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17 (0,107s) •

Project

Hybrid magnetic "stealth" nano-structures for the targeted and controlled release of doxorubicin (7AMB12GR026)

The present research proposal aims to advance a step further the design and performance of physically targeted drug nanocarriers for cationic drugs such as doxorubicin - a potent drug but with serious side effects. Therefore, new multifuncti...

CA - Anorganická chemie

  • 2012 - 2013
    • •
  • 114 tis. Kč
    • •
  • 114 tis. Kč
    • •
  • MŠMT
Project

In-silico Workflow for Lipid-Mediated Active Pharmaceutical Ingredients Delivery Systems (GA25-18467S)

Lipid-mediated active pharmaceutical ingredients (APIs) delivery systems have enormous potential for the treatment of cancer or rare diseases. Lipid nanocarriers (LNCs) offer a versatile platform capable of delivering APIs, from small drugs ...

Physical chemistry

  • 2025 - 2027
    • •
  • 5 109 tis. Kč
    • •
  • 5 109 tis. Kč
    • •
  • GA ČR
Project

A robust reactive-oxygen-species scavenging nanomedicine for antioxidant therapy (GA25-15996S)

-responsive nanocarrier to deliver the antioxidant nanozymes at targeted sites to regulate nanocarriers in vitro regarding their cytotoxicity, cellular uptake, stimuli-responsive......

Health-related biotechnology

  • 2025 - 2027
    • •
  • 12 933 tis. Kč
    • •
  • 12 864 tis. Kč
    • •
  • GA ČR
Project

Nanopesticides in the environment – understanding their fate, bioavailability, effects and risks in soil and water (GA18-19324S)

particle chemistry, bound vs free pesticides, and loaded vs free nanocarriers...

Environmental sciences (social aspects to be 5.7)

  • 2018 - 2022
    • •
  • 6 338 tis. Kč
    • •
  • 5 992 tis. Kč
    • •
  • GA ČR
Project

Cluster-based nanoparticles for theranostics (8J20FR008)

into nanocarriers (PLGA). This includes the deliberate functionalization of the Mo6 complexes and the nanocarrier surfaces. 2. Photophysical and photochemical functionality. Time-resolved......

Inorganic and nuclear chemistry

  • 2020 - 2022
    • •
  • 146 tis. Kč
    • •
  • 146 tis. Kč
    • •
  • MŠMT
Project

Multidisciplinary research to increase application potential of nanomaterials in agricultural practice (EF16_025/0007314)

"• RI I - Advanced nanomaterials and use of protein cages for their targeted transport • RI II - Use of advanced nanomaterials for treating mastitis of farm animals • RI III - Use of advanced nanomaterials for ensuring sterility and antimicrobiality ...

Veterinary science

  • 2018 - 2022
    • •
  • 79 947 tis. Kč
    • •
  • 79 947 tis. Kč
    • •
  • MŠMT
Project

STIMULI RESPONSIVE NANOCARRIERS FOR HIGHLY EFFICIENT POLYMER THERAPEUTICS (GCP207/12/J030)

The project focuses on design, synthesis and study of physicochemical and biological properties of the highly sophisticated star and micellar high-molecular-weight polymer-based anti-cancer nanomedicines intended for efficient site-specific therapy o...

CD - Makromolekulární chemie

  • 2012 - 2015
    • •
  • 6 608 tis. Kč
    • •
  • 6 608 tis. Kč
    • •
  • GA ČR
Project

Construction of modified apoferritin nanocarriers bearing anticancer drugs and study of mechanisms enhancing their efficiency in anticancer therapy (GA17-12816S)

The project aims on a study of development of the surface and structural modifications of the protein nanotransporter apoferritin for targeted delivery of anticancer drugs. We focus on a design and testing of modifications, which will be suitable for...

CE - Biochemie

  • 2017 - 2019
    • •
  • 9 070 tis. Kč
    • •
  • 8 725 tis. Kč
    • •
  • GA ČR
Project

Lipid membrane models – a new tool for studying pathophysiology of skin diseases at a molecular level (GA13-23891S)

delivered (pseudo)ceramides using lipid nanocarriers. This project will be the first...

FR - Farmakologie a lékárnická chemie

  • 2013 - 2017
    • •
  • 9 734 tis. Kč
    • •
  • 9 734 tis. Kč
    • •
  • GA ČR
Project

Targeting resistance to chemotherapy of tumor cells to reinstate their susceptibility to novel, existing and unsuccessful anticancer metallodrugs (GA18-09502S)

With the intention to better understand the effects, which may play an important role in the biological (pharmacological) action of new combinations of anticancer metallodrugs and agents capable of targeting mechanisms connected with resistance of tu...

Medicinal chemistry

  • 2018 - 2020
    • •
  • 6 180 tis. Kč
    • •
  • 5 568 tis. Kč
    • •
  • GA ČR
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