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6 871 (0,107s)

Project

Study of the interaction between 14-3-3 protein and regulator of G protein signaling RGS3. (IAA501110801)

and regulators of G protein-effector interactions. RGS3 protein is one of the RGS proteins/RGS3 complex; (2) to study how 14-3-3 protein inhibits the interaction between RGS3 protein?dep...

BO - Biofyzika

  • 2008 - 2012
  • 5 095 tis. Kč
  • 5 095 tis. Kč
  • AV ČR
Project

Interaction proteins with surfaces. New biophysical methods for analysis of tumor supressos protein p53 (GP202/07/P497)

these methods for biophysical investigations of interactions of p53 proteins with DNA. Our preliminary results suggest that interaction of proteins with surfaces can yieldThe tumor suppressor protein play...

BO - Biofyzika

  • 2007 - 2009
  • 1 164 tis. Kč
  • 1 164 tis. Kč
  • GA ČR
Project

Structure-function relationships underlying protein-protein interactions (GAP305/10/2184)

understanding of protein-protein interactions. with computational chemists to unravel some fundamental principles underlying protein-protein interactions. In a case study building on several avai...

EB - Genetika a molekulární biologie

  • 2010 - 2014
  • 8 276 tis. Kč
  • 8 276 tis. Kč
  • GA ČR
Project

New tools of label-free electrochemical analysis of protein interactions with nucleic acids and proteins (GA18-18154S)

to better understanding of dynamics of DNA-protein and protein-protein interactions that can contribute by new insights about complex protein systems. We wish to take advantage of electrochemical approach...

Biophysics

  • 2018 - 2021
  • 3 613 tis. Kč
  • 3 433 tis. Kč
  • GA ČR
Project

Monitoring protein-protein interactions in vivo (IAA500960802)

Nearly all biochemical, physiological and regulatory processes depend on protein-protein interactions. Their dynamics and strength is crucial and even subtle affect interactions in question. One of the challenges i...

EB - Genetika a molekulární biologie

  • 2008 - 2012
  • 4 084 tis. Kč
  • 4 084 tis. Kč
  • AV ČR
Project

Effect of protein hydration shell on the stability of protein complexes. (GPP205/12/P729)

Protein-protein interactions are at the basis of almost all cellular processes between surface properties of both protein monomers taking part in the interaction, but plays an active part in determining th...

CF - Fyzikální chemie a teoretická chemie

  • 2012 - 2017
  • 2 037 tis. Kč
  • 2 037 tis. Kč
  • GA ČR
Project

Study of WD-protein function in actinomycetes (IAA5020207)

and transport. The function of WD40 repeats themselves in particular proteins, insofar as their function is known, consists in protein-protein interaction and in building up functional protein complexes. ...

EB - Genetika a molekulární biologie

  • 2002 - 2005
  • 3 839 tis. Kč
  • 3 186 tis. Kč
  • AV ČR
Project

Application of combinatorial libraries of affinity carriers for the identificatio of new interactions of the protein-ligand type (IAB4055003)

is needed for the identification of the protein-ligand interaction. This procedureWe propose a new method for the idetification of unknown interactions between a variety of proteins and ligands. The principe of th...

CE - Biochemie

  • 2000 - 2002
  • 2 242 tis. Kč
  • 1 384 tis. Kč
  • AV ČR
Project

Investigation of molecular architecture and molecular interactions of biologically important proteins and their protein domains (VS96141)

of the current project is the preparation of key protein components from selected biological, and interactions with specific ligands. In collaboration with other laboratories home, molecular genetics, recombinant expression of ...

EA - Morfologické obory a cytologie

  • 1996 - 2000
  • 36 562 tis. Kč
  • 30 374 tis. Kč
  • MŠMT
Project

Molecular studies on the structure of the heteromeric GABA-B receptors (NF6704)

The aim of our studies is to map portions of the BR1 and BR2 proteins that are in close proximity and contribute to the protein-protein interactions that are involvolved in the structural formation of the functiona...

FE - Ostatní obory vnitřního lékařství

  • 2001 - 2003
  • 1 849 tis. Kč
  • 1 723 tis. Kč
  • MZ
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