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1 146 (0,11s)

Project

The study of the relation between Epstein-Barr virus infection and development of IgA nephropathy (NV15-33686A)

that Epstein-Barr virus infection could be involved in initiation of IgAN - EBV-infected B infection with markers of clinical activity of IgAN. Second we propose to prove the possibility that EBV infe...

EC - Imunologie

  • 2015 - 2018
  • 6 427 tis. Kč
  • 6 427 tis. Kč
  • MZ
Project

Preparation and diagnostic use of recombinant proteins derived from early antigen (EA) of Epstein-Barr virus (EBV). (FB-C3/17)

The project is aimed at production and use of recombinant proteins derived from proteins of the early antigen complex (EA) of Epstein-Barr virus (EBV). Proteins of EA complex are of great importance to differential diagnostics of di...

EI - Biotechnologie a bionika

  • 2000 - 2002
  • 6 297 tis. Kč
  • 2 999 tis. Kč
  • MPO
Project

Transcriptional regulation of EpsteinBarr oncovirus – biophysical implications for Rta-targeted therapy (GA23-05241S)

Epstein-Barr virus (EBV) causes more than 138 000 deaths worldwide annually through associated cancers. EBV is also closely associated with mononucleosis infection, we will investigate the possibility of specific inhibition...

Biophysics

  • 2023 - 2025
  • 12 612 tis. Kč
  • 12 612 tis. Kč
  • GA ČR
Project

Diagnostic Imortance of IgE and Low-Avidity IgG against Epstein-Barr Virus Capsid Antigen in Children. (IZ3010)

9F - 9

  • 1995 - 1995
  • 0 tis. Kč
  • 0 tis. Kč
  • MZ
Project

Plasma EBV-DNA as a biomarker of treatment for EBV-positive Hodgkin's lymphoma and its predictive value for outcome (NR9166)

By means of new biological predictive marker individualize therapy of Hodgkin's lymphoma aiming at reduction of treatment toxicity without jeopardizing the effectiveness. Plasma EBV-DNA as a non-invasive biomarker in EBV-positive Hodgkin's lymphoma. ...

FD - Onkologie a hematologie

  • 2007 - 2009
  • 3 470 tis. Kč
  • 3 449 tis. Kč
  • MZ
Project

Study of interactions of biological macromolecules and nanolayers with a view to research of polymer microfluidic biosensors and therapeutic nanoparticles (KAN208240651)

Aim of the proposed project is a research of highly integrated microfluidic equipment (biosensors) based on the detection of biologically specific components from the sample using immobilized protein nanolayers and a research of organization of macro...

CI - Průmyslová chemie a chemické inženýrství

  • 2006 - 2010
  • 19 997 tis. Kč
  • 17 458 tis. Kč
  • AV ČR
Project

Inherited thrombocytopenias caused by mutations in the gene (MYH9) encoding nonmuscle myosin (NR8762)

In our study we will focus on DNA and protein analysis and correlation between mutations and clinical manifestations in patients with MYH9-related disorders.......

EB - Genetika a molekulární biologie

  • 2006 - 2008
  • 6 581 tis. Kč
  • 6 012 tis. Kč
  • MZ
Project

Deciphering the pathogenesis of pediatric post-transplant lymphoproliferative disorders (NW25J-03-00076)

. While Epstein-Barr virus (EBV) has been recognized to play a central role...

Hematology

  • 2025 - 2028
  • 6 993 tis. Kč
  • 6 993 tis. Kč
  • MZ
Project

Construction and large-scale production of recombinant proteins, derived from Epstaein-Barr virus nuclear antigen 1 (EBNA 1), and their application to the diagnostics of infectious diseasea. (FT-TA2/015)

The aim of this project is to construct recombinant proteins, which contain only virus-specific antigenic determinants of EBNA 1, to verify their suitability for diagnostic purpose, and to use them for an arrangement of ELISA-based diagnostic kit for...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2005 - 2007
  • 4 344 tis. Kč
  • 1 616 tis. Kč
  • MPO
Project

Clinical and Epidemiological Characteristics of Rotaviral and Astroviral Infections (NI6036)

During the research, 1200 children, as a minimum sample, up to 4 years of age who will be hospitalized in Infection Clinic in Pilsen will be examined and the incidence of rotaviruses and astroviruses will be checked. On the basis of rotaviru...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2000 - 2002
  • 1 678 tis. Kč
  • 1 648 tis. Kč
  • MZ
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