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Epigenetic toolbox to control plant telomere maintenance (GA16-04653S)
Telomeres, nucleoprotein structures at the ends of eukaryotic chromosomes properties of telomeric chromatin were analysed using mammalian models telomeric repeats controversial data were obtained. In this project, we propos...
EB - Genetika a molekulární biologie
- 2016 - 2018 •
- 5 339 tis. Kč •
- 5 144 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2016 - 31. 12. 2018
Uznané náklady
Podpora ze státního rozpočtu (96%)
Poskytovatel: Grantová agentura České republiky
Topographic and functional characterization of telomeres in various tumor cell lines determined in situ and in vivo (GP204/05/P090)
so far, can be characterized by mechanisms maintaining viable length of telomeres. The ribonucleoprotein enzyme, known as telomerase, elongates telomeres in most tumors (85 to 90-negative tumors, which are provided with alternative...
EB - Genetika a molekulární biologie
- 2005 - 2007 •
- 1 175 tis. Kč •
- 1 175 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2005 - 31. 12. 2007
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Molecular evolution and functional analysis of components of plant telomeres and telomerases (GA521/05/0055)
Telomeres are nucleoprotein structures protecting chromosome ends from degradation and fusions. Many organisms use telomerase, comprising telomere reverse with the evolution of novel types of telomeres. In addition to group...
EB - Genetika a molekulární biologie
- 2005 - 2007 •
- 3 792 tis. Kč •
- 3 792 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2005 - 31. 12. 2007
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Telomeric chromatin in plants influenced by epigenetic drugs (LTC17077)
We propose to analyse telomeric chromatin in plant Cestrum elegans with non-canonical telomeric sequence TTTTTTAGGG. Modifications of telomeric histones of epigenetically active drugs. Moreover, the analysis of the telo...
EB - Genetika a molekulární biologie
- 2017 - 2019 •
- 1 470 tis. Kč •
- 1 470 tis. Kč •
- MŠMT
Řešení projektu: 1. 6. 2017 - 28. 2. 2019
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
Molecular nature of evolutionary telomere transitions in Asparagales plants (GA17-09644S)
In 2016, we identified unusual telomeres in Allium plants. Together with our earliear results, it is clear now that two telomere switches occurred in evolution plant telomeres (TTTAGGG)n were replaced with vertebrate-type (...
EB - Genetika a molekulární biologie
- 2017 - 2019 •
- 10 203 tis. Kč •
- 9 000 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2017 - 31. 12. 2019
Uznané náklady
Podpora ze státního rozpočtu (88%)
Poskytovatel: Grantová agentura České republiky
The estimation of telomeres length in different human tissues in the relation to the aging (GA303/08/1569)
Telomeres are structures capping the ends of eukaryotic chromosomes. They have limit length, the cells can divide no more. Shortening of telomeres was proved, the relationship between telomeres length and age of different t...
CE - Biochemie
- 2008 - 2009 •
- 818 tis. Kč •
- 818 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2008 - 31. 12. 2009
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Analysis of telomere length as a potential predictive factor of successful heart transplant. (NT14023)
, morphological and cellular changes. Independent of the age the telomeres may be engaged knowledge we supposed that the length of telomeres both in peripheral blood of telomeres will be connected with the duration of survi...
EB - Genetika a molekulární biologie
- 2013 - 2015 •
- 2 564 tis. Kč •
- 2 564 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2013 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Analysis of the structure of plant chromosome termini (GA521/96/1123)
in the project GA ČR 204/93/0053, those showing linkage to telomeres will be selected using pulsed field electrophoresis and in situ hybridisation. Other telomere associated sequences will be prepared using vectorette PCR on te...
CE - Biochemie
- 1996 - 1998 •
- 3 563 tis. Kč •
- 2 846 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 1996 - 1. 1. 1998
Uznané náklady
Podpora ze státního rozpočtu (80%)
Poskytovatel: Grantová agentura České republiky
Alternative telomeres with uknown sequence in plants (GP13-10948P)
Telomeres are physical ends of eukaryotic chromosomes that (i) compensate are conditioned by the presence of telomere proteins interacting in a complex called shelterin. Telomerase - reverse transcriptase - plays major role in t...
EB - Genetika a molekulární biologie
- 2013 - 2015 •
- 2 756 tis. Kč •
- 2 756 tis. Kč •
- GA ČR
Řešení projektu: 1. 2. 2013 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
The Dynamic World of Telomeres Unraveling Evolutionary Innovations in Genome Stability (GA25-15566S)
The project investigates the diversity and evolution of telomere maintenance and experimental methods, we will identify organisms using diverse types of telomeres and their phylogenetic distribution. We will identify new components ...
Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
- 2025 - 2028 •
- 12 829 tis. Kč •
- 12 829 tis. Kč •
- GA ČR
Řešení projektu: 1. 3. 2025 - 31. 12. 2028
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
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