Filters
The chaperones and stress factors effect on folding and stability of the wild type and mutant cystathionine beta-synthase (CBS) (GP305/02/D167)
. Wewillexpress wild type and mutant CBS fused with green fluorescent protein in CHO cells. WeThe balance between synthesis and degradation determines the steady-state level of given protein in a cell. The fate of the mutan...
EB - Genetika a molekulární biologie
- 2002 - 2004 •
- 580 tis. Kč •
- 580 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2002 - 1. 1. 2004
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Recombinant antibody molecules for in vivo imaging and therapy of prostate cancer (LTAUSA18196)
in CHO/HEK293 cells 6) use of mAb derivatives for in vivo imaging in mouse model...
Health-related biotechnology
- 2019 - 2022 •
- 5 437 tis. Kč •
- 5 437 tis. Kč •
- MŠMT
Řešení projektu: 1. 1. 2019 - 31. 12. 2022
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
Effect of ethanol and its principle metabolite acetaldehyde on cardiac inward rectifier potassium currents a link to atrial fibrillation related to alcohol consumption? (NT14301)
of the effect of ethanol and acetaldehyde on IK1 and IK(Ach) by whole cell patch clamp expressed in Chinese Hamster Ovary cells. Using mathematical models of rat, guinea pig......
FA - Kardiovaskulární nemoci včetně kardiochirurgie
- 2013 - 2015 •
- 3 369 tis. Kč •
- 3 229 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2013 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (96%)
Poskytovatel: Ministerstvo zdravotnictví
Clinical significance and electrophysiological evaluation of KCNQ1 gene mutation c.926C>T (p.T309I) as a possible long QT syndrome founder mutation (NV16-30571A)
analysis in wild type and mutant human IKs channels expressed in CHO cells, and mathematical simulations in a human ventricular cell model. These data will allow us......
FA - Kardiovaskulární nemoci včetně kardiochirurgie
- 2016 - 2020 •
- 10 413 tis. Kč •
- 10 381 tis. Kč •
- MZ
Řešení projektu: 1. 4. 2016 - 31. 12. 2020
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Cytosolic and membrane-bound forms of trimeric GTP-binding proteins in desensitization of beta-adrenergic stimulus (GA305/96/0678)
The role of membrane-bound and soluble (cytosolic) forms of the alpha subunits of GTP-binding proteins in desensitization of beta-adrenergic stimulation of brown and white adipose tissue (atypical, beta 3-adrenoceptors) and heart muscle (beta 1) will...
CE - Biochemie
- 1996 - 1998 •
- 1 285 tis. Kč •
- 1 285 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 1996 - 1. 1. 1998
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Mechanisms of disruption of cell-to-cell communication and regulation of cell proliferation in liver cells (GA524/06/0517)
The project aims to is to contribute to understanding of regulation of cell-to-cell communication and proliferation in liver oval cells that are sensitive both of WB-F344 rat liver epithelial cells will be introduc...
ED - Fyziologie
- 2006 - 2008 •
- 3 007 tis. Kč •
- 3 007 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2006 - 31. 12. 2008
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Growth and cell cycle - mechanisms of mutual coordination (GA15-09231S)
The cell cycle progression is intricately intertwined with cell growth. In green algae dividing by multiple fission a critical cell size is a prerequisite regulatory point required for the cell cycle entry. Once CP...
EE - Mikrobiologie, virologie
- 2015 - 2019 •
- 5 639 tis. Kč •
- 5 639 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2015 - 29. 11. 2019
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Deciphering pancreas development and function at the single-cell level (GA25-15876S)
Understanding the embryonic development of the pancreas, particularly cell fate decisions, endocrine cell differentiation, and functional maturation of endocrine cells for replacing dysfunctional β cells. Our previ...
Developmental biology
- 2025 - 2027 •
- 11 748 tis. Kč •
- 11 748 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2025 - 31. 12. 2027
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
The relationship between cell size and the size of cellular organelles during early embryonic development in mammals (GA19-24528S)
Despite current progress in cell biology the mechanism how cells maintain conditions are characterized by changes in cell sizes. A maintenance of cell volume cells are actually measuring their volume. Prel...
Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)
- 2019 - 2022 •
- 7 954 tis. Kč •
- 7 588 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2019 - 30. 6. 2022
Uznané náklady
Podpora ze státního rozpočtu (95%)
Poskytovatel: Grantová agentura České republiky
Cell cycle regulation in human embryonic stem cells - study toward establishing identifiable characteristics of high quality cells (GA301/05/0463)
Many aspects of the biology of human embryonic stem (hES) cells must be understood before any therapeutical application of this cell type is possible. Compromised ability to withdraw from cell cycle often results in uncontr...
EI - Biotechnologie a bionika
- 2005 - 2007 •
- 2 918 tis. Kč •
- 2 918 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2005 - 31. 12. 2007
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
- 1 - 10 out of 4 862