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90 (0,257s) •

Project

Neural differentiation in microRNA induced pluripotent stem cells (NS10231)

This project concerns reprogramming somatic cells into pluripotent cells by micro RNA induction. Three cell lines will be transfected with miRNA. The success in reprogramming will be validated by reporter gene driven by pluripotent ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2009 - 2011
    • •
  • 3 094 tis. Kč
    • •
  • 3 094 tis. Kč
    • •
  • MZ
Project

Chicken pluripotent cells as a tool for construction of transgenic poultry (Gallus domesticus) (1P05ME722)

development of functional and practical methods of transgenic poultry construction with specific genetic information, establishment of specific cell line pluripotent cells......

GI - Šlechtění a plemenářství hospodářských zvířat

  • 2005 - 2008
    • •
  • 1 987 tis. Kč
    • •
  • 1 041 tis. Kč
    • •
  • MŠMT
Project

Chicken pluripotent cells as a source for production of transgenic domestic poultry (ME 460)

The object of the study is to develope functional model of isolation, cultivation , transfection and following insertion of chicken pluripotent cells. In this model Chinese and Czech lines of chicken breeds will be used.......

EI - Biotechnologie a bionika

  • 2001 - 2004
    • •
  • 2 870 tis. Kč
    • •
  • 1 370 tis. Kč
    • •
  • MŠMT
Project

Chicken pluripotent cells as source for production of transgenic poultry (ME 288)

The object of this project is to isolate Czech and Chinese chicken pluripotent cells (blastodermal,primordial gonocytes) for production of transgenic birds. These cells will be either immediately, or after incubation transfected with genetic...

GI - Šlechtění a plemenářství hospodářských zvířat

  • 1998 - 2000
    • •
  • 1 980 tis. Kč
    • •
  • 960 tis. Kč
    • •
  • MŠMT
Project

The role of transcription factors Tcf in the induced cell pluripotency (iPS) and during neurogenesis (GAP305/12/2042)

Induced pluripotent stem (iPS) cells share characteristics with embryonic stem into pluripotent cells including a gene delivery of the specific set of transcription factors Oct4, Sox2, c-myc and Klf4. Although these factors are esse...

EB - Genetika a molekulární biologie

  • 2012 - 2016
    • •
  • 8 747 tis. Kč
    • •
  • 8 747 tis. Kč
    • •
  • GA ČR
Project

Centre for pluripotent cells and genome instability research (EE2.3.20.0011)

The aim of the project is interdisciplinary extension, stabilization of research capacity and the introduction of new management system, evaluation and ethical principles into existing platforms biology of human pluripotent stem cells (KB) a...

EB - Genetika a molekulární biologie

  • 2011 - 2014
    • •
  • 35 645 tis. Kč
    • •
  • 35 645 tis. Kč
    • •
  • MŠMT
Project

Fam208a-associated epigenetic silencing and the maintenance of embryonic stem cell pluripotency (GA17-16959S)

is essential for the self-renewal of pluripotent stem cells. Using genetically modified and maintenance of the pluripotent state. Our research will contribute to the fundamental body......

EB - Genetika a molekulární biologie

  • 2017 - 2021
    • •
  • 9 171 tis. Kč
    • •
  • 8 115 tis. Kč
    • •
  • GA ČR
Project

A new options in cardiomyogenic differentiation of pluripotent stem cells (GA18-18235S)

demand and effort for an alternate cardiomyocyte source. Pluripotent stem cells, especially induced pluripotent stem cell (iPSC) are relatively available source......

Cell biology

  • 2018 - 2022
    • •
  • 4 547 tis. Kč
    • •
  • 4 424 tis. Kč
    • •
  • GA ČR
Project

Pluripotent cells as a sources of karyoplast in embryo cloning. (EP0960006200)

The object of our study is to analyse, by nuclear transplantation, changes in the pluripotent cells fused to enucleated oocytes and thereafter the developmental potential of karyoplast - cytoplast fusion products. The pluripotent ce...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 1996 - 2000
    • •
  • 1 873 tis. Kč
    • •
  • 1 873 tis. Kč
    • •
  • MZe
Project

The role of post-transtranional mechanisms in reprogramming of mouse oocytes into pluripotent cells (ME09039)

The goal of the project is to understand mechanisms involved in reprogramming gene expression during oocyte-to-zygote transition. It will bring new insights into dediferentiation and establishment of pluripotency, which are very important ar...

EB - Genetika a molekulární biologie

  • 2009 - 2012
    • •
  • 2 000 tis. Kč
    • •
  • 2 000 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 90