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3 459 (0,174s) •

Project

High throughput bacterial genome assembly and annotation techniques using genomic signal processing (GA17-01821S)

The project is focused on computational whole-genome analysis of bacteria using digital signal processing methods (DSP). As first, a new algorithm for genome assembly in signal representation. The algorithm will be...

IN - Informatika

  • 2017 - 2021
    • •
  • 5 555 tis. Kč
    • •
  • 5 483 tis. Kč
    • •
  • GA ČR
Project

Retrotransposon colonizing only recombining part of genome of dioecious plants (GPP501/10/P483)

Large portions of eukaryotic genomes consist of transposable elements (TEs). Chromosomal distribution and abundance of various families of TEs in genomes is affected of the repetitive sequences in S. latifolia genome, gypsy...

EB - Genetika a molekulární biologie

  • 2010 - 2014
    • •
  • 1 897 tis. Kč
    • •
  • 1 897 tis. Kč
    • •
  • GA ČR
Project

Hemicatenated DNA loops their occurence in humen genome and recognition by tumor suppressor protein p53 (IAA400040702)

Results of mapping of human genome provided evidence that DNA sequences encoding proteins represented only ~3% of human genome. Alternative DNA structures are of particular interest as potential signals to mark important si...

CE - Biochemie

  • 2007 - 2010
    • •
  • 2 428 tis. Kč
    • •
  • 2 428 tis. Kč
    • •
  • AV ČR
Project

Signaling pathways regulating genome integrity during oocyte-to-embryo transition (GA25-18241S)

development jeopardizes genomic stability. The formation of aneuploid embryos diminishes microscopy, RNA sequencing, and proteomics to explore the role of signaling pathways phase required to accumulate zygotic genome acti...

Cell biology

  • 2025 - 2027
    • •
  • 8 121 tis. Kč
    • •
  • 8 121 tis. Kč
    • •
  • GA ČR
Project

Identification of cis-acting signal and trans-acting proteins involved in DNA encapsidation and viral assembly of mouse polyomavirus. (GPP302/10/P118)

of this proposal is to identify cis-acting DNA signal sequence for encapsidation of viral genome as well as trans-acting protein/s involved in virion assembly experimental methods for verification of requirement of these elements i...

EE - Mikrobiologie, virologie

  • 2010 - 2014
    • •
  • 2 298 tis. Kč
    • •
  • 2 298 tis. Kč
    • •
  • GA ČR
Project

Selection of genomic defects in chronic lymphocytic leukemia and their impact on disease outcome (NV15-31834A)

In chronic lymphocytic leukemia (CLL), the absence of primary genomic defect of complex genomic changes since they typically represent cases with more aggressive to uncover genetic defects contributing to the development of geno...

FD - Onkologie a hematologie

  • 2015 - 2018
    • •
  • 9 912 tis. Kč
    • •
  • 9 912 tis. Kč
    • •
  • MZ
Project

Signal integration and epigenetic reprograming for plant productivity (EF16_026/0008446)

) Determining novel interactions among key signalling pathways and describing their importance in abiotic interactions. (ii) Describing the key signalling/regulatory with the image-derived information. (v) Targeted genome m...

GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming

  • 2018 - 2023
    • •
  • 99 723 tis. Kč
    • •
  • 99 723 tis. Kč
    • •
  • MŠMT
Project

Cell death pathways in mesothelioma cells exposed to pharmacological and immunological inducers of apoptosis genomic and proteomic approach (IAA500520602)

will be treated and probed for activation of signalling pathways using genomic and proteomic models. The precise mechanisms, by which a-TOS induces apoptotic signaling......

FD - Onkologie a hematologie

  • 2006 - 2008
    • •
  • 3 196 tis. Kč
    • •
  • 3 196 tis. Kč
    • •
  • AV ČR
Project

Genomic integrity and instability mechanisms in the pathogenesis and potential personalized targeted treatment of prostate cancer. (NS10282)

Genomic integrity and instability mechanisms in the pathogenesis and potential personalized targeted treatment of prostate cancer. PI: J. Bártek The key topic of this project is analysis of cell cycle checkpoints and genome integrit...

FD - Onkologie a hematologie

  • 2009 - 2011
    • •
  • 5 158 tis. Kč
    • •
  • 5 148 tis. Kč
    • •
  • MZ
Project

Integrated genomic analysis of chronic lymphocytic leukemia (CLL) for genetic and clinical identification of subgroups with aberrations of selected chromosomes. (NT13576)

To use chip technologies and molecular genetic methods in the study of gene changes in the tumor genome of patients with CLL to determine genetic changes to analyze the genome of CLL patients at diagnosis and in the course of the di...

FE - Ostatní obory vnitřního lékařství

  • 2012 - 2015
    • •
  • 9 477 tis. Kč
    • •
  • 9 477 tis. Kč
    • •
  • MZ
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