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238 (0,082s) •

Project

Stress granules assembly on yeast mitochondria (MEB060902)

The main goal of the project is to elucidate the function of the stress granule interaction with mitochondria in stressed yeast S.cerevisiae.......

CE - Biochemie

  • 2009 - 2010
    • •
  • 76 tis. Kč
    • •
  • 76 tis. Kč
    • •
  • MŠMT
Project

Interaction of Mmi1/TCTP protein with mitochondria (LUASK22100)

and detection of TCTP on model human cell line Hep2 or HeLa. c) Izolation of mitochondria of physiological state of mitochondria during Mmi1/TCTP binding by: a) Measurement of mitochondria respiration. b) Measurment of ...

Cell biology

  • 2022 - 2025
    • •
  • 3 096 tis. Kč
    • •
  • 3 096 tis. Kč
    • •
  • MŠMT
Project

Role of receptor tyrosine kinase Her2 in mitochondria (GA16-12719S)

that it is localised to large extent in mitochondria in relevant cancer cells, which is for the receptor tyrosine kinase highly unexpected. The function of Her2 in mitochondria detailed aspects of the function of Her2 in mitoch...

EB - Genetika a molekulární biologie

  • 2016 - 2018
    • •
  • 6 654 tis. Kč
    • •
  • 6 543 tis. Kč
    • •
  • GA ČR
Project

Searching for evidence of the secondary loss of mitochondria in oxymonads (GA204/03/1243)

understood. Whether mitochondria originated simultaneously with the origin of eukaryotic of anaerobic protozoa lack mitochondria the absence of this organelle can be a secondary thepossibility, that in some cases the ancestors of t...

EB - Genetika a molekulární biologie

  • 2003 - 2005
    • •
  • 3 050 tis. Kč
    • •
  • 2 352 tis. Kč
    • •
  • GA ČR
Project

Evolutionary adaptation of the inner membrane protein translocase to the loss of membrane potential in anaerobic mitochondria-like organelles (LUABA22082)

1. Bioinformatic and in silico structural comparison of the core TIM23 subunits from mitochondria and MROs that lack the membrane potential 2. Bioinformatic and functional comparisons of targeting presequences of mitochondrial and mitosomal...

Cell biology

  • 2022 - 2024
    • •
  • 1 200 tis. Kč
    • •
  • 1 200 tis. Kč
    • •
  • MŠMT
Project

Evolution and biogenesis of mitochondria-related organelles hydrogenosomes and mitosomes (IAA501110631)

Mitochondria are archetypal organelles of endosymbiotic origin in eukaryotic be common with mitochondria. More recently, in giardia, double membrane-bound organelles named mitosomes were discovered, which may represent highly reduce...

EE - Mikrobiologie, virologie

  • 2006 - 2009
    • •
  • 3 577 tis. Kč
    • •
  • 3 577 tis. Kč
    • •
  • AV ČR
Project

The evolution of mitochondrial biogenesis. (GAP305/10/0651)

Mitochondria stand outside the secretory pathway and as such they contain a set unicellular eukaryotes. We study the biogenesis of the simplest mitochondria found yet functional differences in these simple mitochondria, whi...

EB - Genetika a molekulární biologie

  • 2010 - 2014
    • •
  • 4 789 tis. Kč
    • •
  • 4 789 tis. Kč
    • •
  • GA ČR
Project

Elucidation of the mechanism of flavonoid-dependent cardioprotection and changes in the bioenergetic status of the cell (GAP301/11/0662)

cytoprotective activity and have been linked to cardioprotection. Mitochondria are central ? dependent cytoprotection and mitochondria is virtually unknown. The long term goal mitochondria directly or indirectly through mu...

CE - Biochemie

  • 2011 - 2014
    • •
  • 6 595 tis. Kč
    • •
  • 6 595 tis. Kč
    • •
  • GA ČR
Project

The role of lipids in the regulation of mitochondria-dependent cardioprotection. (ME09018)

In this project we propose to study primary unanswered questions which deal with the role of lipids in mitochondria-dependent cardioprotection. We will test approach include namely studies of K+ transport in intact heart mitochondria

ED - Fyziologie

  • 2009 - 2012
    • •
  • 2 400 tis. Kč
    • •
  • 2 400 tis. Kč
    • •
  • MŠMT
Project

Addiction to oxidative phosphorylation in cancer and its relation to tumour initiation and therapy (GA16-12816S)

Recent research indicates that cancer cells require functional mitochondria to initiate and form tumours in the mouse in vivo models. Cancer cells with dysfunctional mitochondria are able to „steal“ mitochondria by horizo...

FD - Onkologie a hematologie

  • 2016 - 2018
    • •
  • 8 417 tis. Kč
    • •
  • 8 363 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 238