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12 (0,102s) •

Project

ELISA kits for global diagnosis of viral neuroinfections (FR-TI3/106)

Neurological diseases represent one of the important problems in current healthcare. Environmental factors, stress and various infectious agents participate on the increase in their incidence during the last decade. Of virus pathogens the most known ...

EE - Mikrobiologie, virologie

  • 2011 - 2013
    • •
  • 6 122 tis. Kč
    • •
  • 3 500 tis. Kč
    • •
  • MPO
Project

Tick-borne neuroinfection - clinical manifestations and diagnostic (NT13467)

Lyme borreliosis is important zoonosis in Czech Republic. Its’ diagnostic is not optimal. Due to this fact the study was suggested with the aim to solve this problem. It is intended to corre-late EIA and WB tests for the detection of antibodies with ...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2012 - 2015
    • •
  • 6 665 tis. Kč
    • •
  • 6 665 tis. Kč
    • •
  • MZ
Project

Mechanisms of neuronal injury during tick-borne encephalitis virus infection of the CNS. (GA14-29256S)

Tick-borne encephalitis (TBE), a disease caused by tick-borne encephalitis virus (TBEV), represents one of the most important and serious neuroinfections in Europe and North-eastern Asia. Despite the medical importance of this disease, some ...

EE - Mikrobiologie, virologie

  • 2014 - 2016
    • •
  • 7 506 tis. Kč
    • •
  • 7 506 tis. Kč
    • •
  • GA ČR
Project

Development and testing of novel perspective antivirals and their prodrug forms active against tick-borne encephalitis virus (NV16-34238A)

Tick-borne encephalitis (TBE) represents one of the most important and serious viral neuroinfections in Europe and North-eastern Asia. Despite the medical importance of this disease, there is no specific treatment of TBE. In our laboratory, ...

EE - Mikrobiologie, virologie

  • 2016 - 2019
    • •
  • 8 950 tis. Kč
    • •
  • 8 950 tis. Kč
    • •
  • MZ
Project

Genetic predisposition to different clinical course and severity of tick-borne encephalitis (NV19-05-00457)

Tick-borne encephalitis (TBE) is the most important human viral neuroinfection in the Czech Republic. TBE severity can range from an asymptomatic or mild flu-like disease to meningitis or severe and potentially fatal meningoencephalitis or e...

Virology

  • 2019 - 2022
    • •
  • 13 687 tis. Kč
    • •
  • 13 687 tis. Kč
    • •
  • MZ
Project

Differential diagnostics of inflammatory and autoimmune CNS diseases by means of CSF protein fractions evaluation. (NF6460)

The project follows preceding works of our working group and assumes the evaluation of biological significance of CSF protein fractions by means of analytical methods, by monitoring CSF cytological picture and employment of the specificity of this be...

FH - Neurologie, neurochirurgie, neurovědy

  • 2001 - 2003
    • •
  • 1 069 tis. Kč
    • •
  • 990 tis. Kč
    • •
  • MZ
Project

New materials and technologies for development of multiplex test for complex diagnostics in medicine and food allergens detection (TA03010625)

for determination of IgG and IgM antibodies against main neuroinfections-associated pathogens, b...

EI - Biotechnologie a bionika

  • 2013 - 2015
    • •
  • 13 313 tis. Kč
    • •
  • 8 399 tis. Kč
    • •
  • TA ČR
Project

Autoantibodies as critical determinants of tick-borne encephalitis severity (NW25-05-00494)

Tick-borne encephalitis (TBE) is a serious neuroinfection caused by the tick-borne encephalitis virus (TBEV), prevalent in Europe and Northeast Asia, with over 13,000 clinical cases reported annually, including numerous deaths. Despite its m...

Virology

  • 2025 - 2028
    • •
  • 13 313 tis. Kč
    • •
  • 13 313 tis. Kč
    • •
  • MZ
Project

Spatial metabolomics in central nervous system infections (GA22-06771S)

Bacterial, fungal, and viral pathogens penetrating the nervous system of patients at risk (including neonates) trigger an immune cascade resulting in inflammation, leading to altered metabolic pathways and neuropathological changes in the brain. Bloo...

Analytical chemistry

  • 2022 - 2024
    • •
  • 10 100 tis. Kč
    • •
  • 10 100 tis. Kč
    • •
  • GA ČR
Project

Molecular pathogenesis of alimentary infection by tick-borne encephalitis virus. (GA23-07160S)

Tick-borne encephalitis (TBE) is one of the most serious neuroinfections in Europe and Northeast Asia. In most cases, people become infected with TBE virus (TBEV) during the feeding of an infected tick. However, there are also increasing num...

Virology

  • 2023 - 2025
    • •
  • 12 063 tis. Kč
    • •
  • 12 051 tis. Kč
    • •
  • GA ČR
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