015 •
- 4 440 tis. Kč •
- 4 440 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2013 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
HEREDITARY BREAST AND OVARIAN CANCER THE ROLE OF LOW PENETRANCE GENES IN TUMORIGENESIS (NS10304)
The aim of our project is to evaluate the effect of low penetrance genes on breast and ovarian cancer development in the Czech Republic in high-risk patients tested negatively for major susceptibility genes (BRCA1/2) Mutation analysis of low penetran...
FD - Onkologie a hematologie
- 2009 - 2011 •
- 5 456 tis. Kč •
- 5 456 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2009 - 31. 12. 2011
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Classification of variants of unknown significance in cancer susceptibility genes by the multiplex PCR/NGS-based analysis of their impact on pre-mRNA splicing (NV18-03-00024)
of VUS in genes predisposing to breast and ovarian cancer (CHEK2, PALB2, NBN, TP53...
Genetics and heredity (medical genetics to be 3)
- 2018 - 2021 •
- 9 940 tis. Kč •
- 9 775 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2018 - 31. 12. 2021
Uznané náklady
Podpora ze státního rozpočtu (98%)
Poskytovatel: Ministerstvo zdravotnictví
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