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6 033 (0,175s) •

Project

Targeting ovarian tumors to experimental drugs by inhibition of CDK12 kinase activity (NV16-34152A)

to the current or experimental therapies in ovarian tumors as well. The project focusesOvarian tumors represent about 16 % of all malignancies found in females in the Czech Republic. Despite tremendous advances in therapy,...

FD - Onkologie a hematologie

  • 2016 - 2019
    • •
  • 9 288 tis. Kč
    • •
  • 9 288 tis. Kč
    • •
  • MZ
Project

Specific metastatic site prediction due to the expression of "homing" factors in circulating tumor cells in experimental metastatic models (ME10045)

Project is going to characterize gene expression profiling of circulating tumor cells (CTC) in experimental mice metastatic models, with a special impact on gene expression of CTC homing factors. CTC are disseminated cells produced ...

EB - Genetika a molekulární biologie

  • 2010 - 2012
    • •
  • 3 063 tis. Kč
    • •
  • 3 063 tis. Kč
    • •
  • MŠMT
Project

Humanized patient-derived murine xenografts for experimental therapy of hematologic malignancies and for the study of in vivo acquired drug-resistance (NV19-08-00144)

Hematologic malignancies represent 5th most common type of tumor in the Czech tumor cells into immunodeficient mice became standard tools for confirmation of experimental treatment approaches. It is expected that experi...

Hematology

  • 2019 - 2022
    • •
  • 16 966 tis. Kč
    • •
  • 16 966 tis. Kč
    • •
  • MZ
Project

Experimental photodynamic therapy of tumore with employment of liposomal forms of novel photosenzitizers (NC6564)

Development and testing of liposomal forms of various photosenzitizers, eg.meso-tetrakis/phenylporphine (TPP), in order to obtain the highly efficient form for photodynamic therapy of tumors. The basic test will lie in the experimental

FD - Onkologie a hematologie

  • 2001 - 2003
    • •
  • 4 389 tis. Kč
    • •
  • 2 021 tis. Kč
    • •
  • MZ
Project

Complex liposomal forms of photosentitizers for experimental photodynamic therapy of tumors (NR7778)

We propose to develop and test, by experimental photodynamic therapy (PDT) of human tumors, the liposomal gel forms containing various hydrophobic, in order to reach approval for clinical testing. Depth profile of healing tumors...

FD - Onkologie a hematologie

  • 2004 - 2009
    • •
  • 8 383 tis. Kč
    • •
  • 4 651 tis. Kč
    • •
  • MZ
Project

Tumor stress-induced proteins as target structures for cytotoxic cells (IAA5020403)

against experimentally induced tumors IN VIVO.During the recent period, a number of new findings has been obtained about an alternative pathway for activation of cytotoxic cells that is dependent on the recognition of stress-induce...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2004 - 2008
    • •
  • 4 917 tis. Kč
    • •
  • 4 917 tis. Kč
    • •
  • AV ČR
Project

MBTA - adoptive immunotherapy of tumors (FW12010389)

The goal of the project is, through industrial research and experimental in the correct laboratory quality (SLK) for the treatment of malignant tumors, which will work on the principle of MBTA - non-cellular tumor immunothe...

Oncology

  • 2025 - 2027
    • •
  • 24 756 tis. Kč
    • •
  • 17 305 tis. Kč
    • •
  • TA ČR
Project

Experimental cancer immunotherapy, tumor heterogeneity, and overcoming tumor immune escape (GA19-00816S)

mechanisms that enable tumor cells to evade anti-tumor immune reactions. To stimulate anti-tumor immunity, adaptive immunity will be induced by DNA immunization and innate immunity, particularly repolarization of tumor...

Immunology

  • 2019 - 2022
    • •
  • 8 243 tis. Kč
    • •
  • 8 243 tis. Kč
    • •
  • GA ČR
Project

Glycomic and proteomic analysis of the molecular mechanisms of elimination of clinically relevant tumors by killer cells of the immune system (GA303/09/0477)

for the construction of compounds active in experimental tumor therapies. the recognition and elimination of tumor cells by the killer cells of the immune system. Moreover, the relation of tumor surface glycosylat...

CE - Biochemie

  • 2009 - 2013
    • •
  • 4 259 tis. Kč
    • •
  • 4 259 tis. Kč
    • •
  • GA ČR
Project

Experimental cancer of the liver tumor markers and therapeutic possibilities using cytostatic conjugates. (IZ2227)

9F - 9

  • 1994 - 1996
    • •
  • 2 153 tis. Kč
    • •
  • 3 156 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 6 033