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2 528 (0,172s) •

Project

Novel Tools for Cell Cycle Analysis (TA03010719)

The determination of the cell proliferation activity is a basic methodological approach for the evaluation of the cell population conditions in many situations e.g. in the evaluation of the genotoxicity or in the analysis of the effect of agents with...

EI - Biotechnologie a bionika

  • 2013 - 2015
    • •
  • 9 600 tis. Kč
    • •
  • 6 000 tis. Kč
    • •
  • TA ČR
Project

Technology of recycling of waste raw materials produced during powder metallurgy of special metal materials (FR-TI1/221)

sintering including recycling of material removed by machining, the second one is recycling of turnings by oxidation/reduction process (turnings disintegrate......

JG - Hutnictví, kovové materiály

  • 2009 - 2013
    • •
  • 35 922 tis. Kč
    • •
  • 22 400 tis. Kč
    • •
  • MPO
Project

Structure and Properties of Modified Components of Nucleic Acids (GA13-24880S)

, nucleosides and nucleotides, by means of experimental NMR (high-resolution liquid NMR and solid-state NMR), calculation of the NMR parameters (nuclear shielding constants......

CB - Analytická chemie, separace

  • 2013 - 2015
    • •
  • 6 006 tis. Kč
    • •
  • 6 006 tis. Kč
    • •
  • GA ČR
Project

New derivatives of 5-azacytosine nucleosides like demethylating therapeutics identification of clinical candidates and efficiency biomarkers. (FR-TI4/625)

The project is focused to the development of new hypomethylating agents based on polymer conjugates of 5-azacytosine nucleosides and their 5,6-dihydro congeners, which will increase plasma half-life of the drug. This will not only pronounce ...

FD - Onkologie a hematologie

  • 2012 - 2015
    • •
  • 31 955 tis. Kč
    • •
  • 25 152 tis. Kč
    • •
  • MPO
Project

Radiolytic damage of DNA bases (KJB4048401)

Oxidative damage of DNA bases belongs to the most severe DNA damages caused, nucleosides and short DNA oligomers. The diffusion of radicals produced by water. Probabilities of reactions with particular sites within nucleobases, ...

CE - Biochemie

  • 2004 - 2005
    • •
  • 278 tis. Kč
    • •
  • 278 tis. Kč
    • •
  • AV ČR
Project

Use of Biomembrane technology for biochemical removal of H2S from biogas (TA03021413)

research is focused only on biological oxidative process for removal nitrogen or carbon sulfide removal from biogas which uses direct addition of air into gas or liquid phase oxidizing bacteria which oxidize

CE - Biochemie

  • 2013 - 2015
    • •
  • 8 288 tis. Kč
    • •
  • 5 226 tis. Kč
    • •
  • TA ČR
Project

Development of technology for removal of organic substances with a focus on substances known in coking technology as "tarry substance" from coking plant sewage. (TA04021212)

The aim of the project is to develop technologies suitable for the removal of organic substances from coke wastewater produced in the process of high-temperature carbonization of coal. Three types of methods will be examined: - oxidatio...

CI - Průmyslová chemie a chemické inženýrství

  • 2014 - 2017
    • •
  • 9 264 tis. Kč
    • •
  • 5 975 tis. Kč
    • •
  • TA ČR
Project

Development of modular syntheses of new C-nucleosides for studying DNA polymerase specificity and for the extension of the genetic alphabet (IAA400550902)

Novel modular methodologies for synthesis of new C-nucleosides will be developed based on cross-coupling reactions of haloaryl C-nucleosides of new C-nucleosides for biological activity screening and for applications chemic...

CC - Organická chemie

  • 2009 - 2012
    • •
  • 5 860 tis. Kč
    • •
  • 5 860 tis. Kč
    • •
  • AV ČR
Project

Immunomodulatory activity of adenosine receptor systém and its role in immunobiological effects of antiviral acyclic nucleoside phosphonates (GA305/03/1470)

andimmune-activated expression of cytokines, mainly chemokines, and nitric oxide will be antiviral acyclic nucleoside phosphonates (ANPs). Special attention will be paid to anti......

FR - Farmakologie a lékárnická chemie

  • 2003 - 2005
    • •
  • 3 395 tis. Kč
    • •
  • 3 395 tis. Kč
    • •
  • GA ČR
Project

New purine nucleoside analogues for therapeutic applications (OC D13.20)

Synthesis of purine nucleosides, heir acyclic analogues and analogues of nucleotides substituted by C=alkyl, aryl and cycloalkyl substituents as purinoceptor modulators.......

CC - Organická chemie

  • 2001 - 2003
    • •
  • 2 662 tis. Kč
    • •
  • 1 335 tis. Kč
    • •
  • MŠMT
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