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Tissue and soluble endoglin and their importance in endothelial dysfunction and atherogenesis in vivo and in vitro (GA15-24015S)
Endoglin is a TGF-β receptor III, which is important for the function of endothelium, and its tissue and soluble form was detected in atherosclerosis. Endoglin process. Moreover, we would like to study the role of tissu...
FA - Kardiovaskulární nemoci včetně kardiochirurgie
- 2015 - 2017 •
- 5 760 tis. Kč •
- 5 760 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2015 - 31. 12. 2017
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
The relationship of soluble endoglin and hypercholesterolemia in patients with type 2 diabetes mellitus and the impact of therapeutical intervention. (NV17-31754A)
Soluble endoglin (Sol-Eng) levels are increased in blood during serious pathological conditions related to hypercholesterolemia, diabetes mellitus (DM), and inflammation. This grant project brings a prospective randomized study with 104 pati...
FB - Endokrinologie, diabetologie, metabolismus, výživa
- 2017 - 2020 •
- 8 915 tis. Kč •
- 8 915 tis. Kč •
- MZ
Řešení projektu: 1. 4. 2017 - 31. 12. 2020
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Impact of direct endoglin modulation on the development of major complications of metabolic syndrome atherogenesis and non-alcoholic steatohepatitis (GA22-14961S)
Endoglin (Eng) plays a crucial role in the pathogenesis of endothelial dysfunction, atherogenesis, liver fibrosis, and non-alcoholic steatohepatitis (NASH). Carotuximab is a monoclonal antibody that directly affects the expression, and signa...
Pharmacology and pharmacy
- 2022 - 2024 •
- 8 954 tis. Kč •
- 8 954 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2022 - 31. 12. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Prediction of therapeutic response in ovarian cancer patients (NT14107)
effects). 2) Assay of polymorphisms of the Interleukin-8 gene, endoglin, FGF...
FK - Gynekologie a porodnictví
- 2013 - 2015 •
- 7 804 tis. Kč •
- 7 804 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2013 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
The clinical significance of angiogenic markers in patients with renal cell carcinoma (NR8914)
To verify the soluble and membrane associated angiogenic factors reflected the growth activity of renal cell carcinoma and set up there prognostic value. To pick out some parameters (VEGF, bFGF, TGF, CD105) to determine the risk of progression of RCC...
FN - Epidemiologie, infekční nemoci a klinická imunologie
- 2006 - 2009 •
- 3 619 tis. Kč •
- 3 616 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2006 - 31. 12. 2009
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Angiogenesis, plasma cell kinetics, parameters of microenvironments of bone marrow and bone metabolism in monoclonal gammopathy of undetermined significance and initial phases of multiple myeloma (NR9500)
Comparison of microvessel density and endothelial-cell proliferation inside bone marrow and serum levels of angiogenic cytokines (VEGF, HGF, bFGF, IL-17, endoglin, angiogenin and angiostatin) in MGUS, smoldering (SMM) and overt form of multi...
FD - Onkologie a hematologie
- 2007 - 2009 •
- 4 306 tis. Kč •
- 4 191 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2007 - 31. 12. 2009
Uznané náklady
Podpora ze státního rozpočtu (97%)
Poskytovatel: Ministerstvo zdravotnictví
Development of products obtained by processing human bone tissue for selected applications in tissue engineering and regenerative medicine (EG17_107/0012524)
The main focus of the project is the development of products obtained by processing human bone tissue for selected applications in tissue engineering and regenerative medicine. These products will serve as a bioactive ingredient for...
EI - Biotechnologie a bionika
- 2017 - 2021 •
- 13 204 tis. Kč •
- 0 tis. Kč •
- MPO
Řešení projektu: 30. 11. 2017 - 26. 10. 2021
Uznané náklady
Podpora ze státního rozpočtu (0%)
Poskytovatel: Ministerstvo průmyslu a obchodu
Direct effect of adipose tissue in atherosclerosis acceleration (NT14009)
A possible direct effect of adipose tissue to atherosclerotic changes in men will be analyzed using perivascular adipose tissue measurement in hearts explanted during heart transplantation. The size of perivascular adipose tissu...
FB - Endokrinologie, diabetologie, metabolismus, výživa
- 2013 - 2015 •
- 4 382 tis. Kč •
- 4 382 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2013 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Development of a unit for decellularization by supercritical CO₂, optimization of permeations and recipes for tissue decelularization and production of a bioactive scaffold equipped with mesenchymal (FW06010688)
on decellularized human tissue with subsequent mesenchymal stem cells. The basis will be the design of a decellularization unit for decellularization of tissues by supercritical CO₂, its implementation in the premises of the Nation...
Transplantation
- 2023 - 2027 •
- 29 191 tis. Kč •
- 20 186 tis. Kč •
- TA ČR
Řešení projektu: 1. 1. 2023 - 31. 12. 2027
Uznané náklady
Podpora ze státního rozpočtu (69%)
Poskytovatel: Technologická agentura ČR
Evolutionary conserved mechanisms underlying tissue-specific gene expression (ME 176)
Evolutionary conserved mechanisms of tissue specific gene expression: Project is aimed on the evolutionary conserved mechanisms of tissue specific gene expression of abundant and tissue specific genes in the labial gland. T...
EB - Genetika a molekulární biologie
- 1998 - 2000 •
- 1 770 tis. Kč •
- 570 tis. Kč •
- MŠMT
Řešení projektu: 1. 1. 1998 - 1. 1. 2000
Uznané náklady
Podpora ze státního rozpočtu (32%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
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