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70 (0,127s) •

Project

Design and characterization of new photosensitizers and investigation of their interaction with target biological molecules (GA203/04/0426)

of more efficient drugs (photosensitizers). The research will quantitatively characterize molecular interactions between photosensitizer in the ground and excited systems. Specific objectives are: (1) To design the structure of the...

CA - Anorganická chemie

  • 2004 - 2006
    • •
  • 2 526 tis. Kč
    • •
  • 2 526 tis. Kč
    • •
  • GA ČR
Project

Self-assembling photosensitive materials with multiple functionality (GA16-12150S)

The project is focused on the study of photosensitive materials with self-assembling abilities on meso-and nano-scopic length scale an with a possibility derivatives, materials containing photosensitive spiropyran/spirooxazine moiet...

JJ - Ostatní materiály

  • 2016 - 2018
    • •
  • 7 732 tis. Kč
    • •
  • 6 973 tis. Kč
    • •
  • GA ČR
Project

Excitation of photosensitizer (GA203/98/P257)

Photodynamic therapy generally requires a photosensitizer accumulated in tumors and local excitation by visible light usually delivered from lasers and delivered these cells involves the formation of the triplet excited state of the phot...

CF - Fyzikální chemie a teoretická chemie

  • 1998 - 2000
    • •
  • 506 tis. Kč
    • •
  • 491 tis. Kč
    • •
  • GA ČR
Project

Photodynamic therapy of tumors (GA312/96/0518)

activation of photosensitizer selectively accumulated in the tumour tissue. Activation of clinical testing for intravenous application of own synthesised photosensitizer meso photosensitizers with higher effciency, yet unu...

BO - Biofyzika

  • 1996 - 1998
    • •
  • 4 355 tis. Kč
    • •
  • 4 247 tis. Kč
    • •
  • GA ČR
Project

Analysis of novel generation of photosensitizers mechanism of action and potential use for photodynamic therapy (GA301/01/0976)

The aim of this project is to study mechanism of action of a new generation of photosensitizers (PS) prepared on the basis of oligopyrrolic macrocycles, namely porphyrins and expanded porphyrins, and optimizing conditions for their applicati...

EB - Genetika a molekulární biologie

  • 2001 - 2003
    • •
  • 2 900 tis. Kč
    • •
  • 1 700 tis. Kč
    • •
  • GA ČR
Project

Photosensitizers based on aluminium phtalocyanine suitable for photodynamic therapy of cancer. (FD-K3/064)

The continuance of development of photosensitizers, pure disulfonated hydroxyaluminium phthalocyanine and subsequent finishing of it into a drug form. All the pre-clinical tests necessary for SÚKL approval and working out......

FD - Onkologie a hematologie

  • 2003 - 2005
    • •
  • 29 232 tis. Kč
    • •
  • 9 000 tis. Kč
    • •
  • MPO
Project

Nanofabrics as a photosensitizer carrier for aseptic leg ulcer dressing improve the life quality in patients with chronic wound (NS10093)

Leg ulcer represents very often therapeutically difficult situation. In the present proposal we will investigate an effect of autodisinfecting properties of polymerized nanofabrics colonized by molecules of nonpolar porphyrin photosensitizer...

FO - Dermatovenerologie

  • 2008 - 2011
    • •
  • 1 986 tis. Kč
    • •
  • 1 986 tis. Kč
    • •
  • MZ
Project

Azaphthalocyanines-a new group of photosensitizers for PDT (GP203/07/P445)

of a photosensitizer, light of proper wavelength and oxygen (effective response is given and more active photosensitizers. This project wants to contribute in a field azaphthalocyanine photosensitizer and the best suited s...

CC - Organická chemie

  • 2007 - 2009
    • •
  • 815 tis. Kč
    • •
  • 815 tis. Kč
    • •
  • GA ČR
Project

Synthesis, phase behaviour and photooptical properties of new challenging liquid crystalline polymers (LH15305)

Russian (RUS) and Czech (CZE) teams is to develop unique photosensitive chiral low photosensitive chiral liquid crystalline monomers with different structure of the molecular-optical and structural properties (CZE team). To design ...

BM - Fyzika pevných látek a magnetismus

  • 2015 - 2017
    • •
  • 1 735 tis. Kč
    • •
  • 1 735 tis. Kč
    • •
  • MŠMT
Project

The Utilization of Hypericin (Natural Product Derived from Plant Hypericum Perforatum) in Photodynamic Therapy and Diagnosis in Dermatology (NR7901)

The purpose of this study is a verification of the possibility of medical and more economic utilization of a new photosensitizer for photodynamic therapy and diagnosis.......

FO - Dermatovenerologie

  • 2004 - 2006
    • •
  • 1 123 tis. Kč
    • •
  • 1 020 tis. Kč
    • •
  • MZ
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