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288 (0,082s) •

Project

IBIS - Inteligent biosensor system for environmental detection of pesticides and herbicides. (FT-TA/089)

pesticides and photosyntetic herbicides. The factors which suppress the organophosphate with organophosphate pesticides and photosyntetic herbicides detecting biosensorsBasic research of correlations between outpu...

JB - Senzory, čidla, měření a regulace

  • 2004 - 2007
    • •
  • 14 915 tis. Kč
    • •
  • 11 880 tis. Kč
    • •
  • MPO
Project

*Construction of simple dipstickfor organophosphates assay (FR-TI1/541)

pesticide solutions and assaying of organophosphates and carbamates in simulated of cholinesterases. Organophosphates and carbamates will be assayed during project solution of organophosphates (carbamates) presenc...

CB - Analytická chemie, separace

  • 2009 - 2011
    • •
  • 10 576 tis. Kč
    • •
  • 6 599 tis. Kč
    • •
  • MPO
Project

Colorimetric sensor for diagnosis of pesticides poisoning (TH03030336)

The project is focused to construction of a colorimetric sensor for a fast diagnosis of pesticides poisoning and it will be suitable for the both human and veterinarian samples. Functional sample of the device will be verified on biological ...

Analytical chemistry

  • 2018 - 2021
    • •
  • 5 092 tis. Kč
    • •
  • 3 053 tis. Kč
    • •
  • TA ČR
Project

Development of novel antidotal treatment against organophosphorus pesticides (ME09086)

The development of the broad-spectrum acetylcholinesterase reactivator against organophosphorus pesticides (OPP) is the main aim of the whole project. The synthesis and in vitro evaluation of novel or formerly prepared compounds will be used...

FR - Farmakologie a lékárnická chemie

  • 2009 - 2012
    • •
  • 1 692 tis. Kč
    • •
  • 1 692 tis. Kč
    • •
  • MŠMT
Project

Preparation and biological evaluation of new therapeutics against to pesticides (NT12062)

The main aim of this project is to search for new and convenient therapeutics that will be more effective in therapy of pesticide poisoning (pesticides are commonly used organophosphate inhibitors of cholinesterases). New s...

FR - Farmakologie a lékárnická chemie

  • 2011 - 2014
    • •
  • 4 244 tis. Kč
    • •
  • 4 244 tis. Kč
    • •
  • MZ
Project

Centrally acting antidotes for the treatment of organophosphorus poisoning (NV17-32801A)

Inactivation of acetylcholinestarse (AChE) in nerve and muscle by organophosphates is the toxic mechanism common to both nerve agents and pesticides. Standard countermeasures against OP poisoning involves muscarinic inhibition and t...

FR - Farmakologie a lékárnická chemie

  • 2017 - 2020
    • •
  • 8 990 tis. Kč
    • •
  • 8 990 tis. Kč
    • •
  • MZ
Project

Development of Czech-Norwegian cooperation in the treatment of organophosphorus poisoning (7F16034)

Organophosphate (OP) and warfare nerve agent- and pesticide- poisoning is a persistent world - wide problem, the latter alone with hundreds of thousand casualties every year. Informal cooperation between the Czech researchers and FF...

FH - Neurologie, neurochirurgie, neurovědy

  • 2017 - 2017
    • •
  • 111 tis. Kč
    • •
  • 111 tis. Kč
    • •
  • MŠMT
Project

Novel prophylactic antidotes of nerve agent poisonings based on scavengers (OVUOFVZ200902)

Organophosphorus compounds are weaponized in some countries as chemical warfare agents (sarin, tabun, VX). These compounds inhibit enzymes acetylcholinesterase and butyrylcholinesterase. As antidotes of poisonings by these compounds are often used an...

FP - Ostatní lékařské obory

  • 2009 - 2012
    • •
  • 1 792 tis. Kč
    • •
  • 864 tis. Kč
    • •
  • MO
Project

Development of the effective drug delivery system intended for application in organophosphate poisoning for intranasal administration (FW09020121)

The aim of the project is to develop, evaluate and to transfer into prototype production an original drug used for noninvasive application of active substances in therapy of organophosphate poisoning. Specific aims are: • to design and devel...

Pharmacology and pharmacy

  • 2023 - 2027
    • •
  • 11 780 tis. Kč
    • •
  • 7 643 tis. Kč
    • •
  • TA ČR
Project

Encapsulation of bisquaternary oxime reactivators into solid lipid nanoparticles for enhanced reactivation of cholinesterases in CNS (GA25-15339S)

Quaternary oxime reactivators of cholinesterases are used for life endangering intoxications by organophosphates. They are effective in the peripheral tissues the organophosphates cause irreversible damage of the neuronal tissues, i...

Neurosciences (including psychophysiology)

  • 2025 - 2027
    • •
  • 13 027 tis. Kč
    • •
  • 13 027 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 288