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Structural basis for transcription termination of nonpolyadenylated transcripts (IAA401630903)
RNA polymerases produce RNA transcripts by initiating and terminating transcription in response to specific sequence elements. Signals that terminate transcription reside either in the DNA template sequence or, alternativel...
CE - Biochemie
- 2009 - 2011 •
- 4 875 tis. Kč •
- 4 875 tis. Kč •
- AV ČR
Řešení projektu: 1. 1. 2009 - 31. 12. 2011
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Akademie věd České republiky
Structural characterisation of the interplay between transcription and DNA repair (GM21-10464M)
The interplay between DNA repair and transcription is a complex and poorly understood. On one hand, transcription is one of the mayor sources of DNA damage. On the other hand, under particular circumstances, cells use transcript...
Biochemistry and molecular biology
- 2021 - 2025 •
- 24 991 tis. Kč •
- 24 991 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2021 - 31. 12. 2025
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Crosstalk between transcription and translation (LL2008)
by ribosomes, thus coupling transcription to translation. Indeed, recent cryo-electron directly. This contrasts with eukaryotic transcription and translation which the possibility that viral transcription might be directly...
Genetics and heredity (medical genetics to be 3)
- 2020 - 2025 •
- 48 953 tis. Kč •
- 48 953 tis. Kč •
- MŠMT
Řešení projektu: 1. 7. 2020 - 30. 6. 2025
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
Study of molecular mechanisms involved in suppression of transcription-associated genomic instability (GA17-02080S)
DNA transcription can induce genomic instability by causing collapse by activated oncogenes in precancerous lesions. Transcription-associated genomic instability has been attributed to the formation of co-transcriptional RN...
EB - Genetika a molekulární biologie
- 2017 - 2019 •
- 9 174 tis. Kč •
- 7 836 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2017 - 31. 12. 2019
Uznané náklady
Podpora ze státního rozpočtu (85%)
Poskytovatel: Grantová agentura České republiky
Simultaneous gene transcription and translation (GJ20-16013Y)
directly coupling transcription to translation. This contrasts with eukaryotic transcription and translation which are physically separated by the nuclear envelope eukaryotic cells, raising the possibility that viral transcript...
Biochemical research methods
- 2020 - 2022 •
- 9 834 tis. Kč •
- 9 834 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2020 - 31. 12. 2022
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Transcription factor MITF in melanoma and transcription factor HASH1 in small cell lung carcinoma use in diagnosis and prognosis and their role in pathogenesis. (NR8026)
We propose to use multiple independent molecular approaches to elucidate the importance of the transcription factor MITF in the pathogenesis of human melanoma and the role of transcription factor HASH1 in small cell lung carcinoma. ...
FD - Onkologie a hematologie
- 2004 - 2006 •
- 4 747 tis. Kč •
- 4 661 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2004 - 1. 1. 2006
Uznané náklady
Podpora ze státního rozpočtu (98%)
Poskytovatel: Ministerstvo zdravotnictví
Yeast linear plasmids as a model for poxviral transcription (GA21-25504S)
-template sequences. The role of RNAPs, and the whole transcription apparatus in general transcription system based on unique transcription apparatus encoded by the linear plasmids length of promoters that can be recognized...
Microbiology
- 2021 - 2024 •
- 5 679 tis. Kč •
- 5 679 tis. Kč •
- GA ČR
Řešení projektu: 1. 4. 2021 - 31. 3. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Functional genomics of the nuclear hormone receptor transcription complex in human tumors (NC7554)
Functional genomics targeted on components of transcription complex of RNA Polymerase II order to improve diagnostics and therapy of tumors.......
FC - Pneumologie
- 2003 - 2005 •
- 4 353 tis. Kč •
- 4 325 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2003 - 1. 1. 2005
Uznané náklady
Podpora ze státního rozpočtu (99%)
Poskytovatel: Ministerstvo zdravotnictví
Mechanisms of transcriptional pulsing (GA16-12611S)
Live cell imaging revealed that high transcriptional activity often alternates with periods of prolonged transcriptional silence. This phenomenon, referred to as transcriptional pulsing, is currently attracting considerable...
EB - Genetika a molekulární biologie
- 2016 - 2017 •
- 3 289 tis. Kč •
- 3 289 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2016 - 31. 12. 2017
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
The study of the mechanism of suppression of transcription-born DNA damage by RECQL5β (GJ20-21581Y)
and endogenous factors. Only recently it has become apparent that transcription is a major mechanism by which RECQL5β inhibits RNAPII transcription. The combination of these two suppression of transcription-born genome ins...
Biochemistry and molecular biology
- 2020 - 2022 •
- 9 918 tis. Kč •
- 9 918 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2020 - 31. 12. 2022
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
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