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417 (0,062s) •

Project

Study of antigens T and Tn and antibodies anti-T and anti-Tn in various neoplasias. (IZ1516)

9F - 9

  • 1993 - 1995
    • •
  • 300 tis. Kč
    • •
  • 600 tis. Kč
    • •
  • MZ
Project

Synthetic multiple antigenic glycopeptides (MAG) containing mucine antigenic determinants - potential diagnostics and cancer vaccines. (GA303/01/0690)

Cancer associated antigen of the mucin type play key-role in the tumour diagnostics. One of the most important glycoprotein structures of this type is MUC-1. This structure contains T, Tn and sialosyl-Tn tumour antigens...

EC - Imunologie

  • 2001 - 2003
    • •
  • 4 134 tis. Kč
    • •
  • 3 208 tis. Kč
    • •
  • GA ČR
Project

Solid phase synthesis of glycopeptide denrimers with T and TN antigenic structures and their biological activities (GA203/97/0176)

Tumour associated antigens of Tn and T type bound to branched oligolysine core (Multiple Antigenic Peptide, MAP) will be prepared by solid phase methodology. We intend andpearl cellulose. The structures of the type [Ac-(

CC - Organická chemie

  • 1997 - 1999
    • •
  • 3 418 tis. Kč
    • •
  • 2 524 tis. Kč
    • •
  • GA ČR
Project

Preparation and study of biologically active biopolymers and selected model-compounds (VS96140)

. Antigens of T, Tn and sTn will be synthesized on the polymeric resin. II. Study...

CC - Organická chemie

  • 1996 - 2000
    • •
  • 24 051 tis. Kč
    • •
  • 14 438 tis. Kč
    • •
  • MŠMT
Project

Molecular cytogenetic predictors of adjuvant therapy in patients with triple negative breast carcinoma (NS10286)

and C-MYC gene status in tumor cells of triple negative (TN) breast carcinoma gene as a predictor in TN breast cancer has not been published. HER1 in TN breast in TN breast cancer patients. 4.Proposed study would ...

FD - Onkologie a hematologie

  • 2009 - 2011
    • •
  • 3 593 tis. Kč
    • •
  • 3 562 tis. Kč
    • •
  • MZ
Project

Stereodirecting effects of deoxofluorination at C-3 and C-4 of 2-azido-2-deoxy-hexopyranosyl donors (GA17-18203S)

of regioselectively deoxofluorinated TN tumour-associated antigen....

CC - Organická chemie

  • 2017 - 2021
    • •
  • 5 324 tis. Kč
    • •
  • 4 664 tis. Kč
    • •
  • GA ČR
Project

Complex study of effects in low-dimensional quantum spin systems (8X17046)

- To investigate the characteristics of selected two-dimensional magnetically frustrated quantum system Cu(tn)Cl2 (tn=1,3 – diaminopropane = C3H10N2) from the first, to realize following particular goals: - To synthetize the single-...

BM - Fyzika pevných látek a magnetismus

  • 2017 - 2018
    • •
  • 180 tis. Kč
    • •
  • 180 tis. Kč
    • •
  • MŠMT
Project

Molecular biological basis of in vitro and in vivo interactions of stationary cultures of Salmonella spp. (GA524/98/1089)

will include the identification of Tn mutants and subsequently mutant genes (PCR inversion of Salmonella sp.; b) between Tn mutants and the parent strain S.typhimurium F98; c) between......

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 1998 - 2000
    • •
  • 2 788 tis. Kč
    • •
  • 2 696 tis. Kč
    • •
  • GA ČR
Project

Antidotes against HLA antigens and their importance for formation of chronical rejection. (ME 669)

We presuppose,that we will be able to prove asotiation between occurrence of antisubstance against HLA antigens of donor and chronical rejection of kidneys graft.......

FJ - Chirurgie včetně transplantologie

  • 2003 - 2004
    • •
  • 1 494 tis. Kč
    • •
  • 609 tis. Kč
    • •
  • MŠMT
Project

Recombinant antigens for diagnostic kits (OE85)

It is expected that bacterial expression and purification procedure will provide recombinant antigens of diagnostic importance in the standart and uniform qualities. The first commercially interesting antigens are: Glutathione s-tra...

FP - Ostatní lékařské obory

  • 2001 - 2003
    • •
  • 8 071 tis. Kč
    • •
  • 3 771 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 417