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24 (0,286s) •

Project

Influence of Human Growth Hormone Treatment Together with Glutamine Supplementation on Immune and Metabolic Status of Critically Ill (NR8230)

The study is designed to evaluate the efficacy of the low-dose i.v. growth hormone treatment together with glutamine supplementation in the critically ill. We presume that glutamine supplementation is able to prevent growth hormone-...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2004 - 2007
    • •
  • 1 774 tis. Kč
    • •
  • 1 509 tis. Kč
    • •
  • MZ
Project

The difference between an influence of glutamine and glutamate in parenteral nutrition (NB6755)

In prospective ceoss-over randomised study the influence of two parenteral nutrition solutions (the first one with glutamine and the second one with equivalent amount of glutamate) on nitrogen balance, plasma proteins and plasma aminogram wi...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2001 - 2002
    • •
  • 1 282 tis. Kč
    • •
  • 972 tis. Kč
    • •
  • MZ
Project

Effect of growth hormone and glutamine on protein metabolism in isolated skeletal muscle. (NB7611)

Possibilities of influencing protein catabolism by treatment with growth hormone and glutamine will be studied using the method of incubation of isolated rat skeletal muscle. Major parameters of protein metabolism will be assessed using radi...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2003 - 2005
    • •
  • 934 tis. Kč
    • •
  • 931 tis. Kč
    • •
  • MZ
Project

Glutamine enriched parenteral nutrition and antioxidants in the treatment of the inflammatory bowel disease. (IZ2316)

9F - 9

  • 1994 - 1995
    • •
  • 378 tis. Kč
    • •
  • 756 tis. Kč
    • •
  • MZ
Project

METABOLIC CONSEQUENCES OF MASSIVE SMALL BOWEL RESECTION. (NR8043)

of amino acids, mainly glutamine and citrulline in patients with the short bowel in patients who are on a standard nutritional regime enriched in glutamine. Other be studied. The secondary objective is to study the influence of

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2004 - 2006
    • •
  • 1 770 tis. Kč
    • •
  • 1 577 tis. Kč
    • •
  • MZ
Project

Organ - specific nutrition in patients treated with high-dose chemotherapy and autologous stem-cell transplantation. (NB5502)

The effect of glutamine supplementation in patients with hifh-dose chemotherapy and stem-cell transplantation will be studied in a double-blind randomized prospective clinical trial. Gut permeability, lymphocyte recovery rate, nutritional st...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1999 - 2001
    • •
  • 2 113 tis. Kč
    • •
  • 2 113 tis. Kč
    • •
  • MZ
Project

Tumor targeted prodrugs of glutamine antagonists (LTAUSA18166)

Synthesis of prodrugs of glutamine antagonist 6-diazo-5-oxo-L-norleucine with specific ability to release the parent drug in target cancer cells by the action of enzymes overexpressed in cancer tissues. Pharmacokinetic studies of synthesized...

Organic chemistry

  • 2019 - 2022
    • •
  • 8 040 tis. Kč
    • •
  • 6 368 tis. Kč
    • •
  • MŠMT
Project

Butyrate and glutamine in the local rectal therapy of pouchitis radiation induced proctocolitis and rectal forms of inflammatory bowel diseases (ND6302)

The project deals with the local treatment of pouchitis, postradiation proctocolitis and rectal form of Crohn´s disease be means of rectal application of suppositories containing glutamine and butyrate. We suppose that this treatment improve...

FJ - Chirurgie včetně transplantologie

  • 2000 - 2002
    • •
  • 643 tis. Kč
    • •
  • 643 tis. Kč
    • •
  • MZ
Project

The role of mitochondrial IDH2 in bioenergetics, redox regulations, and cancer (GPP301/12/P381)

project is to elucidate a role of glutamine and glutaminolysis in mitochondrial bioenergetics, with focus on glutamine-dependent reductive carboxylation pathway to quantify the extent of reductive carboxylation and variations of

FD - Onkologie a hematologie

  • 2012 - 2014
    • •
  • 2 430 tis. Kč
    • •
  • 2 430 tis. Kč
    • •
  • GA ČR
Project

Glutamine-supplemented parenteral nutritional support in patients with peripheral stem cells transplantation for hematologic malignancies. (NB7000)

Our aim is to evaluate the signifance of prophylactic parenteral nutrition in stem cells transplantation for heatologic malignancies and possible advantage of blutamine-suplementation over standard formula.......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2002 - 2003
    • •
  • 686 tis. Kč
    • •
  • 646 tis. Kč
    • •
  • MZ
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