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16 (0,068s) •

Project

Changes of number of stem tumor- cells in peripheral blood of patients with multiple myeloma in dependence on chemoterapy. (IZ2104)

FD - Onkologie a hematologie

  • 1994 - 1997
    • •
  • 520 tis. Kč
    • •
  • 665 tis. Kč
    • •
  • MZ
Project

Identification of new prognostic factors and markers of activity in multiple myeloma. Efficacy of new therapeutical approaches. (IZ3170)

FD - Onkologie a hematologie

  • 1995 - 1997
    • •
  • 886 tis. Kč
    • •
  • 848 tis. Kč
    • •
  • MZ
Project

Bone marrow microenvironment analysis in extramedullary relapse of multiple myeloma (NV17-29343A)

Extramedullary relapse (EM) of multiple myeloma is becoming another obstacle on the way towards improvement of quality of life of multiple myeloma (MM) patients. EM is characterized by aggressive disease course and shorter survival. EM is caused by t...

FD - Onkologie a hematologie

  • 2017 - 2021
    • •
  • 9 864 tis. Kč
    • •
  • 9 823 tis. Kč
    • •
  • MZ
Project

Multiparametric flow cytometry in study of malignant plasma cells pathophysiology (GP301/09/P457)

Immunophenotypisation of plasma cells using multiparametric flow cytometry brings enough data to define and distinguish heterogeneous population of neoplastic plasma cells from their normal equivalent. The aim of this project is to identify phenotypi...

FD - Onkologie a hematologie

  • 2009 - 2011
    • •
  • 1 200 tis. Kč
    • •
  • 1 200 tis. Kč
    • •
  • GA ČR
Project

University Research Centre - Czech Myeloma Group (LC06027)

This study is using the exceptional professional, personal, spatial and organizational conditions, including exceptional source of research material in the region, to create a center of European quality aimed at research of monoclonal gammopathies an...

FD - Onkologie a hematologie

  • 2006 - 2011
    • •
  • 59 965 tis. Kč
    • •
  • 59 587 tis. Kč
    • •
  • MŠMT
Project

In-depth genomic analysis of residual clone in multiple myeloma approach for individualized targeted therapy (NV17-30089A)

Mass of multiple myeloma aberrant cells represents at the time of diagnosis a mixture of multiple independent clones that vary in size with time. Population of aberrant cells of minimal residual disease (MRD) represents only a subset of clones from t...

FD - Onkologie a hematologie

  • 2017 - 2020
    • •
  • 12 922 tis. Kč
    • •
  • 12 922 tis. Kč
    • •
  • MZ
Project

Circulating nucleic acids as markers of multiple myeloma progression (NV15-29508A)

Multiple myeloma (MM) is the second most common hematooncological disease in the world characterized by multi-stage development. MM develops from monoclonal gammopathy of undetermined significance (MGUS) and may progress to aggressive form of MM - ex...

FD - Onkologie a hematologie

  • 2015 - 2018
    • •
  • 9 514 tis. Kč
    • •
  • 9 514 tis. Kč
    • •
  • MZ
Project

Using MALDI-TOF mass spectrometry for identification of molecular patterns in relapsed multiple myeloma patients (NU21-03-00076)

Multiple myeloma is the second most common hematological malignancy of the elderly. Median age at diagnosis is 65. Bone marrow transplants as well as new drugs (immunomodulatory drugs, proteasome inhibitors and monoclonal antibodies) significantly in...

Hematology

  • 2021 - 2024
    • •
  • 10 729 tis. Kč
    • •
  • 10 729 tis. Kč
    • •
  • MZ
Project

Aberrant plasma cells clonal diversification in immunoglobulin light chain amyloidosis (NV15-29667A)

Immunoglobulin light chain amyloidosis (ALA) is a haematological disorder and may coexist with other plasma cell (PC) dyscrasias. It has been reported that 10% of ALA patients may have multiple myeloma (MM) at the same time. Nevertheless, it is still...

FD - Onkologie a hematologie

  • 2015 - 2019
    • •
  • 8 743 tis. Kč
    • •
  • 8 623 tis. Kč
    • •
  • MZ
Project

A novel local therapy for myeloma bone disease (NU21-03-00032)

The outcome of patients with multyple myeloma (MM) has notably augmented as a consequence of new therapeutic approaches. Extend in life expectancy has increased the need for providing long-term supportive care and quality of life for these patients b...

Oncology

  • 2021 - 2024
    • •
  • 12 287 tis. Kč
    • •
  • 12 287 tis. Kč
    • •
  • MZ
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