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Alternative splicing of SUCLG2 and mitochondrial complex II regulation in endocrine cancer (NW25-03-00282)
phenomenon that is relevant for endocrine tumours. We will study how the two variants regulate CII function and what impact this has on endocrine and other types of tumoursWe have recently described mutations in SUCLG2, a ...
Biochemistry and molecular biology
- 2025 - 2028 •
- 15 457 tis. Kč •
- 15 457 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2025 - 31. 12. 2028
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Endocrine regulation of circadian clock genes in relation to aging in an insect model (GAP502/10/1612)
Both circadian and endocrine mechanisms have been implicated in aging of model, Pyrrhocoris apterus, defined roles of endocrine tissues, neurosecretory cells of the brain), in the regulation of aging and showed that changes...
ED - Fyziologie
- 2010 - 2014 •
- 6 038 tis. Kč •
- 6 038 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2010 - 31. 12. 2014
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
The Role of SHBG in Endocrine Regulations and the Use of This Protein for Disclosure of Impairment of the Peripheral Sensitivity to Androgens (GA311/93/0985)
ED - Fyziologie
- 1993 - 1995 •
- 253 tis. Kč •
- 506 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 1993 - 1. 1. 1995
Uznané náklady
Podpora ze státního rozpočtu (200%)
Poskytovatel: Grantová agentura České republiky
Deciphering pancreas development and function at the single-cell level (GA25-15876S)
decisions, endocrine cell differentiation, and functional maturation of endocrine cells of Neurod1 altered the commitment of endocrine cell lineages and the differentiation of endocrine cells during pancreas devel...
Developmental biology
- 2025 - 2027 •
- 11 748 tis. Kč •
- 11 748 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2025 - 31. 12. 2027
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Endocrine control of life history "trade-offs" in males of insects with "non-functial" wing polymorphism (IAA6007301)
The aim of the project is to test the hypothesis that long- and short-winged males of Pyrrhocoris apterus differ in the pattern of endocrine regulation of life history strategies. The project is focused on determination of developme...
ED - Fyziologie
- 2003 - 2005 •
- 1 972 tis. Kč •
- 1 222 tis. Kč •
- AV ČR
Řešení projektu: 1. 1. 2003 - 1. 1. 2005
Uznané náklady
Podpora ze státního rozpočtu (62%)
Poskytovatel: Akademie věd České republiky
The role of less common androgen metabolites in endocrine regulations (NB5397)
The project deals with the role of 7- and 16-hydroxylated metabolites of DHEA/S in endocrine regilations as potential modulators of glucocorticoid effects, takink advantage of recently developed RIAs. Investigation of the levels of above men...
FB - Endokrinologie, diabetologie, metabolismus, výživa
- 1999 - 2001 •
- 3 521 tis. Kč •
- 2 835 tis. Kč •
- MZ
Řešení projektu: 1. 1. 1999 - 1. 1. 2001
Uznané náklady
Podpora ze státního rozpočtu (81%)
Poskytovatel: Ministerstvo zdravotnictví
Interactions of neuroendocrine and immune factors in male reproduction systeme. (NB5394)
This project will determine the factors involved in the endocrine-immune interactions in mucosal immune system of male reproductive tract and in the regulation of fertility.......
FB - Endokrinologie, diabetologie, metabolismus, výživa
- 1999 - 2002 •
- 4 547 tis. Kč •
- 3 850 tis. Kč •
- MZ
Řešení projektu: 1. 1. 1999 - 1. 1. 2002
Uznané náklady
Podpora ze státního rozpočtu (85%)
Poskytovatel: Ministerstvo zdravotnictví
Transcriptional and epigenetic control of pancreas development and function (GA22-11516S)
-secreting endocrine pancreatic ß cells. Developing treatments for pancreatic ß cell long mechanisms of functional changes in pancreatic endocrine development resulting from altered regulation of NEUROD1 transcriptional net...
Developmental biology
- 2022 - 2024 •
- 10 989 tis. Kč •
- 10 989 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2022 - 31. 12. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Interplay between ISLET1 and NEUROD1 in pancreatic development and disease (GA19-07378S)
abnormalities of the developing pancreatic endocrine tissue caused by the altered transcriptional regulation of NEUROD1 and ISLET1. We will also elucidate how mutations......
Physiology (including cytology)
- 2019 - 2022 •
- 9 516 tis. Kč •
- 9 516 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2019 - 30. 6. 2022
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Nutritional modulation of adjuvant arthritis in rats interplay of leptin and ghrelin (GA305/06/0427)
-directional immune-endocrine interactions. Leptin and ghrelin, both food intake-regulating-inflammatory cytokines (Interleukin-1, -6), which affect several endocrine axes-1ß, IL-6, and other parameters of inflammation, as ...
ED - Fyziologie
- 2006 - 2008 •
- 2 197 tis. Kč •
- 2 197 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2006 - 31. 12. 2008
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
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