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1 252 (0,103s) •

Project

Fluorescent techniques for the assassment of membrane potential in living cells (GA202/97/1121)

in living cells, which will be based on the use of fluorescent probes in combination biophysical techniques in both the selective detection of fluorescence emitted by probe respective fluorescence signals...

BG - Jaderná, atomová a molekulová fyzika, urychlovače

  • 1997 - 1999
    • •
  • 2 883 tis. Kč
    • •
  • 2 268 tis. Kč
    • •
  • GA ČR
Project

Molecular Fluorescent Probes for Selective Detection of Adenosine‐5’‐Triphosphate (ATP) (8J19UA048)

Elaboration of molecular fluorescent probes and test systems on their basis for selective detection of adenosine-5’-triphosphate (ATP) in aqueous solutions, and their following applications in pharmacology (as a method of preclinica...

Organic chemistry

  • 2019 - 2020
    • •
  • 92 tis. Kč
    • •
  • 92 tis. Kč
    • •
  • MŠMT
Project

Measurement of pH in model systems of liposomes by means of fluorescent probes using steady-state and time-resolved fluorescence techniques (GA202/99/0186)

in liposomes by means of fluorescent probes, including their application to the study fluorescence studies in both pure and protein-loaded liposomes stained by selected fluorescent dyes will provide better insight...

BG - Jaderná, atomová a molekulová fyzika, urychlovače

  • 1999 - 2001
    • •
  • 2 262 tis. Kč
    • •
  • 1 982 tis. Kč
    • •
  • GA ČR
Project

Development of Fluorescent Probes for Methionine Sulfoxide Reductase and Beyond (GJ17-25897Y)

The aim of this project is to develop a fluorescent probe for methionine sulfoxide reductase. Methionine sulfoxide reductase plays a pivotal role in cellular redox signaling and its importance have been implicated in a number of dis...

CC - Organická chemie

  • 2017 - 2019
    • •
  • 4 452 tis. Kč
    • •
  • 4 452 tis. Kč
    • •
  • GA ČR
Project

Bimetallic and trimetallic fluorescent nanoclusters synthesis, physico-chemical properties, and application in bio-imaging (GA19-03207S)

This project deals with metal nanoclusters possessing fluorescent properties. By a convenient combination of two and/or three metals, fluorescent as well as magnetic properties of particular components can be exploited; a (multi)bim...

Nano-materials (production and properties)

  • 2019 - 2022
    • •
  • 7 418 tis. Kč
    • •
  • 7 418 tis. Kč
    • •
  • GA ČR
Project

Development of fluorescent probes for determination of content, localization and trafficking of cholesterol within eukaryotic cells (GA17-02836S)

to prepare a new generation of fluorescent probes based on specific features of the molecular recognition of cholesterol. New filipin derivatives and novel fluorescent alfa advanced microscopic techniques. Based on the obt...

CB - Analytická chemie, separace

  • 2017 - 2021
    • •
  • 6 684 tis. Kč
    • •
  • 6 015 tis. Kč
    • •
  • GA ČR
Project

Design and Development of Visible Light-Activatable Groups and Fluorescent Probes for Chemistry and Biology (GA13-25775S)

The project seeks to explore and expand the field of photoactivatable (caged) compounds and fluorescent probes, the structures of which are based on similar features as fluorescent probes; small molecule fluorophor...

CC - Organická chemie

  • 2013 - 2017
    • •
  • 14 281 tis. Kč
    • •
  • 14 281 tis. Kč
    • •
  • GA ČR
Project

Functional Characterization of Bacterial Proton-Dependent Manganese Transporters (MntH) using Fluorescence Methods (1K04019)

ratiometric Green Fluorescent Protein and a metal sensitive fluorescent probe, respectively. These fluorescence assays will be used to investigate the potential binding sites in bacterial MntH transporters, to

BO - Biofyzika

  • 2004 - 2006
    • •
  • 3 106 tis. Kč
    • •
  • 2 682 tis. Kč
    • •
  • MŠMT
Project

*Inovation of real-time PCR probes (FR-TI1/112)

*This project is aimed on innovation of probes for real-time PCR - a molecular, allelic discrimination and pathogen detection. Hydrolysation dual-labeled fluorescent probes are the most frequent type of probes. In ...

EB - Genetika a molekulární biologie

  • 2009 - 2012
    • •
  • 15 712 tis. Kč
    • •
  • 12 553 tis. Kč
    • •
  • MPO
Project

Multi-FRET fluorescent probes responding to hydrolases (GA19-23972S)

The project is focused on synthesis of model systems for detection of two or three proteases solely or in their mixture via fluorescence multi-FRET effect. The systems will be based on three/four dyes connected with linkers cleavable to rele...

Organic chemistry

  • 2019 - 2021
    • •
  • 5 070 tis. Kč
    • •
  • 5 070 tis. Kč
    • •
  • GA ČR
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