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4 (0,061s)

Project

ROLE OF CYTOKINE PRIMING IN AZACITIDINE-MEDIATED LEUKEMIA STEM CELL DIFFERENTIATION IN THERAPY OF PROGRESSING MYELODYSPLASIA (GA18-01687S)

) Azacitidine (AZA) blocks progression to acute myeloid leukemia (AML) albeit all patients...

Oncology

  • 2018 - 2020
  • 10 226 tis. Kč
  • 10 082 tis. Kč
  • GA ČR
Project

Prediction of the response to demethylation treatment in patients with myelodysplastic syndromes using integrative genomics (NT14377)

plan to analyze CD34 + cells before and during treatment with azacitidine. We...

FD - Onkologie a hematologie

  • 2013 - 2015
  • 8 026 tis. Kč
  • 7 929 tis. Kč
  • MZ
Project

Role of transposable elements and PIWI-interacting RNAs in myelodysplastic syndrome and their potential clinical applications (NU20-03-00412)

of azacitidine treatment on TE and piRNA transcriptions will be addressed to prove...

Hematology

  • 2020 - 2024
  • 12 614 tis. Kč
  • 12 201 tis. Kč
  • MZ
Project

Clinically relevant substrates of proteasome degradation in MDS. (NU21-08-00312)

in clinical studies for MDS alongside the drug of choice in high risk MDS, Azacitidine...

Biochemistry and molecular biology

  • 2021 - 2024
  • 12 919 tis. Kč
  • 12 919 tis. Kč
  • MZ
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