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2 486 (0,104s) •

Project

Function of nuclear myosin in gene expression (GA204/04/0108)

We have demonstrated previously the presence of myosin I beta in nucleus. We that the nuclear myosin and actin are required for transcription by RNA polymerases I and II, described that the myosin has a ca...

EA - Morfologické obory a cytologie

  • 2004 - 2006
    • •
  • 3 313 tis. Kč
    • •
  • 3 313 tis. Kč
    • •
  • GA ČR
Project

Charakterization of putative probably nuclear myosin I (ME 470)

The project aims to define functions of the newly discovered nuclear myosin in the cell nucleus. Methods of molecular biology and microscopy will be used including observing GFP-constracts in living cells.......

EB - Genetika a molekulární biologie

  • 2001 - 2003
    • •
  • 3 687 tis. Kč
    • •
  • 1 527 tis. Kč
    • •
  • MŠMT
Project

Function of nuclear myosin I (GA304/01/0661)

We have demonstrated previously the presence of a 120 kDa, myosin 1-like protein in the nucleus. Microsequencing and analysis of the cDNA have then revealed that the 120 kDa protein is a form of myosin Iß that contains a unique 16 a...

EA - Morfologické obory a cytologie

  • 2001 - 2003
    • •
  • 5 233 tis. Kč
    • •
  • 3 266 tis. Kč
    • •
  • GA ČR
Project

Characterization of a putative nuclear myosin I (ME 143)

A novel nuclear 120kDa protein has been characterized as myosin I isoform. It binds l25I-calmodulin and is photoaffinity-labeled with ATP. Column fractions containing the 120 kDa protein contain K+-EDTA ATPase activity. The partiall...

EA - Morfologické obory a cytologie

  • 1998 - 2000
    • •
  • 1 345 tis. Kč
    • •
  • 1 051 tis. Kč
    • •
  • MŠMT
Project

Cooperative contribution of actin- and myosin-families to the chromatin dynamics and tranion in the cell nucleus (LH12143)

Identification of principles of collaborative action of actin-related Arp6) and myosin (NM1) proteins in functional organization of the cell nucleus and chromatin. The project aims to asses especially their contribution to the organization o...

EB - Genetika a molekulární biologie

  • 2012 - 2014
    • •
  • 3 635 tis. Kč
    • •
  • 3 635 tis. Kč
    • •
  • MŠMT
Project

Functions of myosin I and its binding partners in the cell nucleus (GAP305/11/2232)

Previously, we identified 120 kDa nuclear protein as a unique myosin 1C form (NM1). After that, we have shown that NM1 and actin are required for transcription by RNA polymerases I and II, and described that NM1 binds to TIFIA trans...

EB - Genetika a molekulární biologie

  • 2011 - 2015
    • •
  • 16 996 tis. Kč
    • •
  • 16 996 tis. Kč
    • •
  • GA ČR
Project

Cooperative contribution of actin- and myosin-families to the chromatin dynamics and tranion in the cell nucleus (ME09101)

Identification of principles of collaborative action of actin-related (Arp6) and mypson (NM1) proteins in functional organization of the cell nucleus and chromatin. The project aims to asses especially their contribution to the organization of chromo...

EB - Genetika a molekulární biologie

  • 2009 - 2010
    • •
  • 1 336 tis. Kč
    • •
  • 1 336 tis. Kč
    • •
  • MŠMT
Project

Force coupling between microtubules and actin filaments mediated by unconventional myosins. (GA15-17488S)

, actin filaments and microtubules, such as unconventional myosin-I and -X, were shown to be necessary for proper spindle remodeling. However, how are the actin-myosin generated myosins and in vitro reconstituted m...

BO - Biofyzika

  • 2015 - 2017
    • •
  • 4 737 tis. Kč
    • •
  • 4 737 tis. Kč
    • •
  • GA ČR
Project

Functions of nuclear myosin in gene expression (GA204/07/1592)

In 1997, we identified 120 kDa nuclear protein as a unique myosin IC form (NMI). Recently, we have shown that NMI and actin are required for transcription by RNA polymerases I and II, and described that NMI binds to TIFIA transcript...

EB - Genetika a molekulární biologie

  • 2007 - 2009
    • •
  • 5 701 tis. Kč
    • •
  • 5 701 tis. Kč
    • •
  • GA ČR
Project

Familial hypertrophic cardiomyopathy detection of mutations in exon 13 of the beta-myosin heavy chain. (IZ2971)

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 1995 - 1997
    • •
  • 771 tis. Kč
    • •
  • 723 tis. Kč
    • •
  • MZ
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