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4 505 (0,152s) •

Project

Targeted polymer therapeutics for advanced treatment of site-specific rheumatic musculoskeletal diseases (NU20-08-00255)

The project is predominantly focused on applied research of therapeutic polymer nanomedicines for targeted therapy of rheumatic musculoskeletal diseases, especially. The main aim of the project is preclinical evaluation of thera...

Rheumatology

  • 2020 - 2023
    • •
  • 15 142 tis. Kč
    • •
  • 15 142 tis. Kč
    • •
  • MZ
Project

Optimazation of therapeutic inhaled aerosols targeted delivery (ME09030)

Optimization of aerosol characteristics from the point of their size, mass and shape (namely large porous particles and fiber particles)with the goal to ensure their targeted delivery into lung periphery for the treatment of some diseases......

BK - Mechanika tekutin

  • 2009 - 2012
    • •
  • 3 295 tis. Kč
    • •
  • 2 095 tis. Kč
    • •
  • MŠMT
Project

Targeted taxane derivatives as potential therapeutic possibility in the treatment of resistant and highly aggresive forms of tumors (LUAUS23164)

The main goal of the proposed project is to delineate mechanisms of action of the novel targeted taxane derivatives, e.g. derivatives conjugated with biotin and folate, on cancer cells in order to find new and effective therapeutic ...

Pharmacology and pharmacy

  • 2023 - 2027
    • •
  • 9 680 tis. Kč
    • •
  • 9 680 tis. Kč
    • •
  • MŠMT
Project

*Therapeutic laser (FR-TI3/368)

*The target of the project is to design high power laser for treating diseases of muscle skeletal system.Developed device will use modern diode laser source and main aim of the device is to offer better therapeutically result in com...

FS - Lékařská zařízení, přístroje a vybavení

  • 2011 - 2013
    • •
  • 22 756 tis. Kč
    • •
  • 11 311 tis. Kč
    • •
  • MPO
Project

Strategies for specific targeting of brain metastasis microenvironment for diagnostic and therapy (NU22-03-00318)

a promising diagnostic and therapeutic target. Fibroblast activation protein (FAP the hypothesis that FAP is a potential diagnostic and therapeutic target in brain metastases in adults. The median survival is less...

Radiology, nuclear medicine and medical imaging

  • 2022 - 2025
    • •
  • 12 326 tis. Kč
    • •
  • 12 326 tis. Kč
    • •
  • MZ
Project

Identification of new prognostic markers and therapeutic target molecules in soft tissue sarcoma (GA17-17636S)

markers and/or therapeutic targets for soft tissue sarcomas. We will start clinical history. If new therapeutic targets will be revealed, we will start......

FD - Onkologie a hematologie

  • 2017 - 2021
    • •
  • 8 858 tis. Kč
    • •
  • 8 858 tis. Kč
    • •
  • GA ČR
Project

Targeted experimental therapy of leukemia by the specific action of antireceptor monoclonal antibodies (NR8233)

Selection and development of new therapeutically useful antibodies for targeted therapy of acute and chronic myeloid leukemia....

FD - Onkologie a hematologie

  • 2004 - 2006
    • •
  • 6 514 tis. Kč
    • •
  • 5 948 tis. Kč
    • •
  • MZ
Project

T-MAPs High content mapping of surface molecules in normal and disturbed development T lymphocytes, a search for diagnostic and therapeutic targets (NU20-05-00282)

interaction and thus are important targets of therapeutic interventions. At the same time their utility as therapy targets, diagnostic targets and immunopathology biomarkers syndrome; c) chronic inflammation in cy...

Immunology

  • 2020 - 2023
    • •
  • 9 118 tis. Kč
    • •
  • 9 118 tis. Kč
    • •
  • MZ
Project

Novel concepts for the therapeutic targeting of tumor microenvironment in human glioblastomas (NV15-31379A)

expression in healthy tissues, the protease is a proposed therapeutic target and FAP+ mesenchymal cells as potential therapeutic targets in HGG. In parallel, novel proprietary compounds utilizing FAP inhibitors as...

FD - Onkologie a hematologie

  • 2015 - 2019
    • •
  • 15 595 tis. Kč
    • •
  • 15 595 tis. Kč
    • •
  • MZ
Project

Polymer conjugates of drugs targeted with specific oligopeptides (GA204/05/2255)

systémrepresents a unique system enabling duál drug targeting and dual therapeutic activity of the polymer drug. Dual targeting will be achieved by combination of an active targeting and biological properties of a...

CD - Makromolekulární chemie

  • 2005 - 2007
    • •
  • 5 421 tis. Kč
    • •
  • 5 421 tis. Kč
    • •
  • GA ČR
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