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Molecular-biological and histopathological characteristics of tumor infiltrating lymphocytes as instrument of prediction of risk of early colorectal cancer recurrence (NT12025)
to the behavior of tumor infiltrating lymphocyte tissue between patients with colorectal...
FJ - Chirurgie včetně transplantologie
- 2011 - 2014 •
- 5 261 tis. Kč •
- 5 261 tis. Kč •
- MZ
Řešení projektu: 1. 6. 2011 - 31. 12. 2014
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Predictive factors of pathologic response to neoadjuvant chemotherapy in patients with HER-2 positive or triple negative breast carcinoma (NT13564)
centers difference in tumor infiltrating lymphocytes in patients with different tumor and the presence of tumor infiltrating lymphocytes will be evaluated together with tumor re...
FD - Onkologie a hematologie
- 2012 - 2015 •
- 9 695 tis. Kč •
- 9 695 tis. Kč •
- MZ
Řešení projektu: 1. 4. 2012 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
The importance of infiltrating immunocompetent cells for the development of head and neck squamous cell carcinoma (NT11542)
Tumor infiltrating cells of the immune system, including tumor associated macrophages (TAM) and regulatory T lymphocytes (Treg) interact not only with tumor cells of interactions of tumor cells, i...
FF - ORL, oftalmologie, stomatologie
- 2010 - 2015 •
- 8 722 tis. Kč •
- 8 722 tis. Kč •
- MZ
Řešení projektu: 1. 9. 2010 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Correlation of immunotherapeutic molecular targets with gut microbiome in NSCLC patients (NV19-03-00069)
During the recent years, cancer immunotherapy has been rediscovered and in some cases of solid and haematological tumours also successfully implemented into the therapeutic strategy. Tumour infiltrating T lymphocytes exists in diffe...
Oncology
- 2019 - 2022 •
- 14 064 tis. Kč •
- 14 064 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2019 - 31. 12. 2022
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Determination of functional activities and phenotype of tumor infiltrating lymphocytes in patients with ovarian cancer (NH5196)
This is project destined to investigate the potential role of adoptive ommunotherapy in the treatment of ovarian cancer.Preclinical data on henotype and cytotoxic activity of TIL,and concentrations of markers of immune activation in malignit. In the ...
EC - Imunologie
- 1999 - 2001 •
- 944 tis. Kč •
- 944 tis. Kč •
- MZ
Řešení projektu: 1. 1. 1999 - 1. 1. 2001
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Antigen receptor rearrangement profiling in immune monitoring and treatment response prediction of malignant diseases (NU20-03-00284)
in infiltrating physiological lymphocytes. The methodology will unite and simplify the current of infiltrating immune cells (mainly T lymphocytes) and a potential for immunotherapy.......
Immunology
- 2020 - 2023 •
- 9 182 tis. Kč •
- 9 182 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2020 - 31. 12. 2023
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
The prognostic predictive markers in penile carcinoma a molecular and morphological study. (NU21J-03-00019)
infiltrating T-lymphocytes, expression of programmed death ligand 1 (PD-L1) with possible to a metastatic disease and death of affected persons, whereas there is only a localized tumor potential from less aggressive tu...
Pathology
- 2021 - 2024 •
- 6 978 tis. Kč •
- 6 978 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2021 - 31. 12. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Combined immunotherapy of tumors with different expression of MHC class I molecules (GA16-04477S)
the viral E7 oncoprotein. Tumor-infiltrating cells, especially macrophages, myeloid-derived suppressor cells, NK cells, NKT cells, and T and B lymphocytesThis study will focus on the immunotherapy of tumors with r...
EC - Imunologie
- 2016 - 2020 •
- 8 919 tis. Kč •
- 8 724 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2016 - 22. 7. 2020
Uznané náklady
Podpora ze státního rozpočtu (98%)
Poskytovatel: Grantová agentura České republiky
Complex morphological, immunohistochemical, molecular genetic and clinico-pathological analysis of rare types of ovarian carcinomas (NV19-03-00007)
Most (about 70%) malignant epithelial ovarian tumors are high grade serous%). However, these tumors, despite low incidence, pose a serious problem, especially regarding the therapeutic potential of advanced tumors. Currentl...
Pathology
- 2019 - 2022 •
- 19 091 tis. Kč •
- 19 091 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2019 - 31. 12. 2022
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Genetically downregulated expression of the immune checkpoint inhibitor LAIR-1 in tumor-specific T cells as a novel strategy for breaking the resistance of solid tumors to adoptive T cell (NU23-08-00071)
tumor-specific T cells from the tumor-infiltrating lymphocytes or peripheral blood in the treatment of solid tumors. The failure is often caused by an inability of T cells to infiltrate tumor...
Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)
- 2023 - 2026 •
- 11 244 tis. Kč •
- 11 244 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2023 - 31. 12. 2026
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
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