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191 (0,076s) •

Project

The gene polymorphism of inflammatory cytokines as a risk factor of postoperative complications (NR9223)

polymorphism of chosen inflammatory mediators (TNF?, IL-1ß, IL-6, IL-8, IL-10, CRP...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2007 - 2009
    • •
  • 3 792 tis. Kč
    • •
  • 2 808 tis. Kč
    • •
  • MZ
Project

Nutritional modulation of adjuvant arthritis in rats interplay of leptin and ghrelin (GA305/06/0427)

) The temporal pattern of the expression and secretion of leptin and secretion of ghrelin, IL-1ß, IL-6, and other parameters of inflammation, as well as endocrine system-inflammatory cytokines (Interleukin-1, -6), ...

ED - Fyziologie

  • 2006 - 2008
    • •
  • 2 197 tis. Kč
    • •
  • 2 197 tis. Kč
    • •
  • GA ČR
Project

Gene screening of actinomycetes producing new substances with potential therapeutic applications to modulate immune mechanisms. (IAA600660607)

The project aims to acquire new secondary metabolites of the manumycin type from soil-isolated actinomycetes. These non-steroidal compounds show interesting immunomodulatory features (IL-1ß convertase inhibition) that could potentia...

EE - Mikrobiologie, virologie

  • 2006 - 2008
    • •
  • 4 337 tis. Kč
    • •
  • 4 337 tis. Kč
    • •
  • AV ČR
Project

Interleukin IL-6 in eye aqueous humor (IZ4096)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1997 - 1998
    • •
  • 528 tis. Kč
    • •
  • 528 tis. Kč
    • •
  • MZ
Project

Immunomodulatory ligands targeted to IL-23/Th17 pro-inflammatory axis as novel tools for development of topical drugs for treatment of psoriasis (NV16-27676A)

is regulated by secretion of interleukin-23 cytokine (IL-23) by activated dendritic cells, and mediated by the cognate IL-23 receptor (IL-23R), promoting intracellular signalization and secretion of IL-17...

FO - Dermatovenerologie

  • 2016 - 2019
    • •
  • 11 624 tis. Kč
    • •
  • 10 596 tis. Kč
    • •
  • MZ
Project

Quantification of intra-amniotic inflammation in late preterm prelabour rupture of membranes associated with the response of amniotic fluid proteome (NU21J-07-00058)

, the determination of interleukin-6 (IL-6) in amniotic fluid is frequently used to confirm or reject the presence of IAI in PPROM. However, the conclusive IL-6 cut-off value as a response to IAI may define the threshold ex...

Obstetrics and gynaecology

  • 2021 - 2024
    • •
  • 4 748 tis. Kč
    • •
  • 4 748 tis. Kč
    • •
  • MZ
Project

Interleukin-2 Activation of Autologous Peripheral blood stem cell. (IZ4253)

FD - Onkologie a hematologie

  • 1997 - 1998
    • •
  • 784 tis. Kč
    • •
  • 784 tis. Kč
    • •
  • MZ
Project

Immunomodulatory ligands suppressing function of human IL-23 (GAP303/10/1849)

Interleukin-23 (IL-23), a heterodimeric cytokine of covalently bound p19 to antibody-based drugs, we intend to engineer novel protein ligands suppressing IL-23 by a ribosome display will be used to generate high affinity bi...

FR - Farmakologie a lékárnická chemie

  • 2010 - 2013
    • •
  • 6 909 tis. Kč
    • •
  • 6 909 tis. Kč
    • •
  • GA ČR
Project

Comparison of expression of VEGF, TGF, IL6, IL10 and bounding proteins in oropharyngeal cancers and their metastasis with those in chronic tonsillitis (NC7487)

Quantification of expression of cytokines VEGF, TGF, HGF, IL-6 and IL-10 as a disease prognostic factor - graiding of oropharyngeal carcinoma. The prove of correlation between expression of VEGF, TGF, HGF, IL-6, IL...

FF - ORL, oftalmologie, stomatologie

  • 2003 - 2005
    • •
  • 2 784 tis. Kč
    • •
  • 2 771 tis. Kč
    • •
  • MZ
Project

Difficult to control asthma bronchiale The significance of some cytokines in its pathogenesis and the possibility of therapeutic intervention. (IZ1960)

FR - Farmakologie a lékárnická chemie

  • 1994 - 1996
    • •
  • 296 tis. Kč
    • •
  • 442 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 191