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14 (0,085s)

Project

The influence of ascorbic acid on phenotyp in Charcot Marie Tooth disease type 1A (NR9517)

To evaluate an influence of ascorbic acid on phenotype of CMT1A neuropathy. The cohort of sixty patients will be treated ( AA vs placebo) fot two years. The primary efficacy outcome will be an improvement on CMTNS, electro- physiological par...

FH - Neurologie, neurochirurgie, neurovědy

  • 2007 - 2010
  • 4 183 tis. Kč
  • 3 986 tis. Kč
  • MZ
Project

Cytogenetic analysis of peripheral blood lymphocytes and effect of high-dose ascorbic acid prophylactics in workers occupationally exposed to halogenated ethete (IZ2459)

FM - Hygiena

  • 1994 - 1994
  • 0 tis. Kč
  • 0 tis. Kč
  • MZ
Project

Establishing the signaling pathway associated with secondary injury, reactive oxygen species and inflammation in spinal cord injury and during its repair. (LTAUSA17120)

nanoparticles with ascorbic acid on their surface....

FH - Neurologie, neurochirurgie, neurovědy

  • 2017 - 2020
  • 7 673 tis. Kč
  • 7 673 tis. Kč
  • MŠMT
Project

Antioxidants and antioxidative activity of selected minor crops species for improving of human nutrition (QH92111)

The aim of the project is evaluation of the selected genetic resources of minor crops (buckwheat, emmer wheat, einkorn wheat, amaranth) in relation to the content of antioxidants (polyphenols, phenolic acids, flavonoids, ascorbic acid, tocop...

GM - Potravinářství

  • 2009 - 2011
  • 3 406 tis. Kč
  • 3 033 tis. Kč
  • MZe
Project

Changes in the content and composition of antioxidants in high-light stressed lichens (GP206/06/P209)

The proposed project will contribute to the understanding of the relation of glutathione, ascorbate, tocopherol and zeaxanthin formation, changes in their pool and their dynamics in lichens in response to various irradiance (low, medium, hig...

EF - Botanika

  • 2006 - 2008
  • 977 tis. Kč
  • 977 tis. Kč
  • GA ČR
Project

Phenolic metabolism, antioxidants and stress tolerance in algae (GA14-28933S)

(ascorbate and glutathione) using specific inhibitors will be studied. Selected...

ED - Fyziologie

  • 2014 - 2018
  • 3 120 tis. Kč
  • 3 120 tis. Kč
  • GA ČR
Project

The antioxidative protection in chloroplasts and senescence initiation in tobacco plants (GP522/05/P558)

(superoxide dismutase, ascorbate peroxidase, monodehydroascorbate reductase, dehydroascorbate reductase, glutathione reductase, ascorbate, glutathione and carotenoids......

ED - Fyziologie

  • 2005 - 2007
  • 1 131 tis. Kč
  • 1 131 tis. Kč
  • GA ČR
Project

Development of new diagnostic methods for the monitoring of bioactive markers using new trends in separation and detection techniques - UPLC/MS/M (GP203/07/P370)

The aim of proposed project is the development of highly sensitive and selective analytical methods with the intention of use for diagnostic determination of biological markers ascorbic and dehydroascorbic acid and also neopterin and its der...

CB - Analytická chemie, separace

  • 2007 - 2009
  • 786 tis. Kč
  • 786 tis. Kč
  • GA ČR
Project

Supramolecular antioxidants protecting proteins against oxidative damage (LD13041)

New methods of dimerization applicable to the sensitive antioxidants employing chemoenzymatic methods will be developed. Homo- and heterodimers based on flavonolignans silybin, dehydrosilybin and its congeners in the combination with other bioactive ...

CE - Biochemie

  • 2013 - 2014
  • 941 tis. Kč
  • 941 tis. Kč
  • MŠMT
Project

Polyphenolic compounds in traditional agricultural crops (7AMB12SK018)

The project will assess the impact of growing conditions (soil, climate, precipitation factors) on changes in nutrients for monitored agricultural crops. It will be evaluated 1) the influence of the variety and growing conditions on the content of co...

GM - Potravinářství

  • 2012 - 2013
  • 92 tis. Kč
  • 92 tis. Kč
  • MŠMT
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