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28 (0,061s) •

Project

Apoptotic changes in endometrial proliferation (NR9313)

Isufficient apoptosis is one of the causal factors of cancerogenesis and oncological treatment failure. Expression of apoptotic inhibitors has been proven in many human malignancies. The aim of this project is to detect the apoptotic changes...

FK - Gynekologie a porodnictví

  • 2007 - 2009
    • •
  • 2 627 tis. Kč
    • •
  • 2 584 tis. Kč
    • •
  • MZ
Project

Structure and function of interphase chromosomes (ME 565)

allow us to find out combinations of genes related to cancerogenesis. Changes differentiation and cancerogenesis.,...

BO - Biofyzika

  • 2002 - 2004
    • •
  • 2 544 tis. Kč
    • •
  • 1 201 tis. Kč
    • •
  • MŠMT
Project

Detection of preneoplastic changes and early bronchogenic carcinoma by autofluorescence bronchoscopy (NR7979)

cytology; studies on genetic basis of cancerogenesis....

FD - Onkologie a hematologie

  • 2004 - 2006
    • •
  • 2 711 tis. Kč
    • •
  • 2 580 tis. Kč
    • •
  • MZ
Project

Epigenetic control of gene expression in malignant diseases (NC6987)

to cancerogenesis. The structure of chromosomes will be inbestigated in interphase 3D-fixed and expression of genes during cancerogenesis. It may give us new and relatively cheap method......

EB - Genetika a molekulární biologie

  • 2002 - 2004
    • •
  • 7 130 tis. Kč
    • •
  • 3 885 tis. Kč
    • •
  • MZ
Project

The role of chronic inflammatory changes in pancreas in cancerogenesis (NR9295)

Tissue ischemia in chronic pancreatitis is one of the factors influencing oxidative stress; this stress is an important factor of changes leading towards carcinogenesis of the pancreas, in this case. The goal of this study is to predict changes that ...

FE - Ostatní obory vnitřního lékařství

  • 2007 - 2009
    • •
  • 5 129 tis. Kč
    • •
  • 5 129 tis. Kč
    • •
  • MZ
Project

Quantification of circulating tumor cells (CTC) in tumors of gastrointestinal tract (NT14439)

Molecular profiles of subpopulations of tumor cells, CTC (circulating tumor cells (CTC) are means of identifying individual changes in cancerogenesis and sensitivity to treatment (so-called "real time" tumor biopsy). The aim is to divide the...

FJ - Chirurgie včetně transplantologie

  • 2013 - 2015
    • •
  • 5 884 tis. Kč
    • •
  • 5 884 tis. Kč
    • •
  • MZ
Project

Circulating and disseminated tumor cells in diagnosis and treatment of advanced ovarian cancer. (NT14441)

of the individual differences in the cancerogenesis and cancer therapy process (so called “real...

FK - Gynekologie a porodnictví

  • 2013 - 2015
    • •
  • 4 589 tis. Kč
    • •
  • 4 589 tis. Kč
    • •
  • MZ
Project

Dynamics of oxidative stress during oncotherapy and prognosis of patients with head and neck carcinomas (NR9200)

According to our empirical experience and conclusions of other researchers, ability to cope with increased oxidative stress is strictly individual. Chemo- and radiosensitivity in patients with head and neck carcinomas are influenced by interindividua...

FF - ORL, oftalmologie, stomatologie

  • 2007 - 2009
    • •
  • 3 891 tis. Kč
    • •
  • 3 812 tis. Kč
    • •
  • MZ
Project

Molecular mechanisms of selected pathological processes in the cell (GD303/09/H048)

Project is focuse on revealing the molecular basis of pathological changes in animal cells and modulation of these processes through natural as well as synthetic substance effects. The main goal of this interdisciplinary and interregional project is ...

CE - Biochemie

  • 2009 - 2012
    • •
  • 8 688 tis. Kč
    • •
  • 8 688 tis. Kč
    • •
  • GA ČR
Project

Analysis of expression of STAT, JAK and SOCS in glial tumors of brain and in carcinomas of breast and prostate gland. Correlation with grading, expression of steroid receptors and expression of proteins regulating cell cycle and apoptosis. (1A8244)

Disruption of signaling of JAK/STAT/SOCS may be the cause of failure of immune surveillance and may participate in development and invasion of various tumors, including carcinomas of prostate gland, breast and glial tumors of brain. The aim is analys...

EB - Genetika a molekulární biologie

  • 2004 - 2006
    • •
  • 1 665 tis. Kč
    • •
  • 1 419 tis. Kč
    • •
  • MZ
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