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329 (0,085s)

Project

Effect of growth hormone and glutamine on protein metabolism in isolated skeletal muscle. (NB7611)

Possibilities of influencing protein catabolism by treatment with growth hormone and glutamine will be studied using the method of incubation of isolated rat skeletal muscle. Major parameters of protein metabolism will be assessed u...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2003 - 2005
  • 934 tis. Kč
  • 931 tis. Kč
  • MZ
Project

Skeletal muscle metabolic abnormalities in patients with idiopathic inflammatory myopathies (NV16-33746A)

skeletal muscle, apparently as a consequence of inflammatory processes. In some patients, the muscle weakness remains even after pharmacological suppression function and metabolism of skeletal muscle modu...

FE - Ostatní obory vnitřního lékařství

  • 2016 - 2019
  • 9 387 tis. Kč
  • 9 387 tis. Kč
  • MZ
Project

Skeletal muscle regeneration in survivors of critical illness How to prevent satellite cell failure? (NU21J-06-00078)

failed functional outcomes associated with prolonged muscle weakness and fatiguability. Whilst alterations of skeletal muscle biology that occur during critical of satellite skeletal muscle cells, which a...

Critical care medicine and Emergency medicine

  • 2021 - 2025
  • 6 345 tis. Kč
  • 5 780 tis. Kč
  • MZ
Project

Muscle remodelling on the basis of extracellular matrix seeded with functionally characterized cells. (GA15-09161S)

the skeletal muscle with muscle-derived cells. Simultaneously, the physiopathological and evaluation of function of reconstructed muscles. This would be a novel approach for skeletal muscle recon...

ED - Fyziologie

  • 2015 - 2019
  • 5 955 tis. Kč
  • 5 955 tis. Kč
  • GA ČR
Project

Transduction systems coupled with the stimulation of the energy metabolism of mammalian skeletal muscle by the increased perfusion flow rate (GA305/02/1565)

skeletal muscle even under relaxed conditions. This phenomenon that was demonstrated on the model of the isolated in vitro perfused rat skeletal muscle as well, has systems are involved in the transduction of this...

ED - Fyziologie

  • 2002 - 2004
  • 2 016 tis. Kč
  • 936 tis. Kč
  • GA ČR
Project

The role of distal nerve stump on remodelling of capillary network and myosin heavy chain isoform transformation in denervated rat skeletal muscle. (MEB090910)

To measure the influence of distal nerve stump on expression of denervation changes in fast (extensor digitorum - EDL) and slow (soleus - SOL) rat skeletal muscle (changes in capillary bed and myosin heavy chain transformation).......

FH - Neurologie, neurochirurgie, neurovědy

  • 2009 - 2010
  • 122 tis. Kč
  • 122 tis. Kč
  • MŠMT
Project

Non-canonical role of ameloblastin in regulation of homeostasis in structural tissues and its potential clinical application (GJ19-19025Y)

identified strong phenotype in bone mineralization, skeletal muscle integrity and heart muscle function in Ambn KO mice. The aim of current proposal is characterisation of Ambn function in bone and muscle tissues,...

Cell biology

  • 2019 - 2023
  • 7 874 tis. Kč
  • 7 874 tis. Kč
  • GA ČR
Project

Analysis of expression and polymorphism of candidate genes regulating muscle development and growth in pigs (GA523/06/1302)

have initiated studies of differentially expressed genes in fetal skeletal muscles, with the goal to find genes and mutations playing role in muscle development. Analysis of these and other genes, as well as those expresse...

GI - Šlechtění a plemenářství hospodářských zvířat

  • 2006 - 2008
  • 3 350 tis. Kč
  • 3 350 tis. Kč
  • GA ČR
Project

Study of factors in a tissue microenvironment that influence the process of skeletal muscle reparation. (GA304/08/0329)

Degeneration of the cardiotoxin-damaged skeletal muscle is followed induction of a muscle damage, which impairs a natural course of myofibre regeneration muscle will be modified by local administration of cytokines...

EA - Morfologické obory a cytologie

  • 2008 - 2010
  • 4 020 tis. Kč
  • 4 020 tis. Kč
  • GA ČR
Project

Continuous biochemical monitoring of patients during open-heart surgery with cardiopulmonary bypass and during postoperative care using interstitial microdialysis. (NB6547)

) by comparison of changes in interstitial blood flow and metabolism of skeletal muscle duringContinuous monitoring of interstitial blood flow and metabolism of skeletal muscle by interstitial microdialysis in pati...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2001 - 2003
  • 1 581 tis. Kč
  • 1 567 tis. Kč
  • MZ
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