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2 424 (0,106s) •

Project

Gene screening of actinomycetes producing new substances with potential therapeutic applications to modulate immune mechanisms. (IAA600660607)

of acquired compounds will be identified and their biological activity assayed, concentrating on the antiinflammatory and immunomodulatory features. from soil-isolated actinomycetes. These non-steroidal compounds ...

EE - Mikrobiologie, virologie

  • 2006 - 2008
    • •
  • 4 337 tis. Kč
    • •
  • 4 337 tis. Kč
    • •
  • AV ČR
Project

Compounds specifically affecting the biotransformation of arachidonic acid - perspective antiinflammatory and antiasthmatic drugs (GA203/97/0212)

The aim of this project is centered on the synthesis and biological testing of novel compounds, that antiinflammatory and/or antiasthmatic activitites are mediated through their influence on biological functions or biosynthesis of a...

CC - Organická chemie

  • 1997 - 1999
    • •
  • 1 281 tis. Kč
    • •
  • 1 177 tis. Kč
    • •
  • GA ČR
Project

Immunomodulatory properties of compounds isolated from Chinese medicinal herbs (ME10116)

The major aim of the project is the elucidation of molecular mechanisms underlying the therapeutic effectiveness of compounds isolated from five selected Chinese medicinal herbs with recorded anti-inflammatory and immunomodulatory e...

FR - Farmakologie a lékárnická chemie

  • 2010 - 2012
    • •
  • 2 145 tis. Kč
    • •
  • 2 145 tis. Kč
    • •
  • MŠMT
Project

Immunomodulatory potencies of toxic cyanobacteria (GP13-27695P)

metabolites including several inflammatory and immunomodulatory agents, but only fewof. The overall objective is to bring missing information on cyanobacterial immunomodulatory compounds in cyanobacteria.......

DJ - Znečištění a kontrola vody

  • 2013 - 2015
    • •
  • 2 021 tis. Kč
    • •
  • 2 021 tis. Kč
    • •
  • GA ČR
Project

Screening of antibacterial and anti-inflammatory activity of selected species of genus Nigella L. (GA525/02/0257)

Project deals with determination of antibacterial, anti-inflammatory and immunomodulatory activities of selected species of the genus Nigella L. (mainly of species N for antibacterial (dilution, diffusion and bioautographic methods), imm...

GM - Potravinářství

  • 2002 - 2004
    • •
  • 2 044 tis. Kč
    • •
  • 1 684 tis. Kč
    • •
  • GA ČR
Project

The development of VUFB-19 363, the original antiastmatic with multiple mechanism of action. (FB-C3/09)

. The research of antiinflammatory compounds will be continued during the mentioned period....

CC - Organická chemie

  • 2000 - 2001
    • •
  • 9 637 tis. Kč
    • •
  • 4 664 tis. Kč
    • •
  • MPO
Project

Metal-based compounds for enhanced cancer immunotherapy (GA21-27514S)

The metal-based compounds or their combinations with non-metal-based compounds capable of immunomodulatory activity will be introduced. The results will support the utility of the concept of new anticancer “multi-action” ag...

Pharmacology and pharmacy

  • 2021 - 2023
    • •
  • 7 352 tis. Kč
    • •
  • 7 112 tis. Kč
    • •
  • GA ČR
Project

Analysis of antiinflammatory properties of selected substances of bacterial and plant origin in experimental colitis therapy and prevention (KJB500200904)

The aim of our project is to use substances of bacterial and plant origin, which have been shown to have antiinflammatory properties, in mouse models of intestinal inflammation and to study the nature of this effect. We will also study if th...

EC - Imunologie

  • 2009 - 2011
    • •
  • 2 292 tis. Kč
    • •
  • 2 292 tis. Kč
    • •
  • AV ČR
Project

The evaluation of the possible effect of nonsteroidal antiinflammatory agent (ibuprofen) combined with antibiotics on the development of postpyelonephritic renal scarring in children (NK6526)

To define the incidence and persistence of renal postpyelonephritic scars in children based on age, clinical status, inflammatory markers, acute urinary concentrations of proinflammatory cytokines, interleukin-6 (IL-6). To evaluate the hypothesis of ...

FP - Ostatní lékařské obory

  • 2001 - 2003
    • •
  • 852 tis. Kč
    • •
  • 852 tis. Kč
    • •
  • MZ
Project

Natural bioactive compounds encapsulated in glucan microparticles as biomaterials suitable in the treatment of inflammatory bowel diseases (NV16-27522A)

of active natural compounds with positive effect in therapy of IBD is intensively-documented immunomodulatory effect - was not tested so far. Glucan microparticles can serve as carriers for biologically active compounds to...

FR - Farmakologie a lékárnická chemie

  • 2016 - 2019
    • •
  • 10 350 tis. Kč
    • •
  • 10 350 tis. Kč
    • •
  • MZ
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